Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospital

Detalhes bibliográficos
Autor(a) principal: Studart-Neto, Adalberto
Data de Publicação: 2020
Outros Autores: Guedes, Bruno Fukelmann, Tuma, Raphael De Luca E, Camelo Filho, Antonio Edvan, Kubota, Gabriel Taricani, Iepsen, Bruno Diógenes, Moreira, Gabriela Pantaleão, Rodrigues, Júlia Chartouni, Ferrari, Maíra Medeiros Honorato, Carra, Rafael Bernhard, Spera, Raphael Ribeiro, Oku, Mariana Hiromi Manoel, Terrim, Sara, Lopes, Cesar Castello Branco, Passos Neto, Carlos Eduardo Borges, Dalben, Matheus, De Souza, Julia Carvalhinho Carlos, Baima, José Pedro Soares, Da Silva, Tomás Fraga Ferreira, Moreno, Cristiane Araujo Martins, Silva, Andre Macedo Serafim, Heise, Carlos Otto, Mendonça, Rodrigo Holanda, Fortini, Ida, Smid, Jerusa, Adoni, Tarso, Gonçalves, Marcia Rubia Rodrigues, Pereira, Samira Luisa Apóstolos, Pinto, Lecio Figueira, Gomes, Helio Rodrigues, Zanotelli, Edmar, Brucki, Sonia Maria Dozzi, Conforto, Adriana Bastos, Castro, Luiz Henrique Martins, Nitrini, Ricardo
Tipo de documento: preprint
Idioma: eng
Título da fonte: SciELO Preprints
Texto Completo: https://preprints.scielo.org/index.php/scielo/preprint/view/971
Resumo: Background: More than one-third of COVID-19 patients present neurological symptomsranging from anosmia to stroke and encephalopathy. Furthermore, pre-existingneurological conditions may require special treatment and may be associated with worseoutcomes. Notwithstanding, the role of neurologists in COVID-19 is probablyunderrecognized. Objective: The aim of this study was to report the reasons forrequesting neurological consultations by internists and intensivists in a COVID-19-dedicated hospital. Methods: This retrospective study was carried out at Hospital dasClínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil, a 900-bedCOVID-19 dedicated center (including 300 intensive care unit beds). COVID-19 diagnosiswas confirmed by SARS-CoV-2-RT-PCR in nasal swabs. All inpatient neurologyconsultations between March 23rd and May 23rd, 2020 were analyzed. Neurologistsperformed the neurological exam, assessed all available data to diagnose theneurological condition, and requested additional tests deemed necessary. Difficultdiagnoses were established in consensus meetings. After diagnosis, neurologists wereinvolved in the treatment. Results: Neurological consultations were requested for 89 outof 1,208 (7.4%) inpatient COVID admissions during that period. Main neurologicaldiagnoses included: encephalopathy (44.4%), stroke (16.7%), previous neurologicaldiseases (9.0%), seizures (9.0%), neuromuscular disorders (5.6%), other acute brainlesions (3.4%), and other mild nonspecific symptoms (11.2%). Conclusions: Mostneurological consultations in a COVID-19-dedicated hospital were requested for severeconditions that could have an impact on the outcome. First-line doctors should be able torecognize neurological symptoms; neurologists are important members of the medicalteam in COVID-19 hospital care.
