Reações aldólicas assimétricas catalíticas

Detalhes bibliográficos
Autor(a) principal: Corrêa Jr.,Ivan R.
Data de Publicação: 2003
Outros Autores: Pilli,Ronaldo A.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422003000400016
Resumo: This review describes the use of catalytic asymmetric aldol reactions of silyl enol ethers and silyl (thio)ketene acetals with aldehydes (the Mukaiyama aldol reaction) in order to illustrate its synthetic utility. A variety of Lewis acid and basic reagents were employed for catalytic aldol reactions with high diastereo- and enantioselectivities. The origins of the selectivity of these reactions are discussed and some representative examples of their application in the synthesis of natural products are presented. New developments in chiral heterobimettalic lanthanoid catalysis and enantioselective aldol reactions in aqueous media are also included.
id SBQ-3_dca4e9387a380494b133255bb4703a7e
oai_identifier_str oai:scielo:S0100-40422003000400016
network_acronym_str SBQ-3
network_name_str Química Nova (Online)
repository_id_str
spelling Reações aldólicas assimétricas catalíticasaldol reactionasymmetric catalysisenantioselective synthesisThis review describes the use of catalytic asymmetric aldol reactions of silyl enol ethers and silyl (thio)ketene acetals with aldehydes (the Mukaiyama aldol reaction) in order to illustrate its synthetic utility. A variety of Lewis acid and basic reagents were employed for catalytic aldol reactions with high diastereo- and enantioselectivities. The origins of the selectivity of these reactions are discussed and some representative examples of their application in the synthesis of natural products are presented. New developments in chiral heterobimettalic lanthanoid catalysis and enantioselective aldol reactions in aqueous media are also included.Sociedade Brasileira de Química2003-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422003000400016Química Nova v.26 n.4 2003reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422003000400016info:eu-repo/semantics/openAccessCorrêa Jr.,Ivan R.Pilli,Ronaldo A.por2003-08-04T00:00:00Zoai:scielo:S0100-40422003000400016Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2003-08-04T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Reações aldólicas assimétricas catalíticas
title Reações aldólicas assimétricas catalíticas
spellingShingle Reações aldólicas assimétricas catalíticas
Corrêa Jr.,Ivan R.
aldol reaction
asymmetric catalysis
enantioselective synthesis
title_short Reações aldólicas assimétricas catalíticas
title_full Reações aldólicas assimétricas catalíticas
title_fullStr Reações aldólicas assimétricas catalíticas
title_full_unstemmed Reações aldólicas assimétricas catalíticas
title_sort Reações aldólicas assimétricas catalíticas
author Corrêa Jr.,Ivan R.
author_facet Corrêa Jr.,Ivan R.
Pilli,Ronaldo A.
author_role author
author2 Pilli,Ronaldo A.
author2_role author
dc.contributor.author.fl_str_mv Corrêa Jr.,Ivan R.
Pilli,Ronaldo A.
dc.subject.por.fl_str_mv aldol reaction
asymmetric catalysis
enantioselective synthesis
topic aldol reaction
asymmetric catalysis
enantioselective synthesis
description This review describes the use of catalytic asymmetric aldol reactions of silyl enol ethers and silyl (thio)ketene acetals with aldehydes (the Mukaiyama aldol reaction) in order to illustrate its synthetic utility. A variety of Lewis acid and basic reagents were employed for catalytic aldol reactions with high diastereo- and enantioselectivities. The origins of the selectivity of these reactions are discussed and some representative examples of their application in the synthesis of natural products are presented. New developments in chiral heterobimettalic lanthanoid catalysis and enantioselective aldol reactions in aqueous media are also included.
publishDate 2003
dc.date.none.fl_str_mv 2003-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422003000400016
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422003000400016
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 10.1590/S0100-40422003000400016
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.26 n.4 2003
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
_version_ 1750318103412080640

Registros relacionados