Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of the Brazilian Chemical Society (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532013001000014 |
Resumo: | One new prenylated flavone, 2,8-dihydroxy-3,10-dimethoxy-6-(2-methyl-1-propen-1-yl)-6H,7H-[1]benzopyrano[4,3-b][1]-benzopyran-7-one, together with 24 known compounds were isolated from crude acetone extract from the roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer. Their structures were determined by 1D and 2D nuclear magnetic resonance (NMR) spectroscopic data. The antioxidant and antibacterial activities of the isolated compounds were evaluated. The new compound showed potent antioxidant activity against DPPH and superoxide with IC50 values of 0.033 and 0.125 mg mL-1, respectively. Significant antibacterial activity against Acinetobacter baumannii was observed with MIC value of 50 mg mL-1. |
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Journal of the Brazilian Chemical Society (Online) |
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Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activitiesArtocarpusMoraceaeprenylated flavoneantioxidant activityantibacterial activityOne new prenylated flavone, 2,8-dihydroxy-3,10-dimethoxy-6-(2-methyl-1-propen-1-yl)-6H,7H-[1]benzopyrano[4,3-b][1]-benzopyran-7-one, together with 24 known compounds were isolated from crude acetone extract from the roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer. Their structures were determined by 1D and 2D nuclear magnetic resonance (NMR) spectroscopic data. The antioxidant and antibacterial activities of the isolated compounds were evaluated. The new compound showed potent antioxidant activity against DPPH and superoxide with IC50 values of 0.033 and 0.125 mg mL-1, respectively. Significant antibacterial activity against Acinetobacter baumannii was observed with MIC value of 50 mg mL-1.Sociedade Brasileira de Química2013-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532013001000014Journal of the Brazilian Chemical Society v.24 n.10 2013reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.5935/0103-5053.20130212info:eu-repo/semantics/openAccessPanthong,KandaTohdee,KanogwanHutadilok-Towatana,NongpornVoravuthikunchai,Supayang P.Chusri,Sasitorneng2015-07-21T00:00:00Zoai:scielo:S0103-50532013001000014Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2015-07-21T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities |
title |
Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities |
spellingShingle |
Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities Panthong,Kanda Artocarpus Moraceae prenylated flavone antioxidant activity antibacterial activity |
title_short |
Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities |
title_full |
Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities |
title_fullStr |
Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities |
title_full_unstemmed |
Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities |
title_sort |
Prenylated flavone from roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer and its biological activities |
author |
Panthong,Kanda |
author_facet |
Panthong,Kanda Tohdee,Kanogwan Hutadilok-Towatana,Nongporn Voravuthikunchai,Supayang P. Chusri,Sasitorn |
author_role |
author |
author2 |
Tohdee,Kanogwan Hutadilok-Towatana,Nongporn Voravuthikunchai,Supayang P. Chusri,Sasitorn |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Panthong,Kanda Tohdee,Kanogwan Hutadilok-Towatana,Nongporn Voravuthikunchai,Supayang P. Chusri,Sasitorn |
dc.subject.por.fl_str_mv |
Artocarpus Moraceae prenylated flavone antioxidant activity antibacterial activity |
topic |
Artocarpus Moraceae prenylated flavone antioxidant activity antibacterial activity |
description |
One new prenylated flavone, 2,8-dihydroxy-3,10-dimethoxy-6-(2-methyl-1-propen-1-yl)-6H,7H-[1]benzopyrano[4,3-b][1]-benzopyran-7-one, together with 24 known compounds were isolated from crude acetone extract from the roots of a hybrid between Artocarpus heterophyllus and Artocarpus integer. Their structures were determined by 1D and 2D nuclear magnetic resonance (NMR) spectroscopic data. The antioxidant and antibacterial activities of the isolated compounds were evaluated. The new compound showed potent antioxidant activity against DPPH and superoxide with IC50 values of 0.033 and 0.125 mg mL-1, respectively. Significant antibacterial activity against Acinetobacter baumannii was observed with MIC value of 50 mg mL-1. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532013001000014 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532013001000014 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.5935/0103-5053.20130212 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Journal of the Brazilian Chemical Society v.24 n.10 2013 reponame:Journal of the Brazilian Chemical Society (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Journal of the Brazilian Chemical Society (Online) |
collection |
Journal of the Brazilian Chemical Society (Online) |
repository.name.fl_str_mv |
Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
||office@jbcs.sbq.org.br |
_version_ |
1750318175302451200 |