Interstitial and Langerhans' dendritic cells in chronic periodontitis and gingivitis

Detalhes bibliográficos
Autor(a) principal: Cury,Patricia Ramos
Data de Publicação: 2008
Outros Autores: Furuse,Cristiane, Rodrigues,Ana Elisa Amaro, Barbuto,José Alexandre, Araújo,Cavalcanti de, Araújo,Ney Soares de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Oral Research
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242008000300012
Resumo: The aim of the present study was to compare quantitatively the distribution of dendritic cell subpopulations in chronic periodontitis and gingivitis. Fourteen biopsies from patients with chronic periodontitis and fifteen from patients with gingivitis were studied. An immunoperoxidase technique was used to quantify the number of Langerhans' cells (CD1a) and interstitial dendritic cells (factor XIIIa) in the oral and sulcular and junctional/pocket epithelia and in the lamina propria. A greater number of factor XIIIa+ dendritic cells in the lamina propria and CD1a+ dendritic cells in the oral epithelium were observed in gingivitis compared to the periodontitis group (p = 0.05). In the sulcular and junctional/pocket epithelia and in the lamina propria, the number of CD1a+ dendritic cells was similar in the gingivitis and periodontitis groups. In conclusion, the number of Langerhans' cells in the oral epithelium and interstitial dendritic cells in the lamina propria is increased in gingivitis compared to periodontitis, which may contribute to the different pattern of host response in these diseases.
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spelling Interstitial and Langerhans' dendritic cells in chronic periodontitis and gingivitisPeriodontitisGingivitisDendritic cellsCD1aFactor XIIIaThe aim of the present study was to compare quantitatively the distribution of dendritic cell subpopulations in chronic periodontitis and gingivitis. Fourteen biopsies from patients with chronic periodontitis and fifteen from patients with gingivitis were studied. An immunoperoxidase technique was used to quantify the number of Langerhans' cells (CD1a) and interstitial dendritic cells (factor XIIIa) in the oral and sulcular and junctional/pocket epithelia and in the lamina propria. A greater number of factor XIIIa+ dendritic cells in the lamina propria and CD1a+ dendritic cells in the oral epithelium were observed in gingivitis compared to the periodontitis group (p = 0.05). In the sulcular and junctional/pocket epithelia and in the lamina propria, the number of CD1a+ dendritic cells was similar in the gingivitis and periodontitis groups. In conclusion, the number of Langerhans' cells in the oral epithelium and interstitial dendritic cells in the lamina propria is increased in gingivitis compared to periodontitis, which may contribute to the different pattern of host response in these diseases.Sociedade Brasileira de Pesquisa Odontológica - SBPqO2008-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242008000300012Brazilian Oral Research v.22 n.3 2008reponame:Brazilian Oral Researchinstname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)instacron:SBPQO10.1590/S1806-83242008000300012info:eu-repo/semantics/openAccessCury,Patricia RamosFuruse,CristianeRodrigues,Ana Elisa AmaroBarbuto,José AlexandreAraújo,Cavalcanti deAraújo,Ney Soares deeng2009-10-20T00:00:00Zoai:scielo:S1806-83242008000300012Revistahttps://www.scielo.br/j/bor/https://old.scielo.br/oai/scielo-oai.phppob@edu.usp.br||bor@sbpqo.org.br1807-31071806-8324opendoar:2009-10-20T00:00Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)false
dc.title.none.fl_str_mv Interstitial and Langerhans' dendritic cells in chronic periodontitis and gingivitis
title Interstitial and Langerhans' dendritic cells in chronic periodontitis and gingivitis
spellingShingle Interstitial and Langerhans' dendritic cells in chronic periodontitis and gingivitis
Cury,Patricia Ramos
Periodontitis
Gingivitis
Dendritic cells
CD1a
Factor XIIIa
title_short Interstitial and Langerhans' dendritic cells in chronic periodontitis and gingivitis
title_full Interstitial and Langerhans' dendritic cells in chronic periodontitis and gingivitis
title_fullStr Interstitial and Langerhans' dendritic cells in chronic periodontitis and gingivitis
title_full_unstemmed Interstitial and Langerhans' dendritic cells in chronic periodontitis and gingivitis
title_sort Interstitial and Langerhans' dendritic cells in chronic periodontitis and gingivitis
author Cury,Patricia Ramos
author_facet Cury,Patricia Ramos
Furuse,Cristiane
Rodrigues,Ana Elisa Amaro
Barbuto,José Alexandre
Araújo,Cavalcanti de
Araújo,Ney Soares de
author_role author
author2 Furuse,Cristiane
Rodrigues,Ana Elisa Amaro
Barbuto,José Alexandre
Araújo,Cavalcanti de
Araújo,Ney Soares de
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Cury,Patricia Ramos
Furuse,Cristiane
Rodrigues,Ana Elisa Amaro
Barbuto,José Alexandre
Araújo,Cavalcanti de
Araújo,Ney Soares de
dc.subject.por.fl_str_mv Periodontitis
Gingivitis
Dendritic cells
CD1a
Factor XIIIa
topic Periodontitis
Gingivitis
Dendritic cells
CD1a
Factor XIIIa
description The aim of the present study was to compare quantitatively the distribution of dendritic cell subpopulations in chronic periodontitis and gingivitis. Fourteen biopsies from patients with chronic periodontitis and fifteen from patients with gingivitis were studied. An immunoperoxidase technique was used to quantify the number of Langerhans' cells (CD1a) and interstitial dendritic cells (factor XIIIa) in the oral and sulcular and junctional/pocket epithelia and in the lamina propria. A greater number of factor XIIIa+ dendritic cells in the lamina propria and CD1a+ dendritic cells in the oral epithelium were observed in gingivitis compared to the periodontitis group (p = 0.05). In the sulcular and junctional/pocket epithelia and in the lamina propria, the number of CD1a+ dendritic cells was similar in the gingivitis and periodontitis groups. In conclusion, the number of Langerhans' cells in the oral epithelium and interstitial dendritic cells in the lamina propria is increased in gingivitis compared to periodontitis, which may contribute to the different pattern of host response in these diseases.
publishDate 2008
dc.date.none.fl_str_mv 2008-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242008000300012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242008000300012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1806-83242008000300012
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
dc.source.none.fl_str_mv Brazilian Oral Research v.22 n.3 2008
reponame:Brazilian Oral Research
instname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron:SBPQO
instname_str Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron_str SBPQO
institution SBPQO
reponame_str Brazilian Oral Research
collection Brazilian Oral Research
repository.name.fl_str_mv Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
repository.mail.fl_str_mv pob@edu.usp.br||bor@sbpqo.org.br
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