p-nitrobenzoic acid promoted synthesis of 1,5-benzodiazepine derivatives

Detalhes bibliográficos
Autor(a) principal: Varala,Ravi
Data de Publicação: 2007
Outros Autores: Enugala,Ramu, Adapa,Srinivas R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000200008
Resumo: p-Nitrobenzoic acid was found to be the versatile Bronsted organic acid promoter among the carboxylic acids tested for the preparation of 1,5-benzodiazepine derivatives from a wide range of substituted o-phenylenediamines and ketones. The corresponding products were obtained in good isolated yields (62-92%) under mild conditions using acetonitrile as solvent at ambient temperature. Further, the reagent could be easily recovered and reused.
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spelling p-nitrobenzoic acid promoted synthesis of 1,5-benzodiazepine derivatives1,5-benzodiazepinesbronsted acido-phenylenediamines and ketonesp-nitrobenzoic acidp-Nitrobenzoic acid was found to be the versatile Bronsted organic acid promoter among the carboxylic acids tested for the preparation of 1,5-benzodiazepine derivatives from a wide range of substituted o-phenylenediamines and ketones. The corresponding products were obtained in good isolated yields (62-92%) under mild conditions using acetonitrile as solvent at ambient temperature. Further, the reagent could be easily recovered and reused.Sociedade Brasileira de Química2007-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000200008Journal of the Brazilian Chemical Society v.18 n.2 2007reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532007000200008info:eu-repo/semantics/openAccessVarala,RaviEnugala,RamuAdapa,Srinivas R.eng2007-06-13T00:00:00Zoai:scielo:S0103-50532007000200008Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2007-06-13T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv p-nitrobenzoic acid promoted synthesis of 1,5-benzodiazepine derivatives
title p-nitrobenzoic acid promoted synthesis of 1,5-benzodiazepine derivatives
spellingShingle p-nitrobenzoic acid promoted synthesis of 1,5-benzodiazepine derivatives
Varala,Ravi
1,5-benzodiazepines
bronsted acid
o-phenylenediamines and ketones
p-nitrobenzoic acid
title_short p-nitrobenzoic acid promoted synthesis of 1,5-benzodiazepine derivatives
title_full p-nitrobenzoic acid promoted synthesis of 1,5-benzodiazepine derivatives
title_fullStr p-nitrobenzoic acid promoted synthesis of 1,5-benzodiazepine derivatives
title_full_unstemmed p-nitrobenzoic acid promoted synthesis of 1,5-benzodiazepine derivatives
title_sort p-nitrobenzoic acid promoted synthesis of 1,5-benzodiazepine derivatives
author Varala,Ravi
author_facet Varala,Ravi
Enugala,Ramu
Adapa,Srinivas R.
author_role author
author2 Enugala,Ramu
Adapa,Srinivas R.
author2_role author
author
dc.contributor.author.fl_str_mv Varala,Ravi
Enugala,Ramu
Adapa,Srinivas R.
dc.subject.por.fl_str_mv 1,5-benzodiazepines
bronsted acid
o-phenylenediamines and ketones
p-nitrobenzoic acid
topic 1,5-benzodiazepines
bronsted acid
o-phenylenediamines and ketones
p-nitrobenzoic acid
description p-Nitrobenzoic acid was found to be the versatile Bronsted organic acid promoter among the carboxylic acids tested for the preparation of 1,5-benzodiazepine derivatives from a wide range of substituted o-phenylenediamines and ketones. The corresponding products were obtained in good isolated yields (62-92%) under mild conditions using acetonitrile as solvent at ambient temperature. Further, the reagent could be easily recovered and reused.
publishDate 2007
dc.date.none.fl_str_mv 2007-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000200008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000200008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532007000200008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.18 n.2 2007
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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