CHARLSON'S COORDINITY INDEX IN SYSTEMIC LUPUS ERYTHEMATOSUS IN BRAZILIAN PATIENTS

• Autor(a) principal: Filipini , Fernando
• Data de Publicação: 2023
• Outros Autores: Andretta, Giuli, Santos, Thiago Alberto, Cuenca, Ronaldo Mafia, Torres, Orlando Jorge Martins, Andreollo , Nelson Adami, Skare, Thelma Larocca
• Tipo de documento: preprint
• Idioma: por
• Título da fonte: SciELO Preprints
• Texto Completo: https://preprints.scielo.org/index.php/scielo/preprint/view/6707
• topic: Lúpus eritematoso sistêmico; Sobrevida; Índice de comorbidades de Charlson; Prognóstico; Lupus erythematosus, systemic; Survival; Charlson’s comorbidities index; Prognosis

Introduction: The Charlson comorbidities index (CCI) assesses a person's chances of survival over the next 10 years. In systemic lupus erythematosus (SLE), multiple comorbidities and complications affect patient survival. Objetive: Analize the variables that influence the CCI of a group of females with SLE. Methods: Retrospective study of medical records of 100 lupus patients for CCI, clinical, epidemiological and serological variables. Results: No epidemiological variable interfered in CCI. Regarding clinical manifestations, patients with glomerulonephritis had a worse CCI than those without (p<0.0001) and those with central nervous system manifestations had a tendency to worse CCI (p=0.09). Patients with anti-Ro antibodies (p=0.02) and rheumatoid factor or RF (p=0.002) were associated with a lower CCI. Conclusions: The presence of glomerulonephritis is associated with lower survival and of the anti-Ro and RF antibodies with longer survival in SLE.