Efeitos do treinamento físico combinado no desempenho cardiovascular e metabólico em indivíduos diabéticos – ensaio clínico randomizado e controlado

Detalhes bibliográficos
Autor(a) principal: Bassi, Daniela
Data de Publicação: 2016
Tipo de documento: Tese
Idioma: por
Título da fonte: Repositório Institucional da UFSCAR
Texto Completo: https://repositorio.ufscar.br/handle/ufscar/8088
Resumo: The thesis consists of three studies described below. Study I, entitled: Poor glycemic control impacts the linear dynamic and nonlinear heart rate in type 2 diabetes mellitus (T2DM) whose objective was to evaluate the relationship between glycemic control and cardiac autonomic modulation in patients with T2DM without autonomic neuropathy cardiovascular. This is a descriptive, prospective and cross-sectional study. The resting heart rate (HR) and RR interval (RR intervals) were obtained and calculated by linear methods and nonlinear heart rate variability (HRV). Insulin, HOMA-IR, fasting glucose and HbA1c were obtained by blood tests. We concluded that the poor glycemic control associated with cardiac autonomic modulation indices in patients with type 2 diabetes, though not exhibit cardiovascular autonomic neuropathy. Following the Study II, entitled Type 2 diabetes coexistence of effects and systemic hypertension (SH) in HRV and cardiorespiratory performance, which aimed to evaluate the influence of hypertension in cardiac autonomic neuropathy and cardiorespiratory fitness in subjects with diabetes mellitus type 2. The evaluation included collection of iRR for further analysis of HRV, it was collected in the supine position followed by incremental cardiopulmonary exercise test (ICET) on a cycle ergometer. The results revealed a greater loss of HRV when there is overlapping of diseases. Additionally, there was an association of responses affected HRV with cardiopulmonary function markers impaired to exercise. Finally, the Study III, entitled: Potential effects on cardiorespiratory and metabolic status after a physical aerobic concurrent training program and has resisted in diabetic volunteers - Randomized Study and controlled. The objective was to evaluate metabolic profile, glycemic control and exercise capacity in diabetic volunteers after participating in an aerobic and resistance concurrent training program (AR-CT) for a period of three months. The evaluation included the ICET the cycle ergometer and 1-RM tests. Ventilation, hemodynamic measurements were performed during the ICET and peripheral muscle strength by isokinetic dynamometer. The program consisted of 30 minutes of aerobic exercise and 30 minutes of resistance exercise of upper and lower limbs. The results showed an improvement in glycemic control and lipid profile in addition to increased peripheral muscle strength and exercise capacity. These data together suggest that the exercise program constitutes an important strategy in the treatment of type 2 diabetes, producing both physiological and functional improvements in this population.
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spelling Bassi, DanielaSilva, Audrey Borghihttp://lattes.cnpq.br/4855616925791895http://lattes.cnpq.br/0861598490954598f7ef1380-c0d2-4c29-9c0b-8809c007fedc2016-10-20T19:56:15Z2016-10-20T19:56:15Z2016-03-22BASSI, Daniela. Efeitos do treinamento físico combinado no desempenho cardiovascular e metabólico em indivíduos diabéticos – ensaio clínico randomizado e controlado. 2016. Tese (Doutorado em Fisioterapia) – Universidade Federal de São Carlos, São Carlos, 2016. Disponível em: https://repositorio.ufscar.br/handle/ufscar/8088.https://repositorio.ufscar.br/handle/ufscar/8088The thesis consists of three studies described below. Study I, entitled: Poor glycemic control impacts the linear dynamic and nonlinear heart rate in type 2 diabetes mellitus (T2DM) whose objective was to evaluate the relationship between glycemic control and cardiac autonomic modulation in patients with T2DM without autonomic neuropathy cardiovascular. This is a descriptive, prospective and cross-sectional study. The resting heart rate (HR) and RR interval (RR intervals) were obtained and calculated by linear methods and nonlinear heart rate variability (HRV). Insulin, HOMA-IR, fasting glucose and HbA1c were obtained by blood tests. We concluded that the poor glycemic control associated