Metal halide hydrates as lewis acid catalysts for the conjugated friedel-crafts reactions of indoles and activated olefins

Detalhes bibliográficos
Autor(a) principal: Schwalm,Cristiane S.
Data de Publicação: 2011
Outros Autores: Ceschi,Marco Antonio, Russowsky,Dennis
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532011000400003
Resumo: Metal halide hydrates such as SnCl2·2H2O, MnCl2·4H2O, SrCl2·6H2O, CrCl2·6H2O, CoCl2·6H2O e CeCl3·7H2O were investigated as mild Lewis acids catalysts for the conjugate Friedel-Crafts reaction between indoles and activated olefins. The reactions were carried out with aliphatic unsaturated ketones over a period of days at room temperature, while chalcones reacted only under reflux conditions. The reactions with nitrostyrenes were either performed in solvent or under solventless conditions. In all cases reasonable to good yields were obtained.
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spelling Metal halide hydrates as lewis acid catalysts for the conjugated friedel-crafts reactions of indoles and activated olefinsFriedel-Craftsindolesactivated olefinsmetal halide hydratesLewis acidsMichael additionMetal halide hydrates such as SnCl2·2H2O, MnCl2·4H2O, SrCl2·6H2O, CrCl2·6H2O, CoCl2·6H2O e CeCl3·7H2O were investigated as mild Lewis acids catalysts for the conjugate Friedel-Crafts reaction between indoles and activated olefins. The reactions were carried out with aliphatic unsaturated ketones over a period of days at room temperature, while chalcones reacted only under reflux conditions. The reactions with nitrostyrenes were either performed in solvent or under solventless conditions. In all cases reasonable to good yields were obtained.Sociedade Brasileira de Química2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532011000400003Journal of the Brazilian Chemical Society v.22 n.4 2011reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532011000400003info:eu-repo/semantics/openAccessSchwalm,Cristiane S.Ceschi,Marco AntonioRussowsky,Denniseng2011-04-14T00:00:00Zoai:scielo:S0103-50532011000400003Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2011-04-14T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Metal halide hydrates as lewis acid catalysts for the conjugated friedel-crafts reactions of indoles and activated olefins
title Metal halide hydrates as lewis acid catalysts for the conjugated friedel-crafts reactions of indoles and activated olefins
spellingShingle Metal halide hydrates as lewis acid catalysts for the conjugated friedel-crafts reactions of indoles and activated olefins
Schwalm,Cristiane S.
Friedel-Crafts
indoles
activated olefins
metal halide hydrates
Lewis acids
Michael addition
title_short Metal halide hydrates as lewis acid catalysts for the conjugated friedel-crafts reactions of indoles and activated olefins
title_full Metal halide hydrates as lewis acid catalysts for the conjugated friedel-crafts reactions of indoles and activated olefins
title_fullStr Metal halide hydrates as lewis acid catalysts for the conjugated friedel-crafts reactions of indoles and activated olefins
title_full_unstemmed Metal halide hydrates as lewis acid catalysts for the conjugated friedel-crafts reactions of indoles and activated olefins
title_sort Metal halide hydrates as lewis acid catalysts for the conjugated friedel-crafts reactions of indoles and activated olefins
author Schwalm,Cristiane S.
author_facet Schwalm,Cristiane S.
Ceschi,Marco Antonio
Russowsky,Dennis
author_role author
author2 Ceschi,Marco Antonio
Russowsky,Dennis
author2_role author
author
dc.contributor.author.fl_str_mv Schwalm,Cristiane S.
Ceschi,Marco Antonio
Russowsky,Dennis
dc.subject.por.fl_str_mv Friedel-Crafts
indoles
activated olefins
metal halide hydrates
Lewis acids
Michael addition
topic Friedel-Crafts
indoles
activated olefins
metal halide hydrates
Lewis acids
Michael addition
description Metal halide hydrates such as SnCl2·2H2O, MnCl2·4H2O, SrCl2·6H2O, CrCl2·6H2O, CoCl2·6H2O e CeCl3·7H2O were investigated as mild Lewis acids catalysts for the conjugate Friedel-Crafts reaction between indoles and activated olefins. The reactions were carried out with aliphatic unsaturated ketones over a period of days at room temperature, while chalcones reacted only under reflux conditions. The reactions with nitrostyrenes were either performed in solvent or under solventless conditions. In all cases reasonable to good yields were obtained.
publishDate 2011
dc.date.none.fl_str_mv 2011-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532011000400003
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532011000400003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532011000400003
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.22 n.4 2011
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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