Relação entre queixa de memória, alterações cognitivas, autopercepção da saúde e ADAM10, em idosos

Detalhes bibliográficos
Autor(a) principal: Almeida, Mariana Luciano de
Data de Publicação: 2016
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFSCAR
Texto Completo: https://repositorio.ufscar.br/handle/ufscar/8718
Resumo: There is a wide divergence of results in the literature on the clinical relevance and the etiology of memory complaints (MC). Currently QM is being studied as pre-clinical symptom of Alzheimer's disease before a possible CCL setting. Our hypothesis is that MC may be associated with lower performance on cognitive tests or a low self-rated health. Objective. To investigate the relationship among MC in elderly patients with objective cognitive impairment and self-rated health. Method. This was a cross-sectional, correlational and quantitative study. The instruments used were the Memory Complaint Scale (MCS) - forms A and B, Addenbrooke’s Cognitive Examination – Revised (CEA-R), Mini-Mental State Examination (MMSE), Clock Drawing Test (CDT), Medical Outcomes Study 8-item Short-Form Heath Survey, Geriatric Depression Scale and a sociodemographic questionnaire. Results. Participated in this study 83 subjects, divided between the two forms of MCS evaluation scale. Sociodemographic groups were very similar, with no significant differences with MC. According to MCS-A, there was a significant association only with the CDT. MCS-B was associated with ACE-R and its domains memory, fluency and visual spatial orientation?. A ROC curve was drawn from the results of MCS-B in relation to the ACE-R and MMSE, demonstrating the high specificity of the instrument. Conclusion. In this study it was not found robust results with MC reported by the elderly and changes in cognitive screening tests. However, when the informant reported the complaint, the analysis with cognitive performance levels were more consolidated. This results highligh the need to include and empower perception of someone who knows enough the elderly to assess the MC globally.
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spelling Almeida, Mariana Luciano deVale, Francisco de Assis Carvalho dohttp://lattes.cnpq.br/7135183635933470Cominetti, Márcia Reginahttp://lattes.cnpq.br/3725318894555272http://lattes.cnpq.br/1590881498202887a06c4230-1e3a-42ad-a6b1-87f292313a942017-05-04T13:23:35Z2017-05-04T13:23:35Z2016-02-15ALMEIDA, Mariana Luciano de. Relação entre queixa de memória, alterações cognitivas, autopercepção da saúde e ADAM10, em idosos. 2016. Dissertação (Mestrado em Enfermagem) – Universidade Federal de São Carlos, São Carlos, 2016. Disponível em: https://repositorio.ufscar.br/handle/ufscar/8718.https://repositorio.ufscar.br/handle/ufscar/8718There is a wide divergence of results in the literature on the clinical relevance and the etiology of memory complaints (MC). Currently QM is being studied as pre-clinical symptom of Alzheimer's disease before a possible CCL setting. Our hypothesis is that MC may be associated with lower performance on cognitive tests or a low self-rated health. Objective. To investigate the relationship among MC in elderly patients with objective cognitive impairment