Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities

Detalhes bibliográficos
Autor(a) principal: Panthong,Kanda
Data de Publicação: 2013
Outros Autores: Tohdee,Kanogwan, Hutadilok-Towatana,Nongporn, Voravuthikunchai,Supayang P., Chusri,Sasitorn
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532013001000014
Resumo: One new prenylated flavone, 2,8-dihydroxy-3,10-dimethoxy-6-(2-methyl-1-propen-1-yl)-6H,7H-[1]benzopyrano[4,3-b][1]-benzopyran-7-one, together with 24 known compounds were isolated from crude acetone extract from the roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer. Their structures were determined by 1D and 2D nuclear magnetic resonance (NMR) spectroscopic data. The antioxidant and antibacterial activities of the isolated compounds were evaluated. The new compound showed potent antioxidant activity against DPPH• and superoxide with IC50 values of 0.033 and 0.125 mg mL-1, respectively. Significant antibacterial activity against Acinetobacter baumannii was observed with MIC value of 50 mg mL-1.
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spelling Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activitiesArtocarpusMoraceaeprenylated flavoneantioxidant activityantibacterial activityOne new prenylated flavone, 2,8-dihydroxy-3,10-dimethoxy-6-(2-methyl-1-propen-1-yl)-6H,7H-[1]benzopyrano[4,3-b][1]-benzopyran-7-one, together with 24 known compounds were isolated from crude acetone extract from the roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer. Their structures were determined by 1D and 2D nuclear magnetic resonance (NMR) spectroscopic data. The antioxidant and antibacterial activities of the isolated compounds were evaluated. The new compound showed potent antioxidant activity against DPPH• and superoxide with IC50 values of 0.033 and 0.125 mg mL-1, respectively. Significant antibacterial activity against Acinetobacter baumannii was observed with MIC value of 50 mg mL-1.Sociedade Brasileira de Química2013-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532013001000014Journal of the Brazilian Chemical Society v.24 n.10 2013reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.5935/0103-5053.20130212info:eu-repo/semantics/openAccessPanthong,KandaTohdee,KanogwanHutadilok-Towatana,NongpornVoravuthikunchai,Supayang P.Chusri,Sasitorneng2015-07-21T00:00:00Zoai:scielo:S0103-50532013001000014Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2015-07-21T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities
title Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities
spellingShingle Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities
Panthong,Kanda
Artocarpus
Moraceae
prenylated flavone
antioxidant activity
antibacterial activity
title_short Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities
title_full Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities
title_fullStr Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities
title_full_unstemmed Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities
title_sort Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities
author Panthong,Kanda
author_facet Panthong,Kanda
Tohdee,Kanogwan
Hutadilok-Towatana,Nongporn
Voravuthikunchai,Supayang P.
Chusri,Sasitorn
author_role author
author2 Tohdee,Kanogwan
Hutadilok-Towatana,Nongporn
Voravuthikunchai,Supayang P.
Chusri,Sasitorn
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Panthong,Kanda
Tohdee,Kanogwan
Hutadilok-Towatana,Nongporn
Voravuthikunchai,Supayang P.
Chusri,Sasitorn
dc.subject.por.fl_str_mv Artocarpus
Moraceae
prenylated flavone
antioxidant activity
antibacterial activity
topic Artocarpus
Moraceae
prenylated flavone
antioxidant activity
antibacterial activity
description One new prenylated flavone, 2,8-dihydroxy-3,10-dimethoxy-6-(2-methyl-1-propen-1-yl)-6H,7H-[1]benzopyrano[4,3-b][1]-benzopyran-7-one, together with 24 known compounds were isolated from crude acetone extract from the roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer. Their structures were determined by 1D and 2D nuclear magnetic resonance (NMR) spectroscopic data. The antioxidant and antibacterial activities of the isolated compounds were evaluated. The new compound showed potent antioxidant activity against DPPH• and superoxide with IC50 values of 0.033 and 0.125 mg mL-1, respectively. Significant antibacterial activity against Acinetobacter baumannii was observed with MIC value of 50 mg mL-1.
publishDate 2013
dc.date.none.fl_str_mv 2013-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532013001000014
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532013001000014
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0103-5053.20130212
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.24 n.10 2013
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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