THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE

Detalhes bibliográficos
Autor(a) principal: Paz-Ibarra, Jose
Data de Publicação: 2020
Tipo de documento: preprint
Idioma: spa
Título da fonte: SciELO Preprints
Texto Completo: https://preprints.scielo.org/index.php/scielo/preprint/view/981
Resumo: Coronavirus disease compromises all biological organs and systems, either by direct commitment to specific tissues or by indirect effects. The endocrine system is no exception, and parenchyma and thyroid function have been reported to be impaired. In 2003 a histopathological study on the effects of SARS-CoV infection on the thyroid showed extensive damage to parafollicular cells and destruction and exfoliation of epithelial cells in the thyroid follicle, an interesting finding was the absence of an inflammatory infiltrate. which supported the hypothesis of extensive apoptosis responsible for the findings. In China, minimally invasive autopsies of different organs of patients who died of SARS-CoV-2 did not report abnormalities in thyroid follicular morphology, but noted lymphocytic infiltration in the interstitium; none of the tissue immunohistochemistry and PCR analyzes detected SARS-CoV-2 in the thyroid. The first case of thyroid alteration compatible with subacute thyroiditis in a patient with COVID-19 in Peru is presented.
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spelling THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASEGLANDULA TIROIDES, ¿OTRA VICTIMA DEL COVID-19? A PROPOSITO DE UN CASOCOVID-19SARS-CoV-2coronavirussubacute thyroiditisPeruCOVID-19SARS-CoV-2coronavirustiroiditis subagudaPerúCoronavirus disease compromises all biological organs and systems, either by direct commitment to specific tissues or by indirect effects. The endocrine system is no exception, and parenchyma and thyroid function have been reported to be impaired. In 2003 a histopathological study on the effects of SARS-CoV infection on the thyroid showed extensive damage to parafollicular cells and destruction and exfoliation of epithelial cells in the thyroid follicle, an interesting finding was the absence of an inflammatory infiltrate. which supported the hypothesis of extensive apoptosis responsible for the findings. In China, minimally invasive autopsies of different organs of patients who died of SARS-CoV-2 did not report abnormalities in thyroid follicular morphology, but noted lymphocytic infiltration in the interstitium; none of the tissue immunohistochemistry and PCR analyzes detected SARS-CoV-2 in the thyroid. The first case of thyroid alteration compatible with subacute thyroiditis in a patient with COVID-19 in Peru is presented.La enfermedad por coronavirus compromete todos los órganos y sistemas biológicos, ya sea por compromiso directo a tejidos específicos o por efectos indirectos. El sistema endocrino no es una excepción y la función y parénquima tiroideos se han reportado alterados. En el 2003 un estudio histopatológico sobre los efectos de la infección por SARS-CoV en la tiroides mostró una lesión extensa de las células para-foliculares y la destrucción y exfoliación de las células epiteliales en el folículo tiroideo, un hallazgo interesante fue la ausencia de infiltrado inflamatorio lo que respaldó la hipótesis de una apoptosis extensa responsable de los hallazgos. En China, autopsias mínimamente invasivas de diferentes órganos de pacientes fallecidos por SARS-CoV-2 no informaron anormalidades en la morfología folicular tiroidea, pero notaron infiltración linfocítica en el intersticio; ninguno de los análisis de inmuno-histoquímica tisular y PCR detectó SARS-CoV-2 en la tiroides. Se presenta el primer caso de alteración tiroidea compatible con tiroiditis subaguda en una paciente con COVID-19 en Perú.SciELO PreprintsSciELO PreprintsSciELO Preprints2020-07-20info:eu-repo/semantics/preprintinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://preprints.scielo.org/index.php/scielo/preprint/view/98110.1590/SciELOPreprints.981spahttps://preprints.scielo.org/index.php/scielo/article/view/981/1391Copyright (c) 2020 Jose Paz-Ibarrahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPaz-Ibarra, Josereponame:SciELO Preprintsinstname:SciELOinstacron:SCI2020-07-17T15:02:42Zoai:ops.preprints.scielo.org:preprint/981Servidor de preprintshttps://preprints.scielo.org/index.php/scieloONGhttps://preprints.scielo.org/index.php/scielo/oaiscielo.submission@scielo.orgopendoar:2020-07-17T15:02:42SciELO Preprints - SciELOfalse
dc.title.none.fl_str_mv THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE
GLANDULA TIROIDES, ¿OTRA VICTIMA DEL COVID-19? A PROPOSITO DE UN CASO
title THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE
spellingShingle THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE
Paz-Ibarra, Jose
COVID-19
SARS-CoV-2
coronavirus
subacute thyroiditis
Peru
COVID-19
SARS-CoV-2
coronavirus
tiroiditis subaguda
Perú
title_short THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE
title_full THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE
title_fullStr THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE
title_full_unstemmed THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE
title_sort THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE
author Paz-Ibarra, Jose
author_facet Paz-Ibarra, Jose
author_role author
dc.contributor.author.fl_str_mv Paz-Ibarra, Jose
dc.subject.por.fl_str_mv COVID-19
SARS-CoV-2
coronavirus
subacute thyroiditis
Peru
COVID-19
SARS-CoV-2
coronavirus
tiroiditis subaguda
Perú
topic COVID-19
SARS-CoV-2
coronavirus
subacute thyroiditis
Peru
COVID-19
SARS-CoV-2
coronavirus
tiroiditis subaguda
Perú
description Coronavirus disease compromises all biological organs and systems, either by direct commitment to specific tissues or by indirect effects. The endocrine system is no exception, and parenchyma and thyroid function have been reported to be impaired. In 2003 a histopathological study on the effects of SARS-CoV infection on the thyroid showed extensive damage to parafollicular cells and destruction and exfoliation of epithelial cells in the thyroid follicle, an interesting finding was the absence of an inflammatory infiltrate. which supported the hypothesis of extensive apoptosis responsible for the findings. In China, minimally invasive autopsies of different organs of patients who died of SARS-CoV-2 did not report abnormalities in thyroid follicular morphology, but noted lymphocytic infiltration in the interstitium; none of the tissue immunohistochemistry and PCR analyzes detected SARS-CoV-2 in the thyroid. The first case of thyroid alteration compatible with subacute thyroiditis in a patient with COVID-19 in Peru is presented.
publishDate 2020
dc.date.none.fl_str_mv 2020-07-20
dc.type.driver.fl_str_mv info:eu-repo/semantics/preprint
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format preprint
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://preprints.scielo.org/index.php/scielo/preprint/view/981
10.1590/SciELOPreprints.981
url https://preprints.scielo.org/index.php/scielo/preprint/view/981
identifier_str_mv 10.1590/SciELOPreprints.981
dc.language.iso.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://preprints.scielo.org/index.php/scielo/article/view/981/1391
dc.rights.driver.fl_str_mv Copyright (c) 2020 Jose Paz-Ibarra
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2020 Jose Paz-Ibarra
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv SciELO Preprints
SciELO Preprints
SciELO Preprints
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SciELO Preprints
SciELO Preprints
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repository.mail.fl_str_mv scielo.submission@scielo.org
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