Antioxidant Properties of Croton zehntneri Pax et Hoffm. Essential Oil and Its Inclusion Complex with β-Cyclodextrin Prepared by Spray Drying
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of the Brazilian Chemical Society (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532022001001244 |
Resumo: | Croton zehntneri Pax et Hoffm. is a plant from Northeastern Brazil, whose main component of its essential oil is estragole. Its thermal instability and low aqueous solubility prevent its technological application. This study aimed to prepare and characterize the Croton zehntneri essential oil (CZEO) complexed with β-cyclodextrin (β-CD), and to evaluate antioxidant activity of free and complexed-CZEO in vitro systems by the elimination of 2,2-diphenyl-1-picrylhydrazyl radicals (DPPH•), 2,2’-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS•+), hydroxyl and nitric oxide, as well as their ability to transfer electrons by the reducing potential. The infrared spectroscopy and thermal techniques demonstrated the formation of the inclusion complex (Est/β-CD) obtained by spray drying method. The free CZEO and its Est/β-CD at 0.9, 1.8, 3.6, 7.2, 14.4 and 28.8 µg mL-1 showed the ability to remove DPPH• (EC50 (half maximal effective concentration) 26.06 and 9.46 µg mL-1, respectively) and ABTS•+ (EC50 22.73 and 4.47 µg mL-1, respectively), nitric oxide inhibition (EC50 17.65 and 2.68 µg mL-1, respectively), hydroxyl radical sequestration (EC50 23.42 and 2.34 µg mL-1, respectively) and reducing potential (EC50 46.48 and 12.47 µg mL-1, respectively). The formation of the inclusion complex significantly increases its antioxidant potential. |
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Antioxidant Properties of Croton zehntneri Pax et Hoffm. Essential Oil and Its Inclusion Complex with β-Cyclodextrin Prepared by Spray DryingCroton zehntneriestragoleβ-cyclodextrinantioxidant potentialCroton zehntneri Pax et Hoffm. is a plant from Northeastern Brazil, whose main component of its essential oil is estragole. Its thermal instability and low aqueous solubility prevent its technological application. This study aimed to prepare and characterize the Croton zehntneri essential oil (CZEO) complexed with β-cyclodextrin (β-CD), and to evaluate antioxidant activity of free and complexed-CZEO in vitro systems by the elimination of 2,2-diphenyl-1-picrylhydrazyl radicals (DPPH•), 2,2’-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS•+), hydroxyl and nitric oxide, as well as their ability to transfer electrons by the reducing potential. The infrared spectroscopy and thermal techniques demonstrated the formation of the inclusion complex (Est/β-CD) obtained by spray drying method. The free CZEO and its Est/β-CD at 0.9, 1.8, 3.6, 7.2, 14.4 and 28.8 µg mL-1 showed the ability to remove DPPH• (EC50 (half maximal effective concentration) 26.06 and 9.46 µg mL-1, respectively) and ABTS•+ (EC50 22.73 and 4.47 µg mL-1, respectively), nitric oxide inhibition (EC50 17.65 and 2.68 µg mL-1, respectively), hydroxyl radical sequestration (EC50 23.42 and 2.34 µg mL-1, respectively) and reducing potential (EC50 46.48 and 12.47 µg mL-1, respectively). The formation of the inclusion complex significantly increases its antioxidant potential.Sociedade Brasileira de Química2022-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532022001001244Journal of the Brazilian Chemical Society v.33 n.10 2022reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.21577/0103-5053.20220051info:eu-repo/semantics/openAccessSousa,Antônio J. P.Oliveira,George L. S.Fonseca,LorennaRocha,Marcio S.Rai,MahendraSantos,Francisco E. P.Lima,Sidney G. deeng2022-10-07T00:00:00Zoai:scielo:S0103-50532022001001244Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2022-10-07T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
Antioxidant Properties of Croton zehntneri Pax et Hoffm. Essential Oil and Its Inclusion Complex with β-Cyclodextrin Prepared by Spray Drying |
