Modified silica nanoparticles with an Aminonaphthoquinone

Detalhes bibliográficos
Autor(a) principal: Silveira,Gleiciani Q
Data de Publicação: 2011
Outros Autores: Ronconi,Célia M, Vargas,Maria D, San Gil,Rosane A. S, Magalhães,Alvicler
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532011000500021
Resumo: The synthesis and characterization of silica nanoparticles (NPs) covalently modified with an aminonaphthoquinone are reported. The aminopropylsilicagelnaphthoquinone (APSGNQ) was obtained by nucleophilic substitution of 2-methoxy-1,4-naphthoquinone with aminopropylsilicalgel (APSG) NPs. Solid state 13C and 29Si nuclear magnetic resonance spectra confirmed that the naphthoquinone is covalently bonded to APSG. Due to the solubility of APSGNQ in common organic solvents, solution ultraviolet-visible spectroscopy was used to determine the amount of naphthoquinone on the NPs surface (0.56 mmol of incorporated naphthoquinone per gram of APSGNQ) by comparison with the spectrum of 2-aminobutyl-1,4-naphthoquinone (ABNQ). Elemental analysis indicated that about 8% of the surface propylamine remained unreacted in APSGNQ. These multifunctional silica NPs have potential in medical applications.
id SBQ-2_f36e01c70362c8e34f50c9c5844f5ff5
oai_identifier_str oai:scielo:S0103-50532011000500021
network_acronym_str SBQ-2
network_name_str Journal of the Brazilian Chemical Society (Online)
repository_id_str
spelling Modified silica nanoparticles with an Aminonaphthoquinonemultifunctional materialsilica nanoparticlesnaphthoquinonessolid state 13C and 29Si NMRThe synthesis and characterization of silica nanoparticles (NPs) covalently modified with an aminonaphthoquinone are reported. The aminopropylsilicagelnaphthoquinone (APSGNQ) was obtained by nucleophilic substitution of 2-methoxy-1,4-naphthoquinone with aminopropylsilicalgel (APSG) NPs. Solid state 13C and 29Si nuclear magnetic resonance spectra confirmed that the naphthoquinone is covalently bonded to APSG. Due to the solubility of APSGNQ in common organic solvents, solution ultraviolet-visible spectroscopy was used to determine the amount of naphthoquinone on the NPs surface (0.56 mmol of incorporated naphthoquinone per gram of APSGNQ) by comparison with the spectrum of 2-aminobutyl-1,4-naphthoquinone (ABNQ). Elemental analysis indicated that about 8% of the surface propylamine remained unreacted in APSGNQ. These multifunctional silica NPs have potential in medical applications.Sociedade Brasileira de Química2011-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532011000500021Journal of the Brazilian Chemical Society v.22 n.5 2011reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532011000500021info:eu-repo/semantics/openAccessSilveira,Gleiciani QRonconi,Célia MVargas,Maria DSan Gil,Rosane A. SMagalhães,Alviclereng2011-05-16T00:00:00Zoai:scielo:S0103-50532011000500021Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2011-05-16T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Modified silica nanoparticles with an Aminonaphthoquinone
title Modified silica nanoparticles with an Aminonaphthoquinone
spellingShingle Modified silica nanoparticles with an Aminonaphthoquinone
Silveira,Gleiciani Q
multifunctional material
silica nanoparticles
naphthoquinones
solid state 13C and 29Si NMR
title_short Modified silica nanoparticles with an Aminonaphthoquinone
title_full Modified silica nanoparticles with an Aminonaphthoquinone
title_fullStr Modified silica nanoparticles with an Aminonaphthoquinone
title_full_unstemmed Modified silica nanoparticles with an Aminonaphthoquinone
title_sort Modified silica nanoparticles with an Aminonaphthoquinone
author Silveira,Gleiciani Q
author_facet Silveira,Gleiciani Q
Ronconi,Célia M
Vargas,Maria D
San Gil,Rosane A. S
Magalhães,Alvicler
author_role author
author2 Ronconi,Célia M
Vargas,Maria D
San Gil,Rosane A. S
Magalhães,Alvicler
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Silveira,Gleiciani Q
Ronconi,Célia M
Vargas,Maria D
San Gil,Rosane A. S
Magalhães,Alvicler
dc.subject.por.fl_str_mv multifunctional material
silica nanoparticles
naphthoquinones
solid state 13C and 29Si NMR
topic multifunctional material
silica nanoparticles
naphthoquinones
solid state 13C and 29Si NMR
description The synthesis and characterization of silica nanoparticles (NPs) covalently modified with an aminonaphthoquinone are reported. The aminopropylsilicagelnaphthoquinone (APSGNQ) was obtained by nucleophilic substitution of 2-methoxy-1,4-naphthoquinone with aminopropylsilicalgel (APSG) NPs. Solid state 13C and 29Si nuclear magnetic resonance spectra confirmed that the naphthoquinone is covalently bonded to APSG. Due to the solubility of APSGNQ in common organic solvents, solution ultraviolet-visible spectroscopy was used to determine the amount of naphthoquinone on the NPs surface (0.56 mmol of incorporated naphthoquinone per gram of APSGNQ) by comparison with the spectrum of 2-aminobutyl-1,4-naphthoquinone (ABNQ). Elemental analysis indicated that about 8% of the surface propylamine remained unreacted in APSGNQ. These multifunctional silica NPs have potential in medical applications.
publishDate 2011
dc.date.none.fl_str_mv 2011-05-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532011000500021
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532011000500021
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532011000500021
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.22 n.5 2011
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
_version_ 1750318172269969408