Uncured Polydimethylsiloxane as Binder Agent for Carbon Paste Electrodes: Application to the Quantification of Propranolol

• Autor(a) principal: Araújo,Diele A. G.
• Data de Publicação: 2019
• Outros Autores: Pradela-Filho,Lauro A., Santos,Allyson L. R., Faria,Anizio M., Takeuchi,Regina M., Karimi-Maleh,Hassan, Santos,André L.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Journal of the Brazilian Chemical Society (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532019000901988
• topic: polydimethylsiloxane; voltammetry; drug analysis

This study describes the use of uncured polydimethylsiloxane (PDMS) as a binder agent to prepare carbon paste electrodes (CPEs). A comparative study between the properties of CPEs prepared with PDMS and mineral oil Nujol®, the most common binder agent for CPEs, was carried out. Cyclic voltammetry, electrochemical impedance spectroscopy, and chronoamperometry showed that PDMS-CPEs presented higher electrical conductivity, active electrochemical area, and wider useful potential window compared with Nujol®-CPEs. Moreover, PDMS-CPEs were more stable in aqueous mixtures containing 50% (v/v) of ethanol or methanol than Nujol®-CPEs. PDMS-CPEs have also provided higher sensitivity and lower limit of detection to propranolol than Nujol®-CPE. Therefore, this study demonstrated that PDMS is a promising alternative binder agent able to produce CPEs with superior chemical/electrochemical stability and improved analytical performance.