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spelling Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospitalConsultas neurológicas e diagnósticos em um grande hospital universitário dedicado a COVID-19Infecções por CoronavírusCOVID-19NeurologiaConvulsõesAcidente Vascular CerebralEncefalopatiasDoenças NeuromuscularesCoronavirus InfectionsCOVID-19NeurologySeizuresStrokeMetabolic EncephalopathyNeuromuscular DiseasesBackground: More than one-third of COVID-19 patients present neurological symptomsranging from anosmia to stroke and encephalopathy. Furthermore, pre-existingneurological conditions may require special treatment and may be associated with worseoutcomes. Notwithstanding, the role of neurologists in COVID-19 is probablyunderrecognized. Objective: The aim of this study was to report the reasons forrequesting neurological consultations by internists and intensivists in a COVID-19-dedicated hospital. Methods: This retrospective study was carried out at Hospital dasClínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil, a 900-bedCOVID-19 dedicated center (including 300 intensive care unit beds). COVID-19 diagnosiswas confirmed by SARS-CoV-2-RT-PCR in nasal swabs. All inpatient neurologyconsultations between March 23rd and May 23rd, 2020 were analyzed. Neurologistsperformed the neurological exam, assessed all available data to diagnose theneurological condition, and requested additional tests deemed necessary. Difficultdiagnoses were established in consensus meetings. After diagnosis, neurologists wereinvolved in the treatment. Results: Neurological consultations were requested for 89 outof 1,208 (7.4%) inpatient COVID admissions during that period. Main neurologicaldiagnoses included: encephalopathy (44.4%), stroke (16.7%), previous neurologicaldiseases (9.0%), seizures (9.0%), neuromuscular disorders (5.6%), other acute brainlesions (3.4%), and other mild nonspecific symptoms (11.2%). Conclusions: Mostneurological consultations in a COVID-19-dedicated hospital were requested for severeconditions that could have an impact on the outcome. First-line doctors should be able torecognize neurological symptoms; neurologists are important members of the medicalteam in COVID-19 hospital care.Introdução: Mais de um terço dos pacientes com COVID-19 apresentam sintomasneurológicos que variam de anosmia a AVC e encefalopatia. Além disso, doençasneurológicas prévias podem exigir tratamento especial e estar associadas a pioresdesfechos. Não obstante, o papel dos neurologistas na COVID-19 é provavelmentepouco reconhecido. Objetivo: O objetivo deste estudo foi relatar os motivos para solicitarconsultas neurológicas por clínicos e intensivistas em um hospital dedicado à COVID-19. Métodos: Estudo retrospectivo realizado no Hospital das Clínicas da Faculdade deMedicina da Universidade de São Paulo, Brasil, um centro dedicado à COVID-19 com900 leitos (incluindo 300 leitos para unidades de terapia intensiva). O diagnóstico deCOVID-19 foi confirmado por SARS-CoV-2-RT-PCR em swabs nasais. Todas asinterconsultas de neurologia hospitalar entre 23 de março e 23 de maio de 2020 foramanalisadas. Os neurologistas realizaram o exame neurológico, avaliaram todos os dadosdisponíveis para diagnosticar a patologia neurológica e solicitaram exames adicionaisconforme necessidade. Diagnósticos difíceis foram estabelecidos em reuniões deconsenso. Após o diagnóstico, os neurologistas participaram da condução dos casos.Resultados: Foram solicitadas consultas neurológicas para 89 de 1.208 (7,4%) empacientes internados por COVID-19 durante o período. Os principais diagnósticosneurológicos incluíram: encefalopatia (44,4%), acidente vascular cerebral (16,7%),doenças neurológicas prévias (9,0%), crises epilépticas (9,0%), transtornosneuromusculares (5,6%), outras lesões encefálicas agudas (3,4%) e outros sintomasleves inespecíficos (11,2%). Conclusões: A maioria das consultas neurológicas em umhospital dedicado à COVID-19 foi solicitada para condições graves que poderiam afetaro desfecho clínico. Os médicos na linha de frente devem ser capazes de reconhecersintomas neurológicos. Os neurologistas são membros importantes da equipe médica noatendimento hospitalar à COVID-19.SciELO PreprintsSciELO PreprintsSciELO