with cardiac autonomic modulation indices in patients with type 2 diabetes, though not exhibit cardiovascular autonomic neuropathy. Following the Study II, entitled Type 2 diabetes coexistence of effects and systemic hypertension (SH) in HRV and cardiorespiratory performance, which aimed to evaluate the influence of hypertension in cardiac autonomic neuropathy and cardiorespiratory fitness in subjects with diabetes mellitus type 2. The evaluation included collection of iRR for further analysis of HRV, it was collected in the supine position followed by incremental cardiopulmonary exercise test (ICET) on a cycle ergometer. The results revealed a greater loss of HRV when there is overlapping of diseases. Additionally, there was an association of responses affected HRV with cardiopulmonary function markers impaired to exercise. Finally, the Study III, entitled: Potential effects on cardiorespiratory and metabolic status after a physical aerobic concurrent training program and has resisted in diabetic volunteers - Randomized Study and controlled. The objective was to evaluate metabolic profile, glycemic control and exercise capacity in diabetic volunteers after participating in an aerobic and resistance concurrent training program (AR-CT) for a period of three months. The evaluation included the ICET the cycle ergometer and 1-RM tests. Ventilation, hemodynamic measurements were performed during the ICET and peripheral muscle strength by isokinetic dynamometer. The program consisted of 30 minutes of aerobic exercise and 30 minutes of resistance exercise of upper and lower limbs. The results showed an improvement in glycemic control and lipid profile in addition to increased peripheral muscle strength and exercise capacity. These data together suggest that the exercise program constitutes an important strategy in the treatment of type 2 diabetes, producing both physiological and functional improvements in this population.A tese constou de três estudos descritos a seguir. O Estudo I, intitulado: Pobre controle glicêmico impacta a dinâmica linear e não-linear da frequência cardíaca no diabetes mellitus tipo 2 (DM2), cujo objetivo foi avaliar a relação entre controle glicêmico e modulação autonômica cardíaca em indivíduos com DM2 sem neuropatia autonômica cardiovascular. Trata-se de um estudo descritivo, prospectivo e transversal. A frequência cardíaca de repouso (FC) e intervalo RR (iRR) foram obtidos e calculados por métodos lineares e não-lineares de variabilidade de frequência cardíaca (VFC). Insulina, HOMA-IR, glicemia de jejum e HbA1c foram obtidas por análises sanguíneas. Concluímos que o controle glicêmico deficiente relaciona-se com índices de modulação autonômica cardíaca em indivíduos com DM2, ainda que não apresentem neuropatia autonômica cardiovascular. Na sequência, o Estudo II, intitulado: Efeitos da coexistência da diabetes tipo 2 e da hipertensão arterial sistêmica (HAS) na VFC e no desempenho cardiorrespiratório, que objetivou avaliar a influência da HAS na modulação autonômica cardíaca e aptidão cardiorrespiratória de sujeitos com diabetes mellitus tipo 2. A avaliação incluiu coleta de dos iRR, para posterior análise da VFC, a mesma foi coletada na posição supina seguida de teste de exercício cardiopulmonar incremental (TECI) no cicloergômetro. Os resultados revelaram um maior prejuízo da VFC quando há sobreposição das doenças. Adicionalmente, houve associação das respostas prejudicadas da VFC com marcadores de função cardiopulmonar prejudicada ao exercício. Finalmente, o Estudo III, intitulado: Potenciais efeitos no status cardiorrespiratório e metabólico após um programa de treinamento físico concorrente aeróbio e resistido em diabéticos – Estudo Randomizado e Controlado. O objetivo foi avaliar perfil metabólico, controle glicêmico e capacidade de exercício em voluntários diabéticos após participarem de um programa de treinamento concorrente aeróbio e resistido (TC-AR) por um período de 3 meses. A avaliação incluiu o TECI no cicloergômetro, exames laboratoriais, teste isocinético e teste de 1-RM. Foram realizadas medidas ventilatórias, hemodinâmicas durante o TECI bem como da força muscular periférica por meio da dinamometria isocinética. O programa foi constituído por 30 minutos de exercícios aeróbios e 30 minutos de exercícios resistidos de membros superiores e inferiores. Os resultados mostraram melhora do controle glicêmico e do perfil lipídico, além de aumento da força muscular periférica e da capacidade de exercício. Esses dados juntos sugerem que o programa de exercícios constitui-se uma importante estratégia no tratamento de DM2, produzindo melhoras tanto fisiológicas como funcionais nessa população.