and self-rated health. Method. This was a cross-sectional, correlational and quantitative study. The instruments used were the Memory Complaint Scale (MCS) - forms A and B, Addenbrooke’s Cognitive Examination – Revised (CEA-R), Mini-Mental State Examination (MMSE), Clock Drawing Test (CDT), Medical Outcomes Study 8-item Short-Form Heath Survey, Geriatric Depression Scale and a sociodemographic questionnaire. Results. Participated in this study 83 subjects, divided between the two forms of MCS evaluation scale. Sociodemographic groups were very similar, with no significant differences with MC. According to MCS-A, there was a significant association only with the CDT. MCS-B was associated with ACE-R and its domains memory, fluency and visual spatial orientation?. A ROC curve was drawn from the results of MCS-B in relation to the ACE-R and MMSE, demonstrating the high specificity of the instrument. Conclusion. In this study it was not found robust results with MC reported by the elderly and changes in cognitive screening tests. However, when the informant reported the complaint, the analysis with cognitive performance levels were more consolidated. This results highligh the need to include and empower perception of someone who knows enough the elderly to assess the MC globally.Introdução. Existe uma grande divergência de resultados na literatura quanto à relevância clínica e à etiologia da queixa de memória (QM). Atualmente a QM vem sendo estudada como sintoma pré-clínico da doença de Alzheimer, antes de se instalar um possível quadro de CCL. A hipótese deste estudo é que a QM pode estar associada a um desempenho inferior nos testes cognitivos ou a uma baixa autopercepção de saúde. Objetivo. Investigar a relação da QM em idosos com alterações cognitivas objetivas e autopercepção da saúde. Método. Tratou-se de um estudo transversal, correlacional e de caráter quantitativo. Os instrumentos aplicados foram a Escala de Queixa de Memória – formas A e B, Exame Cognitivo de Addenbrooke – Revisado, Mini-Exame do Estado Mental, Teste do Desenho do Relógio, Medical Outcomes Study 8-item Short-Form Heath Survey, Escala de Depressão Geriátrica e um questionário sociodemográfico. Resultados. Participaram da pesquisa 83 sujeitos, divididos entre as formas de avaliação da EQM para as análises. Com relação às variáveis sociodemográficas os grupos foram muito semelhantes, não havendo diferenças significativas com a QM. De acordo com a EQM-A, houve associação significativa apenas com o TDR. A EQM-B apresentou associação com a ACE-R total e os domínios memória, fluência e visual espacial. Foi elaborada uma curva ROC a partir dos resultados da EQM-B em relação à ACE-R e ao MEEM, demonstrando alta especificidade do instrumento. Conclusão. Neste estudo não foram encontrados resultados tão robustos com a QM relatada pelo idoso e alterações nos testes de rastreio cognitivo. Contudo, quando o informante relatou a queixa, as análises com os níveis de desempenho cognitivo mostraram-se mais consolidadas, evidenciando a necessidade da inclusão e valorização da percepção de alguém que conheça suficientemente o idoso para avaliar a QM de forma global.