Modelos estereoquímicos de adição à carbonila

Detalhes bibliográficos
Autor(a) principal: Martins,Bruna S.
Data de Publicação: 2017
Outros Autores: Lüdtke,Diogo S., Moro,Angélica Venturini
Tipo de documento: Artigo
Idioma: por
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422017000300342
Resumo: The stereochemical control in the generation of new stereogenic centers is of paramount importance in organic chemistry. In this context, diastereoselective additions to carbonyl compounds bearing a stereogenic center at the α-position are of particular importance, since an increase in molecular complexity can be achieved by constructing a new bond, together with the introduction of a new stereocenter. Despite the relevance of the topic, it is discussed only briefly in several of the most popular organic chemistry textbooks, or not discussed at all. The present article intends to discuss the evolution of stereochemical models for 1,2-induction and present to students a tool to understand and predict the stereochemical outcome of addition of nucleophiles to aldehydes and ketones bearing a stereogenic center at the α-position.
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spelling Modelos estereoquímicos de adição à carbonilastereochemistrydiastereoselectivitycarbonyl compoundsFelkin-AnhCram-chelateThe stereochemical control in the generation of new stereogenic centers is of paramount importance in organic chemistry. In this context, diastereoselective additions to carbonyl compounds bearing a stereogenic center at the α-position are of particular importance, since an increase in molecular complexity can be achieved by constructing a new bond, together with the introduction of a new stereocenter. Despite the relevance of the topic, it is discussed only briefly in several of the most popular organic chemistry textbooks, or not discussed at all. The present article intends to discuss the evolution of stereochemical models for 1,2-induction and present to students a tool to understand and predict the stereochemical outcome of addition of nucleophiles to aldehydes and ketones bearing a stereogenic center at the α-position.Sociedade Brasileira de Química2017-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422017000300342Química Nova v.40 n.3 2017reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.21577/0100-4042.20160186info:eu-repo/semantics/openAccessMartins,Bruna S.Lüdtke,Diogo S.Moro,Angélica Venturinipor2017-05-05T00:00:00Zoai:scielo:S0100-40422017000300342Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2017-05-05T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Modelos estereoquímicos de adição à carbonila
title Modelos estereoquímicos de adição à carbonila
spellingShingle Modelos estereoquímicos de adição à carbonila
Martins,Bruna S.
stereochemistry
diastereoselectivity
carbonyl compounds
Felkin-Anh
Cram-chelate
title_short Modelos estereoquímicos de adição à carbonila
title_full Modelos estereoquímicos de adição à carbonila
title_fullStr Modelos estereoquímicos de adição à carbonila
title_full_unstemmed Modelos estereoquímicos de adição à carbonila
title_sort Modelos estereoquímicos de adição à carbonila
author Martins,Bruna S.
author_facet Martins,Bruna S.
Lüdtke,Diogo S.
Moro,Angélica Venturini
author_role author
author2 Lüdtke,Diogo S.
Moro,Angélica Venturini
author2_role author
author
dc.contributor.author.fl_str_mv Martins,Bruna S.
Lüdtke,Diogo S.
Moro,Angélica Venturini
dc.subject.por.fl_str_mv stereochemistry
diastereoselectivity
carbonyl compounds
Felkin-Anh
Cram-chelate
topic stereochemistry
diastereoselectivity
carbonyl compounds
Felkin-Anh
Cram-chelate
description The stereochemical control in the generation of new stereogenic centers is of paramount importance in organic chemistry. In this context, diastereoselective additions to carbonyl compounds bearing a stereogenic center at the α-position are of particular importance, since an increase in molecular complexity can be achieved by constructing a new bond, together with the introduction of a new stereocenter. Despite the relevance of the topic, it is discussed only briefly in several of the most popular organic chemistry textbooks, or not discussed at all. The present article intends to discuss the evolution of stereochemical models for 1,2-induction and present to students a tool to understand and predict the stereochemical outcome of addition of nucleophiles to aldehydes and ketones bearing a stereogenic center at the α-position.
publishDate 2017
dc.date.none.fl_str_mv 2017-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422017000300342
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422017000300342
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 10.21577/0100-4042.20160186
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.40 n.3 2017
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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