Preprints2020-07-16info:eu-repo/semantics/preprintinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://preprints.scielo.org/index.php/scielo/preprint/view/97110.1590/0004-282X20200089enghttps://preprints.scielo.org/index.php/scielo/article/view/971/1389Copyright (c) 2020 Adalberto Studart-Neto, Bruno Fukelmann Guedes, Raphael De Luca E Tuma, Antonio Edvan Camelo Filho, Gabriel Taricani Kubota, Bruno Diógenes Iepsen, Gabriela Pantaleão Moreira, Júlia Chartouni Rodrigues, Maíra Medeiros Honorato Ferrari, Rafael Bernhard Carra, Raphael Ribeiro Spera, Mariana Hiromi Manoel Oku, Sara Terrim, Cesar Castello Branco Lopes, Carlos Eduardo Borges Passos Neto, Matheus Dalben, Julia Carvalhinho Carlos De Souza, José Pedro Soares Baima, Tomás Fraga Ferreira Da Silva, Cristiane Araujo Martins Moreno, Andre Macedo Serafim Silva, Carlos Otto Heise, Rodrigo Holanda Mendonça, Ida Fortini, Jerusa Smid, Tarso Adoni, Marcia Rubia Rodrigues Gonçalves, Samira Luisa Apóstolos Pereira, Lecio Figueira Pinto, Helio Rodrigues Gomes, Edmar Zanotelli, Sonia Maria Dozzi Brucki, Adriana Bastos Conforto, Luiz Henrique Martins Castro, Ricardo Nitrinihttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessStudart-Neto, Adalberto Guedes, Bruno Fukelmann Tuma, Raphael De Luca E Camelo Filho, Antonio Edvan Kubota, Gabriel Taricani Iepsen, Bruno Diógenes Moreira, Gabriela Pantaleão Rodrigues, Júlia Chartouni Ferrari, Maíra Medeiros Honorato Carra, Rafael Bernhard Spera, Raphael Ribeiro Oku, Mariana Hiromi Manoel Terrim, Sara Lopes, Cesar Castello Branco Passos Neto, Carlos Eduardo Borges Dalben, Matheus De Souza, Julia Carvalhinho CarlosBaima, José Pedro Soares Da Silva, Tomás Fraga Ferreira Moreno, Cristiane Araujo Martins Silva, Andre Macedo Serafim Heise, Carlos OttoMendonça, Rodrigo Holanda Fortini, Ida Smid, Jerusa Adoni, Tarso Gonçalves, Marcia Rubia Rodrigues Pereira, Samira Luisa Apóstolos Pinto, Lecio Figueira Gomes, Helio Rodrigues Zanotelli, Edmar Brucki, Sonia Maria Dozzi Conforto, Adriana Bastos Castro, Luiz Henrique Martins Nitrini, Ricardo reponame:SciELO Preprintsinstname:SciELOinstacron:SCI2020-07-16T14:59:09Zoai:ops.preprints.scielo.org:preprint/971Servidor de preprintshttps://preprints.scielo.org/index.php/scieloONGhttps://preprints.scielo.org/index.php/scielo/oaiscielo.submission@scielo.orgopendoar:2020-07-16T14:59:09SciELO Preprints - SciELOfalse
dc.title.none.fl_str_mv Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospital
Consultas neurológicas e diagnósticos em um grande hospital universitário dedicado a COVID-19
title Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospital
spellingShingle Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospital
Studart-Neto, Adalberto
Infecções por Coronavírus
COVID-19
Neurologia
Convulsões
Acidente Vascular Cerebral
Encefalopatias
Doenças Neuromusculares
Coronavirus Infections
COVID-19
Neurology
Seizures
Stroke
Metabolic Encephalopathy
Neuromuscular Diseases
title_short Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospital
title_full Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospital
title_fullStr Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospital
title_full_unstemmed Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospital
title_sort Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospital
author Studart-Neto, Adalberto
author_facet Studart-Neto, Adalberto
Guedes, Bruno Fukelmann
Tuma, Raphael De Luca E
Camelo Filho, Antonio Edvan
Kubota, Gabriel Taricani
Iepsen, Bruno Diógenes
Moreira, Gabriela Pantaleão
Rodrigues, Júlia Chartouni
Ferrari, Maíra Medeiros Honorato
Carra, Rafael Bernhard
Spera, Raphael Ribeiro
Oku, Mariana Hiromi Manoel
Terrim, Sara
Lopes, Cesar Castello Branco
Passos Neto, Carlos Eduardo Borges
Dalben, Matheus
De Souza, Julia Carvalhinho Carlos
Baima, José Pedro Soares
Da Silva, Tomás Fraga Ferreira
Moreno, Cristiane Araujo Martins
Silva, Andre Macedo Serafim
Heise, Carlos Otto
Mendonça, Rodrigo Holanda
Fortini, Ida
Smid, Jerusa
Adoni, Tarso
Gonçalves, Marcia Rubia Rodrigues
Pereira, Samira Luisa Apóstolos
Pinto, Lecio Figueira
Gomes, Helio Rodrigues
Zanotelli, Edmar
Brucki, Sonia Maria Dozzi
Conforto, Adriana Bastos
Castro, Luiz Henrique Martins
Nitrini, Ricardo
author_role author
author2 Guedes, Bruno Fukelmann
Tuma, Raphael De Luca E
Camelo Filho, Antonio Edvan
Kubota, Gabriel Taricani
