Electrospray ionization mass spectrometry screening of piperidine alkaloids from Senna spectabilis (Fabaceae) extracts: fast identification of new constituents and co-metabolites

Detalhes bibliográficos
Autor(a) principal: Pivatto,Marcos
Data de Publicação: 2005
Outros Autores: Crotti,Antônio E. M., Lopes,Norberto P., Castro-Gamboa,Ian, Rezende,Amanda de, Viegas Jr.,Cláudio, Young,Maria Claudia M., Furlan,Maysa, Bolzani,Vanderlan S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000800023
Resumo: The fragmentation pattern of a homologous series of piperidine alkaloids isolated from S. spectabilis was investigated using electrospray ionization tandem mass spectrometry (ESI-MS/MS). The ESI-MS and ESI-MS/MS analyses of EtOH extracts and fractions from flowers and fruits of S. spectabilis allowed to elucidate the structures of four new compounds. The identification of these co-metabolites, based on the fragmentation patterns of previously isolated compounds, and further confirmed by accurate mass spectrometry defines this technique as a powerful tool to determine the "metabolomic profile" of species which has pharmacological importance.
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spelling Electrospray ionization mass spectrometry screening of piperidine alkaloids from Senna spectabilis (Fabaceae) extracts: fast identification of new constituents and co-metabolitesSenna spectabilispiperidine alkaloidsmetabolomic profileelectrospraytandem mass spectrometryThe fragmentation pattern of a homologous series of piperidine alkaloids isolated from S. spectabilis was investigated using electrospray ionization tandem mass spectrometry (ESI-MS/MS). The ESI-MS and ESI-MS/MS analyses of EtOH extracts and fractions from flowers and fruits of S. spectabilis allowed to elucidate the structures of four new compounds. The identification of these co-metabolites, based on the fragmentation patterns of previously isolated compounds, and further confirmed by accurate mass spectrometry defines this technique as a powerful tool to determine the "metabolomic profile" of species which has pharmacological importance.Sociedade Brasileira de Química2005-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000800023Journal of the Brazilian Chemical Society v.16 n.6b 2005reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532005000800023info:eu-repo/semantics/openAccessPivatto,MarcosCrotti,Antônio E. M.Lopes,Norberto P.Castro-Gamboa,IanRezende,Amanda deViegas Jr.,CláudioYoung,Maria Claudia M.Furlan,MaysaBolzani,Vanderlan S.eng2006-01-20T00:00:00Zoai:scielo:S0103-50532005000800023Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2006-01-20T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Electrospray ionization mass spectrometry screening of piperidine alkaloids from Senna spectabilis (Fabaceae) extracts: fast identification of new constituents and co-metabolites
title Electrospray ionization mass spectrometry screening of piperidine alkaloids from Senna spectabilis (Fabaceae) extracts: fast identification of new constituents and co-metabolites
spellingShingle Electrospray ionization mass spectrometry screening of piperidine alkaloids from Senna spectabilis (Fabaceae) extracts: fast identification of new constituents and co-metabolites
Pivatto,Marcos
Senna spectabilis
piperidine alkaloids
metabolomic profile
electrospray
tandem mass spectrometry
title_short Electrospray ionization mass spectrometry screening of piperidine alkaloids from Senna spectabilis (Fabaceae) extracts: fast identification of new constituents and co-metabolites
title_full Electrospray ionization mass spectrometry screening of piperidine alkaloids from Senna spectabilis (Fabaceae) extracts: fast identification of new constituents and co-metabolites
title_fullStr Electrospray ionization mass spectrometry screening of piperidine alkaloids from Senna spectabilis (Fabaceae) extracts: fast identification of new constituents and co-metabolites
title_full_unstemmed Electrospray ionization mass spectrometry screening of piperidine alkaloids from Senna spectabilis (Fabaceae) extracts: fast identification of new constituents and co-metabolites
title_sort Electrospray ionization mass spectrometry screening of piperidine alkaloids from Senna spectabilis (Fabaceae) extracts: fast identification of new constituents and co-metabolites
author Pivatto,Marcos
author_facet Pivatto,Marcos
Crotti,Antônio E. M.
Lopes,Norberto P.
Castro-Gamboa,Ian
Rezende,Amanda de
Viegas Jr.,Cláudio
Young,Maria Claudia M.
Furlan,Maysa
Bolzani,Vanderlan S.
author_role author
author2 Crotti,Antônio E. M.
Lopes,Norberto P.
Castro-Gamboa,Ian
Rezende,Amanda de
Viegas Jr.,Cláudio
Young,Maria Claudia M.
Furlan,Maysa
Bolzani,Vanderlan S.
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pivatto,Marcos
Crotti,Antônio E. M.
Lopes,Norberto P.
Castro-Gamboa,Ian
Rezende,Amanda de
Viegas Jr.,Cláudio
Young,Maria Claudia M.
Furlan,Maysa
Bolzani,Vanderlan S.
dc.subject.por.fl_str_mv Senna spectabilis
piperidine alkaloids
metabolomic profile
electrospray
tandem mass spectrometry
topic Senna spectabilis
piperidine alkaloids
metabolomic profile
electrospray
tandem mass spectrometry
description The fragmentation pattern of a homologous series of piperidine alkaloids isolated from S. spectabilis was investigated using electrospray ionization tandem mass spectrometry (ESI-MS/MS). The ESI-MS and ESI-MS/MS analyses of EtOH extracts and fractions from flowers and fruits of S. spectabilis allowed to elucidate the structures of four new compounds. The identification of these co-metabolites, based on the fragmentation patterns of previously isolated compounds, and further confirmed by accurate mass spectrometry defines this technique as a powerful tool to determine the "metabolomic profile" of species which has pharmacological importance.
publishDate 2005
dc.date.none.fl_str_mv 2005-11-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000800023
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000800023
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532005000800023
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.16 n.6b 2005
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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