Determination of L-aspartic acid by using the Cu(II)-catalyzed oscillating reaction
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of the Brazilian Chemical Society (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009001000009 |
Resumo: | A convenient procedure by means of oscillating chemical system as an analytical tool to determine the L-aspartic acid (L-Asp) is proposed. The system involves the Cu(II)-catalyzed reaction between hydrogen peroxide and sodium thiocyanate in an alkaline medium. The method relies on the linear relationship between the changes in the oscillation period and the logarithm of concentration of L-aspartic acid. Optimized conditions were further validated to ensure the reliability of the method. Under optimum conditions, the calibration plot is linearly proportional to the concentration of L-aspartic acid over the range from 1.17 × 10-5 mol L-1 to 7.10 × 10-8 mol L-1 with a corresponding regression coefficient of 0.9990 (RSD 2.75%). A lower limit of determination (LOD) was 5.58 × 10-8 mol L-1. The proposed method has been used to determine L-aspartic acid in drug sample. Additionally, the HPLC technique was also used to confirm the determination results. |
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Journal of the Brazilian Chemical Society (Online) |
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Determination of L-aspartic acid by using the Cu(II)-catalyzed oscillating reactionoscillating chemical reactionanalyte pulse perturbation techniqueL-aspartic aciddrug sampleA convenient procedure by means of oscillating chemical system as an analytical tool to determine the L-aspartic acid (L-Asp) is proposed. The system involves the Cu(II)-catalyzed reaction between hydrogen peroxide and sodium thiocyanate in an alkaline medium. The method relies on the linear relationship between the changes in the oscillation period and the logarithm of concentration of L-aspartic acid. Optimized conditions were further validated to ensure the reliability of the method. Under optimum conditions, the calibration plot is linearly proportional to the concentration of L-aspartic acid over the range from 1.17 × 10-5 mol L-1 to 7.10 × 10-8 mol L-1 with a corresponding regression coefficient of 0.9990 (RSD 2.75%). A lower limit of determination (LOD) was 5.58 × 10-8 mol L-1. The proposed method has been used to determine L-aspartic acid in drug sample. Additionally, the HPLC technique was also used to confirm the determination results.Sociedade Brasileira de Química2009-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009001000009Journal of the Brazilian Chemical Society v.20 n.10 2009reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532009001000009info:eu-repo/semantics/openAccessGao,JinzhangLv,DongyuSun,HoutanYang,Wueng2011-10-14T00:00:00Zoai:scielo:S0103-50532009001000009Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2011-10-14T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
Determination of L-aspartic acid by using the Cu(II)-catalyzed oscillating reaction |
title |
Determination of L-aspartic acid by using the Cu(II)-catalyzed oscillating reaction |
spellingShingle |
Determination of L-aspartic acid by using the Cu(II)-catalyzed oscillating reaction Gao,Jinzhang oscillating chemical reaction analyte pulse perturbation technique L-aspartic acid drug sample |
title_short |
Determination of L-aspartic acid by using the Cu(II)-catalyzed oscillating reaction |
title_full |
Determination of L-aspartic acid by using the Cu(II)-catalyzed oscillating reaction |
title_fullStr |
Determination of L-aspartic acid by using the Cu(II)-catalyzed oscillating reaction |
title_full_unstemmed |
Determination of L-aspartic acid by using the Cu(II)-catalyzed oscillating reaction |
title_sort |
Determination of L-aspartic acid by using the Cu(II)-catalyzed oscillating reaction |
author |
Gao,Jinzhang |
author_facet |
Gao,Jinzhang Lv,Dongyu Sun,Houtan Yang,Wu |
author_role |
author |
author2 |
Lv,Dongyu Sun,Houtan Yang,Wu |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Gao,Jinzhang Lv,Dongyu Sun,Houtan Yang,Wu |
dc.subject.por.fl_str_mv |
oscillating chemical reaction analyte pulse perturbation technique L-aspartic acid drug sample |
topic |
oscillating chemical reaction analyte pulse perturbation technique L-aspartic acid drug sample |
description |
A convenient procedure by means of oscillating chemical system as an analytical tool to determine the L-aspartic acid (L-Asp) is proposed. The system involves the Cu(II)-catalyzed reaction between hydrogen peroxide and sodium thiocyanate in an alkaline medium. The method relies on the linear relationship between the changes in the oscillation period and the logarithm of concentration of L-aspartic acid. Optimized conditions were further validated to ensure the reliability of the method. Under optimum conditions, the calibration plot is linearly proportional to the concentration of L-aspartic acid over the range from 1.17 × 10-5 mol L-1 to 7.10 × 10-8 mol L-1 with a corresponding regression coefficient of 0.9990 (RSD 2.75%). A lower limit of determination (LOD) was 5.58 × 10-8 mol L-1. The proposed method has been used to determine L-aspartic acid in drug sample. Additionally, the HPLC technique was also used to confirm the determination results. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009001000009 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009001000009 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0103-50532009001000009 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Journal of the Brazilian Chemical Society v.20 n.10 2009 reponame:Journal of the Brazilian Chemical Society (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Journal of the Brazilian Chemical Society (Online) |
collection |
Journal of the Brazilian Chemical Society (Online) |
repository.name.fl_str_mv |
Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
||office@jbcs.sbq.org.br |
_version_ |
1750318170296549376 |