Interaction between humic substances and metallic ions: a selectivity study of humic substances and their possible therapeutic application

• Autor(a) principal: Santos,Ademir dos
• Data de Publicação: 2007
• Outros Autores: Botero,Wander Gustavo, Bellin,Iramaia Corrêa, Oliveira,Luciana Camargo de, Rocha,Julio Cesar, Mendonça,André Gustavo Ribeiro, Godinho,Antonio Francisco
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Journal of the Brazilian Chemical Society (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000400023
• topic: humic substance; metals; potentially toxic metals; toxicology

The complexation capacity of humic substances extracted from peat samples taken from the Mogi River in Ribeirao Preto, SP, Brazil, was determined using metal ions (Al(III), Pb(II), Cr(VI) and Cd(II)), yielding the following order of affinity: Cr(VI)< Cd(II)<Pb(II)<Al(III). An oral LD50 test showed that these humic substances are nontoxic up to a maximum concentration of 512 mg kg-1. These findings reinforce the possibility of using humic substances as a metal detoxicant.