HIV - recentes avanços na pesquisa de fármacos
Autor(a) principal: | |
---|---|
Data de Publicação: | 2008 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Química Nova (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000800035 |
Resumo: | The development of new antiretroviral drugs is a dynamic process that is continuously fueled by identification of new molecular targets and new compounds for know targets. The current available drugs can be classified into five categories: nucleoside analogues reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, protease inhibitors, integrase inhibitors and entry inhibitors (fusion inhibitors and CCR5 antagonist). In addition, the maturation inhibitors may be considered as potential target for chemotherapeutic intervention. This review presents some anti-HIV agents that have already gone through the advance development process for final approval for the treatment of AIDS. |
id |
SBQ-3_eab0469c553296fb7a28f8de12bb5f0c |
---|---|
oai_identifier_str |
oai:scielo:S0100-40422008000800035 |
network_acronym_str |
SBQ-3 |
network_name_str |
Química Nova (Online) |
repository_id_str |
|
spelling |
HIV - recentes avanços na pesquisa de fármacosanti-HIV drugsAIDSnew drugsThe development of new antiretroviral drugs is a dynamic process that is continuously fueled by identification of new molecular targets and new compounds for know targets. The current available drugs can be classified into five categories: nucleoside analogues reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, protease inhibitors, integrase inhibitors and entry inhibitors (fusion inhibitors and CCR5 antagonist). In addition, the maturation inhibitors may be considered as potential target for chemotherapeutic intervention. This review presents some anti-HIV agents that have already gone through the advance development process for final approval for the treatment of AIDS.Sociedade Brasileira de Química2008-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000800035Química Nova v.31 n.8 2008reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422008000800035info:eu-repo/semantics/openAccessCunico,WilsonGomes,Claudia R. B.Vellasco Junior,Walcimar T.por2009-01-16T00:00:00Zoai:scielo:S0100-40422008000800035Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2009-01-16T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
HIV - recentes avanços na pesquisa de fármacos |
title |
HIV - recentes avanços na pesquisa de fármacos |
spellingShingle |
HIV - recentes avanços na pesquisa de fármacos Cunico,Wilson anti-HIV drugs AIDS new drugs |
title_short |
HIV - recentes avanços na pesquisa de fármacos |
title_full |
HIV - recentes avanços na pesquisa de fármacos |
title_fullStr |
HIV - recentes avanços na pesquisa de fármacos |
title_full_unstemmed |
HIV - recentes avanços na pesquisa de fármacos |
title_sort |
HIV - recentes avanços na pesquisa de fármacos |
author |
Cunico,Wilson |
author_facet |
Cunico,Wilson Gomes,Claudia R. B. Vellasco Junior,Walcimar T. |
author_role |
author |
author2 |
Gomes,Claudia R. B. Vellasco Junior,Walcimar T. |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Cunico,Wilson Gomes,Claudia R. B. Vellasco Junior,Walcimar T. |
dc.subject.por.fl_str_mv |
anti-HIV drugs AIDS new drugs |
topic |
anti-HIV drugs AIDS new drugs |
description |
The development of new antiretroviral drugs is a dynamic process that is continuously fueled by identification of new molecular targets and new compounds for know targets. The current available drugs can be classified into five categories: nucleoside analogues reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, protease inhibitors, integrase inhibitors and entry inhibitors (fusion inhibitors and CCR5 antagonist). In addition, the maturation inhibitors may be considered as potential target for chemotherapeutic intervention. This review presents some anti-HIV agents that have already gone through the advance development process for final approval for the treatment of AIDS. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000800035 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000800035 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
10.1590/S0100-40422008000800035 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Química Nova v.31 n.8 2008 reponame:Química Nova (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Química Nova (Online) |
collection |
Química Nova (Online) |
repository.name.fl_str_mv |
Química Nova (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
quimicanova@sbq.org.br |
_version_ |
1750318108374990848 |