Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa

Detalhes bibliográficos
Autor(a) principal: Serrano, Maria Amélia Rodrigues [UNESP]
Data de Publicação: 2011
Outros Autores: De Luca Batista, Andrea Nastri [UNESP], Da Silva Bolzani, Vanderlan [UNESP], De Ávila Santos, Luciana [UNESP], De Campos Nogueira, Paulo José [UNESP], Nunes-De-Souza, Ricardo Luiz [UNESP], Latif, Abdul, Arfan, Mohammad
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://hdl.handle.net/11449/232020
Resumo: Two alkaloids, erysodine (1) and erysothrine (2) were isolated from the flowers of a Pakistani medicinal plant, Erythrina suberosa. These compounds were investigated for anxiolytic properties, and the results showed significant effect, in an acute oral treatment with 1-2, which were suspended in saline (NaCl 0.9%) plus DMSO 1%, and evaluated in 122 Swiss male mice exposed to two tests of anxiety - the elevated plus-maze (EPM) and the light/dark transition model (LDTM).
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spelling Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosaAnxyolitic activityE. suberosaErythrinian alkaloidsTwo alkaloids, erysodine (1) and erysothrine (2) were isolated from the flowers of a Pakistani medicinal plant, Erythrina suberosa. These compounds were investigated for anxiolytic properties, and the results showed significant effect, in an acute oral treatment with 1-2, which were suspended in saline (NaCl 0.9%) plus DMSO 1%, and evaluated in 122 Swiss male mice exposed to two tests of anxiety - the elevated plus-maze (EPM) and the light/dark transition model (LDTM).Instituto de Química Universidade Estadual Paulista, CP 355, 14801-970 Araraquara - SPFaculdade de Ciências Farmacêuticas Universidade Estadual Paulista, 14801-902 Araraquara - SPInstitute of Chemical Sciences University of Peshawar, PeshawarInstituto de Química Universidade Estadual Paulista, CP 355, 14801-970 Araraquara - SPFaculdade de Ciências Farmacêuticas Universidade Estadual Paulista, 14801-902 Araraquara - SPUniversidade Estadual Paulista (UNESP)University of PeshawarSerrano, Maria Amélia Rodrigues [UNESP]De Luca Batista, Andrea Nastri [UNESP]Da Silva Bolzani, Vanderlan [UNESP]De Ávila Santos, Luciana [UNESP]De Campos Nogueira, Paulo José [UNESP]Nunes-De-Souza, Ricardo Luiz [UNESP]Latif, AbdulArfan, Mohammad2022-04-29T08:48:43Z2022-04-29T08:48:43Z2011-08-05info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article808-811Quimica Nova, v. 34, n. 5, p. 808-811, 2011.0100-40421678-7064http://hdl.handle.net/11449/2320202-s2.0-79960993898Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengQuimica Novainfo:eu-repo/semantics/openAccess2024-06-24T14:52:02Zoai:repositorio.unesp.br:11449/232020Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:51:12.628013Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
title Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
spellingShingle Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
Serrano, Maria Amélia Rodrigues [UNESP]
Anxyolitic activity
E. suberosa
Erythrinian alkaloids
title_short Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
title_full Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
title_fullStr Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
title_full_unstemmed Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
title_sort Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
author Serrano, Maria Amélia Rodrigues [UNESP]
author_facet Serrano, Maria Amélia Rodrigues [UNESP]
De Luca Batista, Andrea Nastri [UNESP]
Da Silva Bolzani, Vanderlan [UNESP]
De Ávila Santos, Luciana [UNESP]
De Campos Nogueira, Paulo José [UNESP]
Nunes-De-Souza, Ricardo Luiz [UNESP]
Latif, Abdul
Arfan, Mohammad
author_role author
author2 De Luca Batista, Andrea Nastri [UNESP]
Da Silva Bolzani, Vanderlan [UNESP]
De Ávila Santos, Luciana [UNESP]
De Campos Nogueira, Paulo José [UNESP]
Nunes-De-Souza, Ricardo Luiz [UNESP]
Latif, Abdul
Arfan, Mohammad
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
University of Peshawar
dc.contributor.author.fl_str_mv Serrano, Maria Amélia Rodrigues [UNESP]
De Luca Batista, Andrea Nastri [UNESP]
Da Silva Bolzani, Vanderlan [UNESP]
De Ávila Santos, Luciana [UNESP]
De Campos Nogueira, Paulo José [UNESP]
Nunes-De-Souza, Ricardo Luiz [UNESP]
Latif, Abdul
Arfan, Mohammad
dc.subject.por.fl_str_mv Anxyolitic activity
E. suberosa
Erythrinian alkaloids
topic Anxyolitic activity
E. suberosa
Erythrinian alkaloids
description Two alkaloids, erysodine (1) and erysothrine (2) were isolated from the flowers of a Pakistani medicinal plant, Erythrina suberosa. These compounds were investigated for anxiolytic properties, and the results showed significant effect, in an acute oral treatment with 1-2, which were suspended in saline (NaCl 0.9%) plus DMSO 1%, and evaluated in 122 Swiss male mice exposed to two tests of anxiety - the elevated plus-maze (EPM) and the light/dark transition model (LDTM).
publishDate 2011
dc.date.none.fl_str_mv 2011-08-05
2022-04-29T08:48:43Z
2022-04-29T08:48:43Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv Quimica Nova, v. 34, n. 5, p. 808-811, 2011.
0100-4042
1678-7064
http://hdl.handle.net/11449/232020
2-s2.0-79960993898
identifier_str_mv Quimica Nova, v. 34, n. 5, p. 808-811, 2011.
0100-4042
1678-7064
2-s2.0-79960993898
url http://hdl.handle.net/11449/232020
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Quimica Nova
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 808-811
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808129366541991936

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