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)porUniversidade Federal de São CarlosCâmpus São CarlosPrograma de Pós-Graduação em Fisioterapia - PPGFtUFSCarDiabetes mellitus tipo 2HipertensãoTreino concorrenteControle glicêmicoVariabilidade da frequência cardíacaType 2 diabetes mellitusHypertensionConcurrent trainingGlycemic controlHeart rate variabilityCIENCIAS DA SAUDE::FISIOTERAPIA E TERAPIA OCUPACIONALEfeitos do treinamento físico combinado no desempenho cardiovascular e metabólico em indivíduos diabéticos – ensaio clínico randomizado e controladoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisOnline600600223468fb-3ac6-44de-8f8a-d0ff9e395bd0info:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFSCARinstname:Universidade Federal de São Carlos (UFSCAR)instacron:UFSCARORIGINALTeseDB.pdfTeseDB.pdfapplication/pdf11488073https://repositorio.ufscar.br/bitstream/ufscar/8088/1/TeseDB.pdfe161623d5cf03f13400ba78b788a3243MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81957https://repositorio.ufscar.br/bitstream/ufscar/8088/2/license.txtae0398b6f8b235e40ad82cba6c50031dMD52TEXTTeseDB.pdf.txtTeseDB.pdf.txtExtracted texttext/plain211975https://repositorio.ufscar.br/bitstream/ufscar/8088/3/TeseDB.pdf.txt149faed0ebb0e0fd6bdc1b7a55959bf1MD53THUMBNAILTeseDB.pdf.jpgTeseDB.pdf.jpgIM Thumbnailimage/jpeg14677https://repositorio.ufscar.br/bitstream/ufscar/8088/4/TeseDB.pdf.jpg2a08f8670999f0dea2c6692f87c712bdMD54ufscar/80882023-09-18 18:31:00.061oai:repositorio.ufscar.br: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Repositório InstitucionalPUBhttps://repositorio.ufscar.br/oai/requestopendoar:43222023-09-18T18:31Repositório Institucional da UFSCAR - Universidade Federal de São Carlos (UFSCAR)false
dc.title.por.fl_str_mv Efeitos do treinamento físico combinado no desempenho cardiovascular e metabólico em indivíduos diabéticos – ensaio clínico randomizado e controlado
title Efeitos do treinamento físico combinado no desempenho cardiovascular e metabólico em indivíduos diabéticos – ensaio clínico randomizado e controlado
spellingShingle Efeitos do treinamento físico combinado no desempenho cardiovascular e metabólico em indivíduos diabéticos – ensaio clínico randomizado e controlado
Bassi, Daniela
Diabetes mellitus tipo 2
Hipertensão
Treino concorrente
Controle glicêmico
Variabilidade da frequência cardíaca
Type 2 diabetes mellitus
Hypertension
Concurrent training
Glycemic control
Heart rate variability
CIENCIAS DA SAUDE::FISIOTERAPIA E TERAPIA OCUPACIONAL
title_short Efeitos do treinamento físico combinado no desempenho cardiovascular e metabólico em indivíduos diabéticos – ensaio clínico randomizado e controlado
title_full Efeitos do treinamento físico combinado no desempenho cardiovascular e metabólico em indivíduos diabéticos – ensaio clínico randomizado e controlado
title_fullStr Efeitos do treinamento físico combinado no desempenho cardiovascular e metabólico em indivíduos diabéticos – ensaio clínico randomizado e controlado
title_full_unstemmed Efeitos do treinamento físico combinado no desempenho cardiovascular e metabólico em indivíduos diabéticos – ensaio clínico randomizado e controlado
title_sort Efeitos do treinamento físico combinado no desempenho cardiovascular e metabólico em indivíduos diabéticos – ensaio clínico randomizado e controlado
author Bassi, Daniela
author_facet Bassi, Daniela
author_role author
dc.contributor.authorlattes.por.fl_str_mv http://lattes.cnpq.br/0861598490954598
dc.contributor.author.fl_str_mv Bassi, Daniela
dc.contributor.advisor1.fl_str_mv Silva, Audrey Borghi
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/4855616925791895
dc.contributor.authorID.fl_str_mv f7ef1380-c0d2-4c29-9c0b-8809c007fedc
contributor_str_mv Silva, Audrey Borghi
dc.subject.por.fl_str_mv Diabetes mellitus tipo 2
Hipertensão
Treino concorrente
Controle glicêmico
Variabilidade da frequência cardíaca
topic Diabetes mellitus tipo 2
Hipertensão
Treino concorrente
Controle glicêmico
Variabilidade da frequência cardíaca
Type 2 diabetes mellitus