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)porUniversidade Federal de São CarlosCâmpus São CarlosPrograma de Pós-Graduação em Enfermagem - PPGEnfUFSCarQueixa de memóriaAlteração cognitivaAutopercepção de saúdeIdososMemory complaintCognitive impairmentSelf-perceived healthElderlyCIENCIAS DA SAUDE::ENFERMAGEMRelação entre queixa de memória, alterações cognitivas, autopercepção da saúde e ADAM10, em idososinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisOnline600600835bc697-e987-4085-a10f-63fc1af3bdd9info:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFSCARinstname:Universidade Federal de São Carlos (UFSCAR)instacron:UFSCARORIGINALDissMLA.pdfDissMLA.pdfapplication/pdf1498492https://repositorio.ufscar.br/bitstream/ufscar/8718/1/DissMLA.pdfa86fb09f8bdcd3334a09629eea1dc03dMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81957https://repositorio.ufscar.br/bitstream/ufscar/8718/2/license.txtae0398b6f8b235e40ad82cba6c50031dMD52TEXTDissMLA.pdf.txtDissMLA.pdf.txtExtracted texttext/plain130774https://repositorio.ufscar.br/bitstream/ufscar/8718/3/DissMLA.pdf.txtf1e609026917ce6cd9cdd8214c18f9a3MD53THUMBNAILDissMLA.pdf.jpgDissMLA.pdf.jpgIM Thumbnailimage/jpeg6185https://repositorio.ufscar.br/bitstream/ufscar/8718/4/DissMLA.pdf.jpgf4d7f08ff66177e874f33e2bd94e08ceMD54ufscar/87182023-09-18 18:31:25.197oai:repositorio.ufscar.br:ufscar/8718TElDRU7Dh0EgREUgRElTVFJJQlVJw4fDg08gTsODTy1FWENMVVNJVkEKCkNvbSBhIGFwcmVzZW50YcOnw6NvIGRlc3RhIGxpY2Vuw6dhLCB2b2PDqiAobyBhdXRvciAoZXMpIG91IG8gdGl0dWxhciBkb3MgZGlyZWl0b3MgZGUgYXV0b3IpIGNvbmNlZGUgw6AgVW5pdmVyc2lkYWRlCkZlZGVyYWwgZGUgU8OjbyBDYXJsb3MgbyBkaXJlaXRvIG7Do28tZXhjbHVzaXZvIGRlIHJlcHJvZHV6aXIsICB0cmFkdXppciAoY29uZm9ybWUgZGVmaW5pZG8gYWJhaXhvKSwgZS9vdQpkaXN0cmlidWlyIGEgc3VhIHRlc2Ugb3UgZGlzc2VydGHDp8OjbyAoaW5jbHVpbmRvIG8gcmVzdW1vKSBwb3IgdG9kbyBvIG11bmRvIG5vIGZvcm1hdG8gaW1wcmVzc28gZSBlbGV0csO0bmljbyBlCmVtIHF1YWxxdWVyIG1laW8sIGluY2x1aW5kbyBvcyBmb3JtYXRvcyDDoXVkaW8gb3UgdsOtZGVvLgoKVm9jw6ogY29uY29yZGEgcXVlIGEgVUZTQ2FyIHBvZGUsIHNlbSBhbHRlcmFyIG8gY29udGXDumRvLCB0cmFuc3BvciBhIHN1YSB0ZXNlIG91IGRpc3NlcnRhw6fDo28KcGFyYSBxdWFscXVlciBtZWlvIG91IGZvcm1hdG8gcGFyYSBmaW5zIGRlIHByZXNlcnZhw6fDo28uCgpWb2PDqiB0YW1iw6ltIGNvbmNvcmRhIHF1ZSBhIFVGU0NhciBwb2RlIG1hbnRlciBtYWlzIGRlIHVtYSBjw7NwaWEgYSBzdWEgdGVzZSBvdQpkaXNzZXJ0YcOnw6NvIHBhcmEgZmlucyBkZSBzZWd1cmFuw6dhLCBiYWNrLXVwIGUgcHJlc2VydmHDp8Ojby4KClZvY8OqIGRlY2xhcmEgcXVlIGEgc3VhIHRlc2Ugb3UgZGlzc2VydGHDp8OjbyDDqSBvcmlnaW5hbCBlIHF1ZSB2b2PDqiB0ZW0gbyBwb2RlciBkZSBjb25jZWRlciBvcyBkaXJlaXRvcyBjb250aWRvcwpuZXN0YSBsaWNlbsOnYS4gVm9jw6ogdGFtYsOpbSBkZWNsYXJhIHF1ZSBvIGRlcMOzc2l0byBkYSBzdWEgdGVzZSBvdSBkaXNzZXJ0YcOnw6NvIG7Do28sIHF1ZSBzZWphIGRlIHNldQpjb25oZWNpbWVudG8sIGluZnJpbmdlIGRpcmVpdG9zIGF1dG9yYWlzIGRlIG5pbmd1w6ltLgoKQ2FzbyBhIHN1YSB0ZXNlIG91IGRpc3NlcnRhw6fDo28gY29udGVuaGEgbWF0ZXJpYWwgcXVlIHZvY8OqIG7Do28gcG9zc3VpIGEgdGl0dWxhcmlkYWRlIGRvcyBkaXJlaXRvcyBhdXRvcmFpcywgdm9jw6oKZGVjbGFyYSBxdWUgb2J0ZXZlIGEgcGVybWlzc8OjbyBpcnJlc3RyaXRhIGRvIGRldGVudG9yIGRvcyBkaXJlaXRvcyBhdXRvcmFpcyBwYXJhIGNvbmNlZGVyIMOgIFVGU0NhcgpvcyBkaXJlaXRvcyBhcHJlc2VudGFkb3MgbmVzdGEgbGljZW7Dp2EsIGUgcXVlIGVzc2UgbWF0ZXJpYWwgZGUgcHJvcHJpZWRhZGUgZGUgdGVyY2Vpcm9zIGVzdMOhIGNsYXJhbWVudGUKaWRlbnRpZmljYWRvIGUgcmVjb25oZWNpZG8gbm8gdGV4dG8gb3Ugbm8gY29udGXDumRvIGRhIHRlc2Ugb3UgZGlzc2VydGHDp8OjbyBvcmEgZGVwb3NpdGFkYS4KCkNBU08gQSBURVNFIE9VIERJU1NFUlRBw4fDg08gT1JBIERFUE9TSVRBREEgVEVOSEEgU0lETyBSRVNVTFRBRE8gREUgVU0gUEFUUk9Dw41OSU8gT1UKQVBPSU8gREUgVU1BIEFHw4pOQ0lBIERFIEZPTUVOVE8gT1UgT1VUUk8gT1JHQU5JU01PIFFVRSBOw4NPIFNFSkEgQSBVRlNDYXIsClZPQ8OKIERFQ0xBUkEgUVVFIFJFU1BFSVRPVSBUT0RPUyBFIFFVQUlTUVVFUiBESVJFSVRPUyBERSBSRVZJU8ODTyBDT01PClRBTULDiU0gQVMgREVNQUlTIE9CUklHQcOHw5VFUyBFWElHSURBUyBQT1IgQ09OVFJBVE8gT1UgQUNPUkRPLgoKQSBVRlNDYXIgc2UgY29tcHJvbWV0ZSBhIGlkZW50aWZpY2FyIGNsYXJhbWVudGUgbyBzZXUgbm9tZSAocykgb3UgbyhzKSBub21lKHMpIGRvKHMpCmRldGVudG9yKGVzKSBkb3MgZGlyZWl0b3MgYXV0b3JhaXMgZGEgdGVzZSBvdSBkaXNzZXJ0YcOnw6NvLCBlIG7Do28gZmFyw6EgcXVhbHF1ZXIgYWx0ZXJhw6fDo28sIGFsw6ltIGRhcXVlbGFzCmNvbmNlZGlkYXMgcG9yIGVzdGEgbGljZW7Dp2EuCg==Repositório InstitucionalPUBhttps://repositorio.ufscar.br/oai/requestopendoar:43222023-09-18T18:31:25Repositório Institucional da UFSCAR - Universidade Federal de São Carlos (UFSCAR)false
dc.title.por.fl_str_mv Relação entre queixa de memória, alterações cognitivas, autopercepção da saúde e ADAM10, em idosos
title Relação entre queixa de memória, alterações cognitivas, autopercepção da saúde e ADAM10, em idosos
spellingShingle Relação entre queixa de memória, alterações cognitivas, autopercepção da saúde e ADAM10, em idosos
Almeida, Mariana Luciano de
Queixa de memória
Alteração cognitiva
Autopercepção de saúde
Idosos
Memory complaint
Cognitive impairment
Self-perceived health
Elderly
CIENCIAS DA SAUDE::ENFERMAGEM
title_short Relação entre queixa de memória, alterações cognitivas, autopercepção da saúde e ADAM10, em idosos
title_full Relação entre queixa de memória, alterações cognitivas, autopercepção da saúde e ADAM10, em idosos
title_fullStr Relação entre queixa de memória, alterações cognitivas, autopercepção da saúde e ADAM10, em idosos
title_full_unstemmed Relação entre queixa de memória, alterações cognitivas, autopercepção da saúde e ADAM10, em idosos
title_sort Relação entre queixa de memória, alterações cognitivas, autopercepção da saúde e ADAM10, em idosos
author Almeida, Mariana Luciano de
author_facet Almeida, Mariana Luciano de
author_role author
dc.contributor.authorlattes.por.fl_str_mv http://lattes.cnpq.br/1590881498202887
dc.contributor.author.fl_str_mv Almeida, Mariana Luciano de
dc.contributor.advisor1.fl_str_mv Vale, Francisco de Assis Carvalho do
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/7135183635933470
dc.contributor.advisor-co1.fl_str_mv Cominetti, Márcia Regina
dc.contributor.advisor-co1Lattes.fl_str_mv http://lattes.cnpq.br/3725318894555272
dc.contributor.authorID.fl_str_mv a06c4230-1e3a-42ad-a6b1-87f292313a94
contributor_str_mv Vale, Francisco de Assis Carvalho do
Cominetti, Márcia Regina
dc.subject.por.fl_str_mv Queixa de memória
Alteração cognitiva
Autopercepção de saúde
Idosos
topic Queixa de memória
Alteração cognitiva
Autopercepção de saúde
Idosos
Memory complaint
Cognitive impairment
Self-perceived health
Elderly
CIENCIAS DA SAUDE::ENFERMAGEM
dc.subject.eng.fl_str_mv Memory complaint
Cognitive impairment
Self-perceived health
Elderly
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE::ENFERMAGEM
