Comparative analysis of preemptive analgesic effect of dexamethasone and diclofenac following third molar surgery
Autor(a) principal: | |
---|---|
Data de Publicação: | 2013 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Oral Research |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242013000300266 |
Resumo: | The objective of the study was to compare the analgesic effectiveness of dexamethasone and diclofenac sodium administered preemptively after surgical removal of third molars. Forty-four ASA (American Society of Anesthesiologists) I patients (19 men, 35 women; 16–28 years old) randomly and double-blindly received diclofenac sodium (50 mg) or dexamethasone (8 mg) or placebo 1 h before surgery. Intensity of pain, measured with a visual analog scale (VAS), was the variable studied at different postoperative times (1 h, 2 h, 3 h, 6 h, 8 h, 12 h, 48 h, 4 d and 7 d). The total amount of rescue medication (TARM) ingested (paracetamol) was another variable of the study. The Kruskal-Wallis statistical test was used. A p value of < .05 was adopted to reject the null hypothesis. The dexamethasone group showed lower pain intensity (p < .05) than the diclofenac sodium and placebo groups (p < .05). No difference in TARM was observed among the groups (p < .05). Preemptively administered, dexamethasone was effective in controlling postoperative pain. |
id |
SBPQO-1_ff96fd063c960254eded240eb6109793 |
---|---|
oai_identifier_str |
oai:scielo:S1806-83242013000300266 |
network_acronym_str |
SBPQO-1 |
network_name_str |
Brazilian Oral Research |
repository_id_str |
|
spelling |
Comparative analysis of preemptive analgesic effect of dexamethasone and diclofenac following third molar surgerySurgery, OralPainRandomized Controlled TrialPain, PostoperativeThe objective of the study was to compare the analgesic effectiveness of dexamethasone and diclofenac sodium administered preemptively after surgical removal of third molars. Forty-four ASA (American Society of Anesthesiologists) I patients (19 men, 35 women; 16–28 years old) randomly and double-blindly received diclofenac sodium (50 mg) or dexamethasone (8 mg) or placebo 1 h before surgery. Intensity of pain, measured with a visual analog scale (VAS), was the variable studied at different postoperative times (1 h, 2 h, 3 h, 6 h, 8 h, 12 h, 48 h, 4 d and 7 d). The total amount of rescue medication (TARM) ingested (paracetamol) was another variable of the study. The Kruskal-Wallis statistical test was used. A p value of < .05 was adopted to reject the null hypothesis. The dexamethasone group showed lower pain intensity (p < .05) than the diclofenac sodium and placebo groups (p < .05). No difference in TARM was observed among the groups (p < .05). Preemptively administered, dexamethasone was effective in controlling postoperative pain.Sociedade Brasileira de Pesquisa Odontológica - SBPqO2013-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242013000300266Brazilian Oral Research v.27 n.3 2013reponame:Brazilian Oral Researchinstname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)instacron:SBPQO10.1590/S1806-83242013005000012info:eu-repo/semantics/openAccessSimone,José LeonardoJorge,Waldyr AntonioHorliana,Anna Carolina Ratto TempestiniCanaval,Talita GirioTortamano,Isabel Peixotoeng2013-05-28T00:00:00Zoai:scielo:S1806-83242013000300266Revistahttps://www.scielo.br/j/bor/https://old.scielo.br/oai/scielo-oai.phppob@edu.usp.br||bor@sbpqo.org.br1807-31071806-8324opendoar:2013-05-28T00:00Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)false |
dc.title.none.fl_str_mv |
Comparative analysis of preemptive analgesic effect of dexamethasone and diclofenac following third molar surgery |
title |
Comparative analysis of preemptive analgesic effect of dexamethasone and diclofenac following third molar surgery |
spellingShingle |
Comparative analysis of preemptive analgesic effect of dexamethasone and diclofenac following third molar surgery Simone,José Leonardo Surgery, Oral Pain Randomized Controlled Trial Pain, Postoperative |
title_short |
Comparative analysis of preemptive analgesic effect of dexamethasone and diclofenac following third molar surgery |
title_full |
Comparative analysis of preemptive analgesic effect of dexamethasone and diclofenac following third molar surgery |
title_fullStr |
Comparative analysis of preemptive analgesic effect of dexamethasone and diclofenac following third molar surgery |
title_full_unstemmed |
Comparative analysis of preemptive analgesic effect of dexamethasone and diclofenac following third molar surgery |
title_sort |
Comparative analysis of preemptive analgesic effect of dexamethasone and diclofenac following third molar surgery |
author |
Simone,José Leonardo |
author_facet |
Simone,José Leonardo Jorge,Waldyr Antonio Horliana,Anna Carolina Ratto Tempestini Canaval,Talita Girio Tortamano,Isabel Peixoto |
author_role |
author |
author2 |
Jorge,Waldyr Antonio Horliana,Anna Carolina Ratto Tempestini Canaval,Talita Girio Tortamano,Isabel Peixoto |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Simone,José Leonardo Jorge,Waldyr Antonio Horliana,Anna Carolina Ratto Tempestini Canaval,Talita Girio Tortamano,Isabel Peixoto |
dc.subject.por.fl_str_mv |
Surgery, Oral Pain Randomized Controlled Trial Pain, Postoperative |
topic |
Surgery, Oral Pain Randomized Controlled Trial Pain, Postoperative |
description |
The objective of the study was to compare the analgesic effectiveness of dexamethasone and diclofenac sodium administered preemptively after surgical removal of third molars. Forty-four ASA (American Society of Anesthesiologists) I patients (19 men, 35 women; 16–28 years old) randomly and double-blindly received diclofenac sodium (50 mg) or dexamethasone (8 mg) or placebo 1 h before surgery. Intensity of pain, measured with a visual analog scale (VAS), was the variable studied at different postoperative times (1 h, 2 h, 3 h, 6 h, 8 h, 12 h, 48 h, 4 d and 7 d). The total amount of rescue medication (TARM) ingested (paracetamol) was another variable of the study. The Kruskal-Wallis statistical test was used. A p value of < .05 was adopted to reject the null hypothesis. The dexamethasone group showed lower pain intensity (p < .05) than the diclofenac sodium and placebo groups (p < .05). No difference in TARM was observed among the groups (p < .05). Preemptively administered, dexamethasone was effective in controlling postoperative pain. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242013000300266 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242013000300266 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1806-83242013005000012 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Pesquisa Odontológica - SBPqO |
publisher.none.fl_str_mv |
Sociedade Brasileira de Pesquisa Odontológica - SBPqO |
dc.source.none.fl_str_mv |
Brazilian Oral Research v.27 n.3 2013 reponame:Brazilian Oral Research instname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO) instacron:SBPQO |
instname_str |
Sociedade Brasileira de Pesquisa Odontológica (SBPqO) |
instacron_str |
SBPQO |
institution |
SBPQO |
reponame_str |
Brazilian Oral Research |
collection |
Brazilian Oral Research |
repository.name.fl_str_mv |
Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO) |
repository.mail.fl_str_mv |
pob@edu.usp.br||bor@sbpqo.org.br |
_version_ |
1750318323469385728 |