Effect of gamma rays on the bone repair process in rats with estrogen deficiency
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Oral Research |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242007000100013 |
Resumo: | This study aimed at evaluating the bone repair process in ovariectomized rats submitted to an irradiation procedure. For this purpose, one hundred rats were randomly divided in four experimental groups: control, ovariectomized, irradiated and irradiated/ovariectomized. A bone defect was made on all animals' tibias. Three days after surgery, only irradiated and irradiated/ovariectomized rats received 8 Gy of gamma rays on the lower limbs region. The animals were sacrificed 7, 14, 21 and 28 days after surgery in order to assess the repair process. It was possible to observe a delay in the bone repair process in the irradiated/ovariectomized group, in which there was a remarkable association between estrogen deficiency and ionizing radiation resulting in the reduction of newly formed bone production, thus accelerating the resorption process. |
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Effect of gamma rays on the bone repair process in rats with estrogen deficiencyEstrogensOsteoporosisOvariectomyBone and bonesFracture healingThis study aimed at evaluating the bone repair process in ovariectomized rats submitted to an irradiation procedure. For this purpose, one hundred rats were randomly divided in four experimental groups: control, ovariectomized, irradiated and irradiated/ovariectomized. A bone defect was made on all animals' tibias. Three days after surgery, only irradiated and irradiated/ovariectomized rats received 8 Gy of gamma rays on the lower limbs region. The animals were sacrificed 7, 14, 21 and 28 days after surgery in order to assess the repair process. It was possible to observe a delay in the bone repair process in the irradiated/ovariectomized group, in which there was a remarkable association between estrogen deficiency and ionizing radiation resulting in the reduction of newly formed bone production, thus accelerating the resorption process.Sociedade Brasileira de Pesquisa Odontológica - SBPqO2007-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242007000100013Brazilian Oral Research v.21 n.1 2007reponame:Brazilian Oral Researchinstname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)instacron:SBPQO10.1590/S1806-83242007000100013info:eu-repo/semantics/openAccessChicarelli,MarilianiRamos,Flávia Maria de MoraesManzi,Flávio RicardoNovaes,Pedro DuarteBóscolo,Frab NorbertoAlmeida,Solange Maria deeng2007-03-23T00:00:00Zoai:scielo:S1806-83242007000100013Revistahttps://www.scielo.br/j/bor/https://old.scielo.br/oai/scielo-oai.phppob@edu.usp.br||bor@sbpqo.org.br1807-31071806-8324opendoar:2007-03-23T00:00Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)false |
dc.title.none.fl_str_mv |
Effect of gamma rays on the bone repair process in rats with estrogen deficiency |
title |
Effect of gamma rays on the bone repair process in rats with estrogen deficiency |
spellingShingle |
Effect of gamma rays on the bone repair process in rats with estrogen deficiency Chicarelli,Mariliani Estrogens Osteoporosis Ovariectomy Bone and bones Fracture healing |
title_short |
Effect of gamma rays on the bone repair process in rats with estrogen deficiency |
title_full |
Effect of gamma rays on the bone repair process in rats with estrogen deficiency |
title_fullStr |
Effect of gamma rays on the bone repair process in rats with estrogen deficiency |
title_full_unstemmed |
Effect of gamma rays on the bone repair process in rats with estrogen deficiency |
title_sort |
Effect of gamma rays on the bone repair process in rats with estrogen deficiency |
author |
Chicarelli,Mariliani |
author_facet |
Chicarelli,Mariliani Ramos,Flávia Maria de Moraes Manzi,Flávio Ricardo Novaes,Pedro Duarte Bóscolo,Frab Norberto Almeida,Solange Maria de |
author_role |
author |
author2 |
Ramos,Flávia Maria de Moraes Manzi,Flávio Ricardo Novaes,Pedro Duarte Bóscolo,Frab Norberto Almeida,Solange Maria de |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Chicarelli,Mariliani Ramos,Flávia Maria de Moraes Manzi,Flávio Ricardo Novaes,Pedro Duarte Bóscolo,Frab Norberto Almeida,Solange Maria de |
dc.subject.por.fl_str_mv |
Estrogens Osteoporosis Ovariectomy Bone and bones Fracture healing |
topic |
Estrogens Osteoporosis Ovariectomy Bone and bones Fracture healing |
description |
This study aimed at evaluating the bone repair process in ovariectomized rats submitted to an irradiation procedure. For this purpose, one hundred rats were randomly divided in four experimental groups: control, ovariectomized, irradiated and irradiated/ovariectomized. A bone defect was made on all animals' tibias. Three days after surgery, only irradiated and irradiated/ovariectomized rats received 8 Gy of gamma rays on the lower limbs region. The animals were sacrificed 7, 14, 21 and 28 days after surgery in order to assess the repair process. It was possible to observe a delay in the bone repair process in the irradiated/ovariectomized group, in which there was a remarkable association between estrogen deficiency and ionizing radiation resulting in the reduction of newly formed bone production, thus accelerating the resorption process. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242007000100013 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242007000100013 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1806-83242007000100013 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Pesquisa Odontológica - SBPqO |
publisher.none.fl_str_mv |
Sociedade Brasileira de Pesquisa Odontológica - SBPqO |
dc.source.none.fl_str_mv |
Brazilian Oral Research v.21 n.1 2007 reponame:Brazilian Oral Research instname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO) instacron:SBPQO |
instname_str |
Sociedade Brasileira de Pesquisa Odontológica (SBPqO) |
instacron_str |
SBPQO |
institution |
SBPQO |
reponame_str |
Brazilian Oral Research |
collection |
Brazilian Oral Research |
repository.name.fl_str_mv |
Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO) |
repository.mail.fl_str_mv |
pob@edu.usp.br||bor@sbpqo.org.br |
_version_ |
1750318320834314240 |