Correlation of anti-inflammatory activity with phenolic content in the leaves of syzygium cumini (l.) skeels (myrtaceae)

Detalhes bibliográficos
Autor(a) principal: Lima,Lucilene Azevedo
Data de Publicação: 2007
Outros Autores: Siani,Antonio Carlos, Brito,Fabíola Almeida, Sampaio,André Luís Franco, Henriques,Maria das Graças Müller Oliveira, Riehl,Carlos Alberto da Silva
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000400019
Resumo: Phenolic contents of extracts of Syzygium cumini leaves, collected monthly over a one-year period, were quantitatively determined by the modified Folin-Ciocalteau method. Extracts and tannin-free fractions were assayed by their potential to inhibit mouse paw edema induced by C48/80. HPLC showed high molecular weight phenolic species and flavonoids in the active extracts and fractions. The highest total phenolic content corresponded to the most potent degree of inhibition and the flavonoids were supposed to be the main species responsible for the activity, given that the flavonoid-enriched ethyl-acetate fraction maintained its effect down to a dose of 0.01 mg/kg in a dose-response manner.
id SBQ-3_a83d7dc8ac4ba812d8ccd2cfb869c718
oai_identifier_str oai:scielo:S0100-40422007000400019
network_acronym_str SBQ-3
network_name_str Química Nova (Online)
repository_id_str
spelling Correlation of anti-inflammatory activity with phenolic content in the leaves of syzygium cumini (l.) skeels (myrtaceae)Syzygium cuminseasonal variationanti-inflammatoryPhenolic contents of extracts of Syzygium cumini leaves, collected monthly over a one-year period, were quantitatively determined by the modified Folin-Ciocalteau method. Extracts and tannin-free fractions were assayed by their potential to inhibit mouse paw edema induced by C48/80. HPLC showed high molecular weight phenolic species and flavonoids in the active extracts and fractions. The highest total phenolic content corresponded to the most potent degree of inhibition and the flavonoids were supposed to be the main species responsible for the activity, given that the flavonoid-enriched ethyl-acetate fraction maintained its effect down to a dose of 0.01 mg/kg in a dose-response manner.Sociedade Brasileira de Química2007-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000400019Química Nova v.30 n.4 2007reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422007000400019info:eu-repo/semantics/openAccessLima,Lucilene AzevedoSiani,Antonio CarlosBrito,Fabíola AlmeidaSampaio,André Luís FrancoHenriques,Maria das Graças Müller OliveiraRiehl,Carlos Alberto da Silvaeng2007-08-10T00:00:00Zoai:scielo:S0100-40422007000400019Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2007-08-10T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Correlation of anti-inflammatory activity with phenolic content in the leaves of syzygium cumini (l.) skeels (myrtaceae)
title Correlation of anti-inflammatory activity with phenolic content in the leaves of syzygium cumini (l.) skeels (myrtaceae)
spellingShingle Correlation of anti-inflammatory activity with phenolic content in the leaves of syzygium cumini (l.) skeels (myrtaceae)
Lima,Lucilene Azevedo
Syzygium cumin
seasonal variation
anti-inflammatory
title_short Correlation of anti-inflammatory activity with phenolic content in the leaves of syzygium cumini (l.) skeels (myrtaceae)
title_full Correlation of anti-inflammatory activity with phenolic content in the leaves of syzygium cumini (l.) skeels (myrtaceae)
title_fullStr Correlation of anti-inflammatory activity with phenolic content in the leaves of syzygium cumini (l.) skeels (myrtaceae)
title_full_unstemmed Correlation of anti-inflammatory activity with phenolic content in the leaves of syzygium cumini (l.) skeels (myrtaceae)
title_sort Correlation of anti-inflammatory activity with phenolic content in the leaves of syzygium cumini (l.) skeels (myrtaceae)
author Lima,Lucilene Azevedo
author_facet Lima,Lucilene Azevedo
Siani,Antonio Carlos
Brito,Fabíola Almeida
Sampaio,André Luís Franco
Henriques,Maria das Graças Müller Oliveira
Riehl,Carlos Alberto da Silva
author_role author
author2 Siani,Antonio Carlos
Brito,Fabíola Almeida
Sampaio,André Luís Franco
Henriques,Maria das Graças Müller Oliveira
Riehl,Carlos Alberto da Silva
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Lima,Lucilene Azevedo
Siani,Antonio Carlos
Brito,Fabíola Almeida
Sampaio,André Luís Franco
Henriques,Maria das Graças Müller Oliveira
Riehl,Carlos Alberto da Silva
dc.subject.por.fl_str_mv Syzygium cumin
seasonal variation
anti-inflammatory
topic Syzygium cumin
seasonal variation
anti-inflammatory
description Phenolic contents of extracts of Syzygium cumini leaves, collected monthly over a one-year period, were quantitatively determined by the modified Folin-Ciocalteau method. Extracts and tannin-free fractions were assayed by their potential to inhibit mouse paw edema induced by C48/80. HPLC showed high molecular weight phenolic species and flavonoids in the active extracts and fractions. The highest total phenolic content corresponded to the most potent degree of inhibition and the flavonoids were supposed to be the main species responsible for the activity, given that the flavonoid-enriched ethyl-acetate fraction maintained its effect down to a dose of 0.01 mg/kg in a dose-response manner.
publishDate 2007
dc.date.none.fl_str_mv 2007-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000400019
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000400019
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-40422007000400019
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.30 n.4 2007
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
_version_ 1750318106450853888

Registros relacionados