New phenolic glycosides from Phyllanthus cochinchinensis

Detalhes bibliográficos
Autor(a) principal: Zhao,Jian-Qiang
Data de Publicação: 2014
Outros Autores: Wang,Yan-Ming, Lv,Jun-Jiang, Zhu,Hong-Tao, Wang,Dong, Yang,Chong-Ren, Xu,Min, Zhang,Ying-Jun
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532014000800016
Resumo: Chemical investigation of the whole plants of Phyllanthus cochinchinensis (Euphorbiaceae) led to the isolation of three new phenolic glycosides, phyllanthuosides A-C, together with 12 known compounds. Their structures were established on the basis of extensive spectroscopic analysis and chemical methods. Among them, phyllanthuosides A and B are two of the rare phenolic glycosides, featuring with a C6-C3-C6 skeleton. The absolute configurations of phyllanthuosides A and B were established by calculated electric circular dichroism (ECD) using time dependent density functional theory (TDDFT). The isolates were also tested for their cytotoxicity and antimicrobial activity.
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spelling New phenolic glycosides from Phyllanthus cochinchinensisPhyllantus cochinchinensisEuphorbiaceaephenolic glycosidescytotoxicityantimicrobial activityChemical investigation of the whole plants of Phyllanthus cochinchinensis (Euphorbiaceae) led to the isolation of three new phenolic glycosides, phyllanthuosides A-C, together with 12 known compounds. Their structures were established on the basis of extensive spectroscopic analysis and chemical methods. Among them, phyllanthuosides A and B are two of the rare phenolic glycosides, featuring with a C6-C3-C6 skeleton. The absolute configurations of phyllanthuosides A and B were established by calculated electric circular dichroism (ECD) using time dependent density functional theory (TDDFT). The isolates were also tested for their cytotoxicity and antimicrobial activity.Sociedade Brasileira de Química2014-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532014000800016Journal of the Brazilian Chemical Society v.25 n.8 2014reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.5935/0103-5053.20140127info:eu-repo/semantics/openAccessZhao,Jian-QiangWang,Yan-MingLv,Jun-JiangZhu,Hong-TaoWang,DongYang,Chong-RenXu,MinZhang,Ying-Juneng2014-08-04T00:00:00Zoai:scielo:S0103-50532014000800016Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2014-08-04T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv New phenolic glycosides from Phyllanthus cochinchinensis
title New phenolic glycosides from Phyllanthus cochinchinensis
spellingShingle New phenolic glycosides from Phyllanthus cochinchinensis
Zhao,Jian-Qiang
Phyllantus cochinchinensis
Euphorbiaceae
phenolic glycosides
cytotoxicity
antimicrobial activity
title_short New phenolic glycosides from Phyllanthus cochinchinensis
title_full New phenolic glycosides from Phyllanthus cochinchinensis
title_fullStr New phenolic glycosides from Phyllanthus cochinchinensis
title_full_unstemmed New phenolic glycosides from Phyllanthus cochinchinensis
title_sort New phenolic glycosides from Phyllanthus cochinchinensis
author Zhao,Jian-Qiang
author_facet Zhao,Jian-Qiang
Wang,Yan-Ming
Lv,Jun-Jiang
Zhu,Hong-Tao
Wang,Dong
Yang,Chong-Ren
Xu,Min
Zhang,Ying-Jun
author_role author
author2 Wang,Yan-Ming
Lv,Jun-Jiang
Zhu,Hong-Tao
Wang,Dong
Yang,Chong-Ren
Xu,Min
Zhang,Ying-Jun
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Zhao,Jian-Qiang
Wang,Yan-Ming
Lv,Jun-Jiang
Zhu,Hong-Tao
Wang,Dong
Yang,Chong-Ren
Xu,Min
Zhang,Ying-Jun
dc.subject.por.fl_str_mv Phyllantus cochinchinensis
Euphorbiaceae
phenolic glycosides
cytotoxicity
antimicrobial activity
topic Phyllantus cochinchinensis
Euphorbiaceae
phenolic glycosides
cytotoxicity
antimicrobial activity
description Chemical investigation of the whole plants of Phyllanthus cochinchinensis (Euphorbiaceae) led to the isolation of three new phenolic glycosides, phyllanthuosides A-C, together with 12 known compounds. Their structures were established on the basis of extensive spectroscopic analysis and chemical methods. Among them, phyllanthuosides A and B are two of the rare phenolic glycosides, featuring with a C6-C3-C6 skeleton. The absolute configurations of phyllanthuosides A and B were established by calculated electric circular dichroism (ECD) using time dependent density functional theory (TDDFT). The isolates were also tested for their cytotoxicity and antimicrobial activity.
publishDate 2014
dc.date.none.fl_str_mv 2014-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532014000800016
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532014000800016
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0103-5053.20140127
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.25 n.8 2014
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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