Iepsen, Bruno Diógenes
Moreira, Gabriela Pantaleão
Rodrigues, Júlia Chartouni
Ferrari, Maíra Medeiros Honorato
Carra, Rafael Bernhard
Spera, Raphael Ribeiro
Oku, Mariana Hiromi Manoel
Terrim, Sara
Lopes, Cesar Castello Branco
Passos Neto, Carlos Eduardo Borges
Dalben, Matheus
De Souza, Julia Carvalhinho Carlos
Baima, José Pedro Soares
Da Silva, Tomás Fraga Ferreira
Moreno, Cristiane Araujo Martins
Silva, Andre Macedo Serafim
Heise, Carlos Otto
Mendonça, Rodrigo Holanda
Fortini, Ida
Smid, Jerusa
Adoni, Tarso
Gonçalves, Marcia Rubia Rodrigues
Pereira, Samira Luisa Apóstolos
Pinto, Lecio Figueira
Gomes, Helio Rodrigues
Zanotelli, Edmar
Brucki, Sonia Maria Dozzi
Conforto, Adriana Bastos
Castro, Luiz Henrique Martins
Nitrini, Ricardo
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Studart-Neto, Adalberto
Guedes, Bruno Fukelmann
Tuma, Raphael De Luca E
Camelo Filho, Antonio Edvan
Kubota, Gabriel Taricani
Iepsen, Bruno Diógenes
Moreira, Gabriela Pantaleão
Rodrigues, Júlia Chartouni
Ferrari, Maíra Medeiros Honorato
Carra, Rafael Bernhard
Spera, Raphael Ribeiro
Oku, Mariana Hiromi Manoel
Terrim, Sara
Lopes, Cesar Castello Branco
Passos Neto, Carlos Eduardo Borges
Dalben, Matheus
De Souza, Julia Carvalhinho Carlos
Baima, José Pedro Soares
Da Silva, Tomás Fraga Ferreira
Moreno, Cristiane Araujo Martins
Silva, Andre Macedo Serafim
Heise, Carlos Otto
Mendonça, Rodrigo Holanda
Fortini, Ida
Smid, Jerusa
Adoni, Tarso
Gonçalves, Marcia Rubia Rodrigues
Pereira, Samira Luisa Apóstolos
Pinto, Lecio Figueira
Gomes, Helio Rodrigues
Zanotelli, Edmar
Brucki, Sonia Maria Dozzi
Conforto, Adriana Bastos
Castro, Luiz Henrique Martins
Nitrini, Ricardo
dc.subject.por.fl_str_mv Infecções por Coronavírus
COVID-19
Neurologia
Convulsões
Acidente Vascular Cerebral
Encefalopatias
Doenças Neuromusculares
Coronavirus Infections
COVID-19
Neurology
Seizures
Stroke
Metabolic Encephalopathy
Neuromuscular Diseases
topic Infecções por Coronavírus
COVID-19
Neurologia
Convulsões
Acidente Vascular Cerebral
Encefalopatias
Doenças Neuromusculares
Coronavirus Infections
COVID-19
Neurology
Seizures
Stroke
Metabolic Encephalopathy
Neuromuscular Diseases
description Background: More than one-third of COVID-19 patients present neurological symptomsranging from anosmia to stroke and encephalopathy. Furthermore, pre-existingneurological conditions may require special treatment and may be associated with worseoutcomes. Notwithstanding, the role of neurologists in COVID-19 is probablyunderrecognized. Objective: The aim of this study was to report the reasons forrequesting neurological consultations by internists and intensivists in a COVID-19-dedicated hospital. Methods: This retrospective study was carried out at Hospital dasClínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil, a 900-bedCOVID-19 dedicated center (including 300 intensive care unit beds). COVID-19 diagnosiswas confirmed by SARS-CoV-2-RT-PCR in nasal swabs. All inpatient neurologyconsultations between March 23rd and May 23rd, 2020 were analyzed. Neurologistsperformed the neurological exam, assessed all available data to diagnose theneurological condition, and requested additional tests deemed necessary. Difficultdiagnoses were established in consensus meetings. After diagnosis, neurologists wereinvolved in the treatment. Results: Neurological consultations were requested for 89 outof 1,208 (7.4%) inpatient COVID admissions during that period. Main neurologicaldiagnoses included: encephalopathy (44.4%), stroke (16.7%), previous neurologicaldiseases (9.0%), seizures (9.0%), neuromuscular disorders (5.6%), other acute brainlesions (3.4%), and other mild nonspecific symptoms (11.2%). Conclusions: Mostneurological consultations in a COVID-19-dedicated hospital were requested for severeconditions that could have an impact on the outcome. First-line doctors should be able torecognize neurological symptoms; neurologists are important members of the medicalteam in COVID-19 hospital care.
publishDate 2020
dc.date.none.fl_str_mv 2020-07-16
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10.1590/0004-282X20200089
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identifier_str_mv 10.1590/0004-282X20200089
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SciELO Preprints
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