Hypertension
Concurrent training
Glycemic control
Heart rate variability
CIENCIAS DA SAUDE::FISIOTERAPIA E TERAPIA OCUPACIONAL
dc.subject.eng.fl_str_mv Type 2 diabetes mellitus
Hypertension
Concurrent training
Glycemic control
Heart rate variability
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE::FISIOTERAPIA E TERAPIA OCUPACIONAL
description The thesis consists of three studies described below. Study I, entitled: Poor glycemic control impacts the linear dynamic and nonlinear heart rate in type 2 diabetes mellitus (T2DM) whose objective was to evaluate the relationship between glycemic control and cardiac autonomic modulation in patients with T2DM without autonomic neuropathy cardiovascular. This is a descriptive, prospective and cross-sectional study. The resting heart rate (HR) and RR interval (RR intervals) were obtained and calculated by linear methods and nonlinear heart rate variability (HRV). Insulin, HOMA-IR, fasting glucose and HbA1c were obtained by blood tests. We concluded that the poor glycemic control associated with cardiac autonomic modulation indices in patients with type 2 diabetes, though not exhibit cardiovascular autonomic neuropathy. Following the Study II, entitled Type 2 diabetes coexistence of effects and systemic hypertension (SH) in HRV and cardiorespiratory performance, which aimed to evaluate the influence of hypertension in cardiac autonomic neuropathy and cardiorespiratory fitness in subjects with diabetes mellitus type 2. The evaluation included collection of iRR for further analysis of HRV, it was collected in the supine position followed by incremental cardiopulmonary exercise test (ICET) on a cycle ergometer. The results revealed a greater loss of HRV when there is overlapping of diseases. Additionally, there was an association of responses affected HRV with cardiopulmonary function markers impaired to exercise. Finally, the Study III, entitled: Potential effects on cardiorespiratory and metabolic status after a physical aerobic concurrent training program and has resisted in diabetic volunteers - Randomized Study and controlled. The objective was to evaluate metabolic profile, glycemic control and exercise capacity in diabetic volunteers after participating in an aerobic and resistance concurrent training program (AR-CT) for a period of three months. The evaluation included the ICET the cycle ergometer and 1-RM tests. Ventilation, hemodynamic measurements were performed during the ICET and peripheral muscle strength by isokinetic dynamometer. The program consisted of 30 minutes of aerobic exercise and 30 minutes of resistance exercise of upper and lower limbs. The results showed an improvement in glycemic control and lipid profile in addition to increased peripheral muscle strength and exercise capacity. These data together suggest that the exercise program constitutes an important strategy in the treatment of type 2 diabetes, producing both physiological and functional improvements in this population.
publishDate 2016
dc.date.accessioned.fl_str_mv 2016-10-20T19:56:15Z
dc.date.available.fl_str_mv 2016-10-20T19:56:15Z
dc.date.issued.fl_str_mv 2016-03-22
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dc.identifier.citation.fl_str_mv BASSI, Daniela. Efeitos do treinamento físico combinado no desempenho cardiovascular e metabólico em indivíduos diabéticos – ensaio clínico randomizado e controlado. 2016. Tese (Doutorado em Fisioterapia) – Universidade Federal de São Carlos, São Carlos, 2016. Disponível em: https://repositorio.ufscar.br/handle/ufscar/8088.
dc.identifier.uri.fl_str_mv https://repositorio.ufscar.br/handle/ufscar/8088
identifier_str_mv BASSI, Daniela. Efeitos do treinamento físico combinado no desempenho cardiovascular e metabólico em indivíduos diabéticos – ensaio clínico randomizado e controlado. 2016. Tese (Doutorado em Fisioterapia) – Universidade Federal de São Carlos, São Carlos, 2016. Disponível em: https://repositorio.ufscar.br/handle/ufscar/8088.
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dc.publisher.none.fl_str_mv Universidade Federal de São Carlos
Câmpus São Carlos
dc.publisher.program.fl_str_mv Programa de Pós-Graduação em Fisioterapia - PPGFt
dc.publisher.initials.fl_str_mv UFSCar
publisher.none.fl_str_mv Universidade Federal de São Carlos
Câmpus São Carlos
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