title |
Antioxidant Properties of Croton zehntneri Pax et Hoffm. Essential Oil and Its Inclusion Complex with β-Cyclodextrin Prepared by Spray Drying |
spellingShingle |
Antioxidant Properties of Croton zehntneri Pax et Hoffm. Essential Oil and Its Inclusion Complex with β-Cyclodextrin Prepared by Spray Drying Sousa,Antônio J. P. Croton zehntneri estragole β-cyclodextrin antioxidant potential |
title_short |
Antioxidant Properties of Croton zehntneri Pax et Hoffm. Essential Oil and Its Inclusion Complex with β-Cyclodextrin Prepared by Spray Drying |
title_full |
Antioxidant Properties of Croton zehntneri Pax et Hoffm. Essential Oil and Its Inclusion Complex with β-Cyclodextrin Prepared by Spray Drying |
title_fullStr |
Antioxidant Properties of Croton zehntneri Pax et Hoffm. Essential Oil and Its Inclusion Complex with β-Cyclodextrin Prepared by Spray Drying |
title_full_unstemmed |
Antioxidant Properties of Croton zehntneri Pax et Hoffm. Essential Oil and Its Inclusion Complex with β-Cyclodextrin Prepared by Spray Drying |
title_sort |
Antioxidant Properties of Croton zehntneri Pax et Hoffm. Essential Oil and Its Inclusion Complex with β-Cyclodextrin Prepared by Spray Drying |
author |
Sousa,Antônio J. P. |
author_facet |
Sousa,Antônio J. P. Oliveira,George L. S. Fonseca,Lorenna Rocha,Marcio S. Rai,Mahendra Santos,Francisco E. P. Lima,Sidney G. de |
author_role |
author |
author2 |
Oliveira,George L. S. Fonseca,Lorenna Rocha,Marcio S. Rai,Mahendra Santos,Francisco E. P. Lima,Sidney G. de |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Sousa,Antônio J. P. Oliveira,George L. S. Fonseca,Lorenna Rocha,Marcio S. Rai,Mahendra Santos,Francisco E. P. Lima,Sidney G. de |
dc.subject.por.fl_str_mv |
Croton zehntneri estragole β-cyclodextrin antioxidant potential |
topic |
Croton zehntneri estragole β-cyclodextrin antioxidant potential |
description |
Croton zehntneri Pax et Hoffm. is a plant from Northeastern Brazil, whose main component of its essential oil is estragole. Its thermal instability and low aqueous solubility prevent its technological application. This study aimed to prepare and characterize the Croton zehntneri essential oil (CZEO) complexed with β-cyclodextrin (β-CD), and to evaluate antioxidant activity of free and complexed-CZEO in vitro systems by the elimination of 2,2-diphenyl-1-picrylhydrazyl radicals (DPPH•), 2,2’-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS•+), hydroxyl and nitric oxide, as well as their ability to transfer electrons by the reducing potential. The infrared spectroscopy and thermal techniques demonstrated the formation of the inclusion complex (Est/β-CD) obtained by spray drying method. The free CZEO and its Est/β-CD at 0.9, 1.8, 3.6, 7.2, 14.4 and 28.8 µg mL-1 showed the ability to remove DPPH• (EC50 (half maximal effective concentration) 26.06 and 9.46 µg mL-1, respectively) and ABTS•+ (EC50 22.73 and 4.47 µg mL-1, respectively), nitric oxide inhibition (EC50 17.65 and 2.68 µg mL-1, respectively), hydroxyl radical sequestration (EC50 23.42 and 2.34 µg mL-1, respectively) and reducing potential (EC50 46.48 and 12.47 µg mL-1, respectively). The formation of the inclusion complex significantly increases its antioxidant potential. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532022001001244 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532022001001244 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.21577/0103-5053.20220051 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Journal of the Brazilian Chemical Society v.33 n.10 2022 reponame:Journal of the Brazilian Chemical Society (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Journal of the Brazilian Chemical Society (Online) |
collection |
Journal of the Brazilian Chemical Society (Online) |
repository.name.fl_str_mv |
Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
||office@jbcs.sbq.org.br |
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1750318185016459264 |