Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa

Detalhes bibliográficos
Autor(a) principal: Serrano,Maria Amélia Rodrigues
Data de Publicação: 2011
Outros Autores: Batista,Andrea Nastri de Luca, Bolzani,Vanderlan da Silva, Santos,Luciana de Ávila, Nogueira,Paulo José de Campos, Nunes-de-Souza,Ricardo Luiz, Latif,Abdul, Arfan,Mohammad
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000500015
Resumo: Two alkaloids, erysodine (1) and erysothrine (2) were isolated from the flowers of a Pakistani medicinal plant, Erythrina suberosa. These compounds were investigated for anxiolytic properties, and the results showed significant effect, in an acute oral treatment with 1-2, which were suspended in saline (NaCl 0.9%) plus DMSO 1%, and evaluated in 122 Swiss male mice exposed to two tests of anxiety - the elevated plus-maze (EPM) and the light/dark transition model (LDTM).
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spelling Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosaanxyolitic activityE. suberosaerythrinian alkaloidsTwo alkaloids, erysodine (1) and erysothrine (2) were isolated from the flowers of a Pakistani medicinal plant, Erythrina suberosa. These compounds were investigated for anxiolytic properties, and the results showed significant effect, in an acute oral treatment with 1-2, which were suspended in saline (NaCl 0.9%) plus DMSO 1%, and evaluated in 122 Swiss male mice exposed to two tests of anxiety - the elevated plus-maze (EPM) and the light/dark transition model (LDTM).Sociedade Brasileira de Química2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000500015Química Nova v.34 n.5 2011reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422011000500015info:eu-repo/semantics/openAccessSerrano,Maria Amélia RodriguesBatista,Andrea Nastri de LucaBolzani,Vanderlan da SilvaSantos,Luciana de ÁvilaNogueira,Paulo José de CamposNunes-de-Souza,Ricardo LuizLatif,AbdulArfan,Mohammadeng2011-07-18T00:00:00Zoai:scielo:S0100-40422011000500015Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2011-07-18T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
title Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
spellingShingle Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
Serrano,Maria Amélia Rodrigues
anxyolitic activity
E. suberosa
erythrinian alkaloids
title_short Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
title_full Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
title_fullStr Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
title_full_unstemmed Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
title_sort Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
author Serrano,Maria Amélia Rodrigues
author_facet Serrano,Maria Amélia Rodrigues
Batista,Andrea Nastri de Luca
Bolzani,Vanderlan da Silva
Santos,Luciana de Ávila
Nogueira,Paulo José de Campos
Nunes-de-Souza,Ricardo Luiz
Latif,Abdul
Arfan,Mohammad
author_role author
author2 Batista,Andrea Nastri de Luca
Bolzani,Vanderlan da Silva
Santos,Luciana de Ávila
Nogueira,Paulo José de Campos
Nunes-de-Souza,Ricardo Luiz
Latif,Abdul
Arfan,Mohammad
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Serrano,Maria Amélia Rodrigues
Batista,Andrea Nastri de Luca
Bolzani,Vanderlan da Silva
Santos,Luciana de Ávila
Nogueira,Paulo José de Campos
Nunes-de-Souza,Ricardo Luiz
Latif,Abdul
Arfan,Mohammad
dc.subject.por.fl_str_mv anxyolitic activity
E. suberosa
erythrinian alkaloids
topic anxyolitic activity
E. suberosa
erythrinian alkaloids
description Two alkaloids, erysodine (1) and erysothrine (2) were isolated from the flowers of a Pakistani medicinal plant, Erythrina suberosa. These compounds were investigated for anxiolytic properties, and the results showed significant effect, in an acute oral treatment with 1-2, which were suspended in saline (NaCl 0.9%) plus DMSO 1%, and evaluated in 122 Swiss male mice exposed to two tests of anxiety - the elevated plus-maze (EPM) and the light/dark transition model (LDTM).
publishDate 2011
dc.date.none.fl_str_mv 2011-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000500015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000500015
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-40422011000500015
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.34 n.5 2011
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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