Rotenoids from Tephrosia toxicaria with larvicidal activity against Aedes aegypti, the main vector of dengue fever

Detalhes bibliográficos
Autor(a) principal: Vasconcelos,Jackson Nunes e
Data de Publicação: 2012
Outros Autores: Santiago,Gilvandete Maria Pinheiro, Lima,Jefferson Queiroz, Mafezoli,Jair, Lemos,Telma Leda Gomes de, Silva,Francisca Renata Lopes da, Lima,Mary Anne Sousa, Pimenta,Antônia Torres Ávila, Braz-Filho,Raimundo, Arriaga,Angela Martha Campos, Cesarin-Sobrinho,Dari
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000600005
Resumo: In the search for new larvicides from plants, we have investigated the potential activity of the rotenoids deguelin (1), 12a-hydroxy-α-toxicarol (2) and tephrosin (3), isolated from the bioactive ethanol extract of roots of Tephrosia toxicaria Pers., against Aedes aegypti, the main vector of dengue. The absolute configuration of these compounds was determined by circular dichroism (CD) spectra. The LC50 values of the compounds evaluated justify the potential of T. toxicaria as a new natural larvicide.
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spelling Rotenoids from Tephrosia toxicaria with larvicidal activity against Aedes aegypti, the main vector of dengue feverTephrosia toxicariarotenoidsAedes aegyptiIn the search for new larvicides from plants, we have investigated the potential activity of the rotenoids deguelin (1), 12a-hydroxy-α-toxicarol (2) and tephrosin (3), isolated from the bioactive ethanol extract of roots of Tephrosia toxicaria Pers., against Aedes aegypti, the main vector of dengue. The absolute configuration of these compounds was determined by circular dichroism (CD) spectra. The LC50 values of the compounds evaluated justify the potential of T. toxicaria as a new natural larvicide.Sociedade Brasileira de Química2012-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000600005Química Nova v.35 n.6 2012reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422012000600005info:eu-repo/semantics/openAccessVasconcelos,Jackson Nunes eSantiago,Gilvandete Maria PinheiroLima,Jefferson QueirozMafezoli,JairLemos,Telma Leda Gomes deSilva,Francisca Renata Lopes daLima,Mary Anne SousaPimenta,Antônia Torres ÁvilaBraz-Filho,RaimundoArriaga,Angela Martha CamposCesarin-Sobrinho,Darieng2012-07-25T00:00:00Zoai:scielo:S0100-40422012000600005Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2012-07-25T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Rotenoids from Tephrosia toxicaria with larvicidal activity against Aedes aegypti, the main vector of dengue fever
title Rotenoids from Tephrosia toxicaria with larvicidal activity against Aedes aegypti, the main vector of dengue fever
spellingShingle Rotenoids from Tephrosia toxicaria with larvicidal activity against Aedes aegypti, the main vector of dengue fever
Vasconcelos,Jackson Nunes e
Tephrosia toxicaria
rotenoids
Aedes aegypti
title_short Rotenoids from Tephrosia toxicaria with larvicidal activity against Aedes aegypti, the main vector of dengue fever
title_full Rotenoids from Tephrosia toxicaria with larvicidal activity against Aedes aegypti, the main vector of dengue fever
title_fullStr Rotenoids from Tephrosia toxicaria with larvicidal activity against Aedes aegypti, the main vector of dengue fever
title_full_unstemmed Rotenoids from Tephrosia toxicaria with larvicidal activity against Aedes aegypti, the main vector of dengue fever
title_sort Rotenoids from Tephrosia toxicaria with larvicidal activity against Aedes aegypti, the main vector of dengue fever
author Vasconcelos,Jackson Nunes e
author_facet Vasconcelos,Jackson Nunes e
Santiago,Gilvandete Maria Pinheiro
Lima,Jefferson Queiroz
Mafezoli,Jair
Lemos,Telma Leda Gomes de
Silva,Francisca Renata Lopes da
Lima,Mary Anne Sousa
Pimenta,Antônia Torres Ávila
Braz-Filho,Raimundo
Arriaga,Angela Martha Campos
Cesarin-Sobrinho,Dari
author_role author
author2 Santiago,Gilvandete Maria Pinheiro
Lima,Jefferson Queiroz
Mafezoli,Jair
Lemos,Telma Leda Gomes de
Silva,Francisca Renata Lopes da
Lima,Mary Anne Sousa
Pimenta,Antônia Torres Ávila
Braz-Filho,Raimundo
Arriaga,Angela Martha Campos
Cesarin-Sobrinho,Dari
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Vasconcelos,Jackson Nunes e
Santiago,Gilvandete Maria Pinheiro
Lima,Jefferson Queiroz
Mafezoli,Jair
Lemos,Telma Leda Gomes de
Silva,Francisca Renata Lopes da
Lima,Mary Anne Sousa
Pimenta,Antônia Torres Ávila
Braz-Filho,Raimundo
Arriaga,Angela Martha Campos
Cesarin-Sobrinho,Dari
dc.subject.por.fl_str_mv Tephrosia toxicaria
rotenoids
Aedes aegypti
topic Tephrosia toxicaria
rotenoids
Aedes aegypti
description In the search for new larvicides from plants, we have investigated the potential activity of the rotenoids deguelin (1), 12a-hydroxy-α-toxicarol (2) and tephrosin (3), isolated from the bioactive ethanol extract of roots of Tephrosia toxicaria Pers., against Aedes aegypti, the main vector of dengue. The absolute configuration of these compounds was determined by circular dichroism (CD) spectra. The LC50 values of the compounds evaluated justify the potential of T. toxicaria as a new natural larvicide.
publishDate 2012
dc.date.none.fl_str_mv 2012-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000600005
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000600005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-40422012000600005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.35 n.6 2012
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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