A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações

Detalhes bibliográficos
Autor(a) principal: Freitas,Luiza Baptista de Oliveira
Data de Publicação: 2011
Outros Autores: Ruela,Fernando Armini, Pereira,Guilherme Rocha, Alves,Rosemeire Brondi, Freitas,Rossimiriam Pereira de, Santos,Leandro José dos
Tipo de documento: Artigo
Idioma: por
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011001000012
Resumo: The Copper-catalyzed azide-alkyne cycloaddition (CuAAC), often referred to as "click" reaction, has become a very popular reaction in the last years. It affords exclusively 1,4-disubstituted 1,2,3-triazoles and has been widely used to connect readily accessible building blocks containing various functional groups. The great success of this reaction is based on the fact that it is general, virtually quantitative and very robuste. The scope of this copper-catalyzed synthesis is extraordinary and the reaction has found numerous applications in many research fields, including biological chemistry and materials science. In this review, the main chemical aspects and applications of the "click" reaction in the synthesis of 1,2,3-triazoles are presented.
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spelling A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicaçõesclickreactioncycloadditiontriazoleThe Copper-catalyzed azide-alkyne cycloaddition (CuAAC), often referred to as "click" reaction, has become a very popular reaction in the last years. It affords exclusively 1,4-disubstituted 1,2,3-triazoles and has been widely used to connect readily accessible building blocks containing various functional groups. The great success of this reaction is based on the fact that it is general, virtually quantitative and very robuste. The scope of this copper-catalyzed synthesis is extraordinary and the reaction has found numerous applications in many research fields, including biological chemistry and materials science. In this review, the main chemical aspects and applications of the "click" reaction in the synthesis of 1,2,3-triazoles are presented.Sociedade Brasileira de Química2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011001000012Química Nova v.34 n.10 2011reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422011001000012info:eu-repo/semantics/openAccessFreitas,Luiza Baptista de OliveiraRuela,Fernando ArminiPereira,Guilherme RochaAlves,Rosemeire BrondiFreitas,Rossimiriam Pereira deSantos,Leandro José dospor2011-12-06T00:00:00Zoai:scielo:S0100-40422011001000012Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2011-12-06T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações
title A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações
spellingShingle A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações
Freitas,Luiza Baptista de Oliveira
click
reaction
cycloaddition
triazole
title_short A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações
title_full A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações
title_fullStr A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações
title_full_unstemmed A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações
title_sort A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações
author Freitas,Luiza Baptista de Oliveira
author_facet Freitas,Luiza Baptista de Oliveira
Ruela,Fernando Armini
Pereira,Guilherme Rocha
Alves,Rosemeire Brondi
Freitas,Rossimiriam Pereira de
Santos,Leandro José dos
author_role author
author2 Ruela,Fernando Armini
Pereira,Guilherme Rocha
Alves,Rosemeire Brondi
Freitas,Rossimiriam Pereira de
Santos,Leandro José dos
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Freitas,Luiza Baptista de Oliveira
Ruela,Fernando Armini
Pereira,Guilherme Rocha
Alves,Rosemeire Brondi
Freitas,Rossimiriam Pereira de
Santos,Leandro José dos
dc.subject.por.fl_str_mv click
reaction
cycloaddition
triazole
topic click
reaction
cycloaddition
triazole
description The Copper-catalyzed azide-alkyne cycloaddition (CuAAC), often referred to as "click" reaction, has become a very popular reaction in the last years. It affords exclusively 1,4-disubstituted 1,2,3-triazoles and has been widely used to connect readily accessible building blocks containing various functional groups. The great success of this reaction is based on the fact that it is general, virtually quantitative and very robuste. The scope of this copper-catalyzed synthesis is extraordinary and the reaction has found numerous applications in many research fields, including biological chemistry and materials science. In this review, the main chemical aspects and applications of the "click" reaction in the synthesis of 1,2,3-triazoles are presented.
publishDate 2011
dc.date.none.fl_str_mv 2011-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011001000012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011001000012
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 10.1590/S0100-40422011001000012
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.34 n.10 2011
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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