Determinação rápida de hidroquinona usando análise por injeção em batelada (BIA) com detecção amperométrica

• Autor(a) principal: Cunha,Rafael Rodrigues
• Data de Publicação: 2013
• Outros Autores: Tormin,Thiago Faria, Richter,Eduardo Mathias, Munoz,Rodrigo Alejandro Abarza
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Química Nova (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422013000500009
• topic: amperometry; BIA; boron-doped diamond (BDD)

A fast analytical method for determination of hydroquinone in pharmaceutical formulations employing batch injection analysis (BIA) with amperometric detection using a boron-doped diamond electrode is described. The supporting electrolyte was a 0.1 mol L-1 H2SO4 solution (the single reagent used for analysis). The method showed good repeatability (RSD of 0.45%, n=20), wide linear range (from 10 to 2000 µmol L-1, R=0.9999), low detection limit (0.016 µmol L-1) and satisfactory recovery values (91-96%). Accuracy of the method was evaluated by comparative analyses using high-performance liquid-chromatography. The ability to replace the electronic pipette by disposable syringes (injection procedure) in BIA systems was also shown.