Cationic Micellar Precipitation for Simultaneous Preconcentration of Benzimidazole Anthelmintics in Milk Samples by High-Performance Liquid Chromatography
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of the Brazilian Chemical Society (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000500724 |
Resumo: | A method using micellar precipitation process using cationic surfactant cetyltrimethyl ammonium bromide at ambient temperature was investigated for simultaneous determination of benzimidazoles coupled with high-performance liquid chromatography (HPLC) analysis. The studied benzimidazoles was selected as model compounds including thiabendazole, albendazole, mebendazole, and fenbendazole. The experimental parameters affected the extraction efficiency, including the kind and concentration of salt, pH, concentration of CTAB, volume of 1-octanol, and the centrifugation extraction time, was optimized. The optimum extraction condition: 0.030 mol L-1 CTAB, 10% (m/v) NaCl, pH 4.0, 300 µL 1-octanol and centrifugation time 10 min. Under optimum conditions, enrichment factors of between 60 and 90 fold were obtained, leading to lower limit of detection in the range of 0.5-0.7 µg L-1, depending on the analytes. The calibration range of the method was linear over the wide range of 0.5-1000 µg L-1, with correlation coefficients more than 0.999. Finally, the proposed method was successfully applied in the analysis of benzimidazoles in milk samples. |
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Journal of the Brazilian Chemical Society (Online) |
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Cationic Micellar Precipitation for Simultaneous Preconcentration of Benzimidazole Anthelmintics in Milk Samples by High-Performance Liquid Chromatographycationic micellar precipitationHPLCbenzimidazolesextractionA method using micellar precipitation process using cationic surfactant cetyltrimethyl ammonium bromide at ambient temperature was investigated for simultaneous determination of benzimidazoles coupled with high-performance liquid chromatography (HPLC) analysis. The studied benzimidazoles was selected as model compounds including thiabendazole, albendazole, mebendazole, and fenbendazole. The experimental parameters affected the extraction efficiency, including the kind and concentration of salt, pH, concentration of CTAB, volume of 1-octanol, and the centrifugation extraction time, was optimized. The optimum extraction condition: 0.030 mol L-1 CTAB, 10% (m/v) NaCl, pH 4.0, 300 µL 1-octanol and centrifugation time 10 min. Under optimum conditions, enrichment factors of between 60 and 90 fold were obtained, leading to lower limit of detection in the range of 0.5-0.7 µg L-1, depending on the analytes. The calibration range of the method was linear over the wide range of 0.5-1000 µg L-1, with correlation coefficients more than 0.999. Finally, the proposed method was successfully applied in the analysis of benzimidazoles in milk samples.Sociedade Brasileira de Química2017-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000500724Journal of the Brazilian Chemical Society v.28 n.5 2017reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.21577/0103-5053.20160220info:eu-repo/semantics/openAccessVichapong,JitladaSantaladchaiyakit,YanawathSrijaranai,SupalaxBurakham,Rodjanaeng2017-04-12T00:00:00Zoai:scielo:S0103-50532017000500724Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2017-04-12T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
Cationic Micellar Precipitation for Simultaneous Preconcentration of Benzimidazole Anthelmintics in Milk Samples by High-Performance Liquid Chromatography |
title |
Cationic Micellar Precipitation for Simultaneous Preconcentration of Benzimidazole Anthelmintics in Milk Samples by High-Performance Liquid Chromatography |
spellingShingle |
Cationic Micellar Precipitation for Simultaneous Preconcentration of Benzimidazole Anthelmintics in Milk Samples by High-Performance Liquid Chromatography Vichapong,Jitlada cationic micellar precipitation HPLC benzimidazoles extraction |
title_short |
Cationic Micellar Precipitation for Simultaneous Preconcentration of Benzimidazole Anthelmintics in Milk Samples by High-Performance Liquid Chromatography |
title_full |
Cationic Micellar Precipitation for Simultaneous Preconcentration of Benzimidazole Anthelmintics in Milk Samples by High-Performance Liquid Chromatography |
title_fullStr |
Cationic Micellar Precipitation for Simultaneous Preconcentration of Benzimidazole Anthelmintics in Milk Samples by High-Performance Liquid Chromatography |
title_full_unstemmed |
Cationic Micellar Precipitation for Simultaneous Preconcentration of Benzimidazole Anthelmintics in Milk Samples by High-Performance Liquid Chromatography |
title_sort |
Cationic Micellar Precipitation for Simultaneous Preconcentration of Benzimidazole Anthelmintics in Milk Samples by High-Performance Liquid Chromatography |
author |
Vichapong,Jitlada |
author_facet |
Vichapong,Jitlada Santaladchaiyakit,Yanawath Srijaranai,Supalax Burakham,Rodjana |
author_role |
author |
author2 |
Santaladchaiyakit,Yanawath Srijaranai,Supalax Burakham,Rodjana |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Vichapong,Jitlada Santaladchaiyakit,Yanawath Srijaranai,Supalax Burakham,Rodjana |
dc.subject.por.fl_str_mv |
cationic micellar precipitation HPLC benzimidazoles extraction |
topic |
cationic micellar precipitation HPLC benzimidazoles extraction |
description |
A method using micellar precipitation process using cationic surfactant cetyltrimethyl ammonium bromide at ambient temperature was investigated for simultaneous determination of benzimidazoles coupled with high-performance liquid chromatography (HPLC) analysis. The studied benzimidazoles was selected as model compounds including thiabendazole, albendazole, mebendazole, and fenbendazole. The experimental parameters affected the extraction efficiency, including the kind and concentration of salt, pH, concentration of CTAB, volume of 1-octanol, and the centrifugation extraction time, was optimized. The optimum extraction condition: 0.030 mol L-1 CTAB, 10% (m/v) NaCl, pH 4.0, 300 µL 1-octanol and centrifugation time 10 min. Under optimum conditions, enrichment factors of between 60 and 90 fold were obtained, leading to lower limit of detection in the range of 0.5-0.7 µg L-1, depending on the analytes. The calibration range of the method was linear over the wide range of 0.5-1000 µg L-1, with correlation coefficients more than 0.999. Finally, the proposed method was successfully applied in the analysis of benzimidazoles in milk samples. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-05-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000500724 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000500724 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.21577/0103-5053.20160220 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Journal of the Brazilian Chemical Society v.28 n.5 2017 reponame:Journal of the Brazilian Chemical Society (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Journal of the Brazilian Chemical Society (Online) |
collection |
Journal of the Brazilian Chemical Society (Online) |
repository.name.fl_str_mv |
Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
||office@jbcs.sbq.org.br |
_version_ |
1750318179513532416 |