In vitro study of antioxidant and scavenger properties of phenolic compounds from Lychnophora species

Detalhes bibliográficos
Autor(a) principal: Grael,Cristiane F. F.
Data de Publicação: 2010
Outros Autores: Kanashiro,Alexandre, Kabeya,Luciana M., Jordão,Christiane O., Takeara,Renata, Gobbo-Neto,Leonardo, Polizello,Ana Cristina M., Lucisano-Valim,Yara M., Lopes,Norberto P., Lopes,João Luis C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010000400019
Resumo: This paper describes the antioxidant effects of thirteen phenolic compounds isolated from plants of the genus Lychnophora. Two assays were performed to evaluate these effects: a cellular test that measured the luminol-enhanced chemiluminescence produced by neutrophils stimulated with opsonized zymosan and a cell-free test involving horseradish peroxidase-H2O2-luminol. In both assays, the antioxidant activity of the phenolic compounds was dependent on their concentration and chemical structure. Our results suggest that the ability of phenolic compounds from Lychnophora species to scavenge and inhibit the generation of ROS may be a mechanism underlying the anti-inflammatory activity of extracts from Lychnophora spp.
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spelling In vitro study of antioxidant and scavenger properties of phenolic compounds from Lychnophora speciesantioxidant activityLychnophoraflavonoidsThis paper describes the antioxidant effects of thirteen phenolic compounds isolated from plants of the genus Lychnophora. Two assays were performed to evaluate these effects: a cellular test that measured the luminol-enhanced chemiluminescence produced by neutrophils stimulated with opsonized zymosan and a cell-free test involving horseradish peroxidase-H2O2-luminol. In both assays, the antioxidant activity of the phenolic compounds was dependent on their concentration and chemical structure. Our results suggest that the ability of phenolic compounds from Lychnophora species to scavenge and inhibit the generation of ROS may be a mechanism underlying the anti-inflammatory activity of extracts from Lychnophora spp.Sociedade Brasileira de Química2010-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010000400019Química Nova v.33 n.4 2010reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422010000400019info:eu-repo/semantics/openAccessGrael,Cristiane F. F.Kanashiro,AlexandreKabeya,Luciana M.Jordão,Christiane O.Takeara,RenataGobbo-Neto,LeonardoPolizello,Ana Cristina M.Lucisano-Valim,Yara M.Lopes,Norberto P.Lopes,João Luis C.eng2010-06-02T00:00:00Zoai:scielo:S0100-40422010000400019Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2010-06-02T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv In vitro study of antioxidant and scavenger properties of phenolic compounds from Lychnophora species
title In vitro study of antioxidant and scavenger properties of phenolic compounds from Lychnophora species
spellingShingle In vitro study of antioxidant and scavenger properties of phenolic compounds from Lychnophora species
Grael,Cristiane F. F.
antioxidant activity
Lychnophora
flavonoids
title_short In vitro study of antioxidant and scavenger properties of phenolic compounds from Lychnophora species
title_full In vitro study of antioxidant and scavenger properties of phenolic compounds from Lychnophora species
title_fullStr In vitro study of antioxidant and scavenger properties of phenolic compounds from Lychnophora species
title_full_unstemmed In vitro study of antioxidant and scavenger properties of phenolic compounds from Lychnophora species
title_sort In vitro study of antioxidant and scavenger properties of phenolic compounds from Lychnophora species
author Grael,Cristiane F. F.
author_facet Grael,Cristiane F. F.
Kanashiro,Alexandre
Kabeya,Luciana M.
Jordão,Christiane O.
Takeara,Renata
Gobbo-Neto,Leonardo
Polizello,Ana Cristina M.
Lucisano-Valim,Yara M.
Lopes,Norberto P.
Lopes,João Luis C.
author_role author
author2 Kanashiro,Alexandre
Kabeya,Luciana M.
Jordão,Christiane O.
Takeara,Renata
Gobbo-Neto,Leonardo
Polizello,Ana Cristina M.
Lucisano-Valim,Yara M.
Lopes,Norberto P.
Lopes,João Luis C.
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Grael,Cristiane F. F.
Kanashiro,Alexandre
Kabeya,Luciana M.
Jordão,Christiane O.
Takeara,Renata
Gobbo-Neto,Leonardo
Polizello,Ana Cristina M.
Lucisano-Valim,Yara M.
Lopes,Norberto P.
Lopes,João Luis C.
dc.subject.por.fl_str_mv antioxidant activity
Lychnophora
flavonoids
topic antioxidant activity
Lychnophora
flavonoids
description This paper describes the antioxidant effects of thirteen phenolic compounds isolated from plants of the genus Lychnophora. Two assays were performed to evaluate these effects: a cellular test that measured the luminol-enhanced chemiluminescence produced by neutrophils stimulated with opsonized zymosan and a cell-free test involving horseradish peroxidase-H2O2-luminol. In both assays, the antioxidant activity of the phenolic compounds was dependent on their concentration and chemical structure. Our results suggest that the ability of phenolic compounds from Lychnophora species to scavenge and inhibit the generation of ROS may be a mechanism underlying the anti-inflammatory activity of extracts from Lychnophora spp.
publishDate 2010
dc.date.none.fl_str_mv 2010-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010000400019
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010000400019
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-40422010000400019
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.33 n.4 2010
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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