description There is a wide divergence of results in the literature on the clinical relevance and the etiology of memory complaints (MC). Currently QM is being studied as pre-clinical symptom of Alzheimer's disease before a possible CCL setting. Our hypothesis is that MC may be associated with lower performance on cognitive tests or a low self-rated health. Objective. To investigate the relationship among MC in elderly patients with objective cognitive impairment and self-rated health. Method. This was a cross-sectional, correlational and quantitative study. The instruments used were the Memory Complaint Scale (MCS) - forms A and B, Addenbrooke’s Cognitive Examination – Revised (CEA-R), Mini-Mental State Examination (MMSE), Clock Drawing Test (CDT), Medical Outcomes Study 8-item Short-Form Heath Survey, Geriatric Depression Scale and a sociodemographic questionnaire. Results. Participated in this study 83 subjects, divided between the two forms of MCS evaluation scale. Sociodemographic groups were very similar, with no significant differences with MC. According to MCS-A, there was a significant association only with the CDT. MCS-B was associated with ACE-R and its domains memory, fluency and visual spatial orientation?. A ROC curve was drawn from the results of MCS-B in relation to the ACE-R and MMSE, demonstrating the high specificity of the instrument. Conclusion. In this study it was not found robust results with MC reported by the elderly and changes in cognitive screening tests. However, when the informant reported the complaint, the analysis with cognitive performance levels were more consolidated. This results highligh the need to include and empower perception of someone who knows enough the elderly to assess the MC globally.
publishDate 2016
dc.date.issued.fl_str_mv 2016-02-15
dc.date.accessioned.fl_str_mv 2017-05-04T13:23:35Z
dc.date.available.fl_str_mv 2017-05-04T13:23:35Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
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status_str publishedVersion
dc.identifier.citation.fl_str_mv ALMEIDA, Mariana Luciano de. Relação entre queixa de memória, alterações cognitivas, autopercepção da saúde e ADAM10, em idosos. 2016. Dissertação (Mestrado em Enfermagem) – Universidade Federal de São Carlos, São Carlos, 2016. Disponível em: https://repositorio.ufscar.br/handle/ufscar/8718.
dc.identifier.uri.fl_str_mv https://repositorio.ufscar.br/handle/ufscar/8718
identifier_str_mv ALMEIDA, Mariana Luciano de. Relação entre queixa de memória, alterações cognitivas, autopercepção da saúde e ADAM10, em idosos. 2016. Dissertação (Mestrado em Enfermagem) – Universidade Federal de São Carlos, São Carlos, 2016. Disponível em: https://repositorio.ufscar.br/handle/ufscar/8718.
url https://repositorio.ufscar.br/handle/ufscar/8718
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dc.publisher.none.fl_str_mv Universidade Federal de São Carlos
Câmpus São Carlos
dc.publisher.program.fl_str_mv Programa de Pós-Graduação em Enfermagem - PPGEnf
dc.publisher.initials.fl_str_mv UFSCar
publisher.none.fl_str_mv Universidade Federal de São Carlos
Câmpus São Carlos
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reponame_str Repositório Institucional da UFSCAR
collection Repositório Institucional da UFSCAR
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