AMPc - Sinalização intracelular: um software educacional

• Autor(a) principal: Yokaichiya,Daniela K.
• Data de Publicação: 2004
• Outros Autores: Fraceto,Leonardo F., Miranda,Márcio A., Galembeck,Eduardo, Torres,Bayardo B.
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Química Nova (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422004000300020
• topic: AMPc; educational software; intracelular signaling

Chemicals binding to membrane receptors may induce events within the cell changing its behavior. Since these events are simultaneous and hard to be understood by students, we developed a computational model to dynamically and visually explore the cAMP signaling system to facilitate its understanding. The animation is shown in parts, from the hormone-receptor binding to the cellular response. There are some questions to be answered after using the model. The software was field-tested and an evaluation questionnaire (concerning usability, animations, models, and the software as an educational tool) was answered by the students, showing the software to be a valuable aid for content comprehension.