Electrochemical determination of oncocalyxone A using an iron-phthalocyanine/iron-porphyrin modified glassy carbon electrode

• Autor(a) principal: Costa,Cicero de O.
• Data de Publicação: 2008
• Outros Autores: Souza,Antonio A. de, Luz,Rita de Cássia S., Lemos,Telma L. G., Pessoa,Otília D. L., Kubota,Lauro T., Goulart,Marília O. F.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Journal of the Brazilian Chemical Society (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000400013
• topic: voltammetric sensor; oncocalyxone; quinone; chemically modified electrodes; catalysis

The development of a highly sensitive voltammetric sensor for oncocalyxone A using a glassy carbon electrode modified with a bilayer iron(II) tetrasulfonated phthalocyanine (FeTSPc) and iron(III) tetra-(N-methyl-4-pyridyl)-porphyrin (FeT4MPyP) is described. The modified electrode showed high catalytic activity and stability for the oncocalyxone A reduction, provoking the anodic shift of the reduction peak potentials of ca. 30 mV and presenting much higher peak currents than those obtained on the bare GC electrode. A wide linear response range between 0.005-1.2 µmol L-1, with a sensitivity of 8.11 µA L µmol-1 and limits of detection (LOD) and quantification (LOQ) of 1.5 and 5 nmol L-1 were obtained with this sensor.