Biological, social, and healthcare factors associated with death due to influenza A(H1N1) during the 2009 epidemic in Brazil
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | |
Tipo de documento: | preprint |
Idioma: | eng |
Título da fonte: | SciELO Preprints |
Texto Completo: | https://preprints.scielo.org/index.php/scielo/preprint/view/6696 |
Resumo: | Background: In June 2009, the World Health Organization (WHO) raised the global alert level for the A(H1N1)pdm09 influenza pandemic and at that time sustained transmission in Brazil was established. It was urgent to carry out studies that evaluated possible risk factors for death from Influenza A(H1N1) to improve case management strategies to reduce the lethality of the disease. This study aimed to identify risk factors for death from Influenza A(H1N1), including the effectiveness of the vaccine against influenza A(H1N1) concerning mortality. Methods: A case-control of incident cases of influenza A(H1N1) reported in the Epidemiological Information Systems of the states of São Paulo, Paraná, Pará, Amazonas, and Rio Grande do Sul was conducted. Results: 305 participants were included, 70 of them cases and 235 controls, distributed as follows: Amazonas – 9 cases/10 controls, Pará – 22 cases/77 controls, São Paulo – 19 cases/49 controls, Paraná – 10 cases/54 controls, Rio Grande do Sul – 10 cases/45 controls. These participants had a mean age of 30 years, with 33 years among cases and 25 years among controls. There was a predominance of females both among cases and controls. Biological (age), pre-existing diseases (congestive heart failure, respiratory disease, and diabetes mellitus), and care factors (ICU admission) associated with death from Influenza A(H1N1) were identified. Conclusion: The risk factors identified in this investigation allowed subsidizing the elaboration of clinical conducts, but also indicate important aspects for facing “new” influenza epidemics that are likely to occur in our country. |
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Biological, social, and healthcare factors associated with death due to influenza A(H1N1) during the 2009 epidemic in Brazilinfluenza a virus, h1n1 subtypeDisease outbreakrisk factorscase-control studiesBackground: In June 2009, the World Health Organization (WHO) raised the global alert level for the A(H1N1)pdm09 influenza pandemic and at that time sustained transmission in Brazil was established. It was urgent to carry out studies that evaluated possible risk factors for death from Influenza A(H1N1) to improve case management strategies to reduce the lethality of the disease. This study aimed to identify risk factors for death from Influenza A(H1N1), including the effectiveness of the vaccine against influenza A(H1N1) concerning mortality. Methods: A case-control of incident cases of influenza A(H1N1) reported in the Epidemiological Information Systems of the states of São Paulo, Paraná, Pará, Amazonas, and Rio Grande do Sul was conducted. Results: 305 participants were included, 70 of them cases and 235 controls, distributed as follows: Amazonas – 9 cases/10 controls, Pará – 22 cases/77 controls, São Paulo – 19 cases/49 controls, Paraná – 10 cases/54 controls, Rio Grande do Sul – 10 cases/45 controls. These participants had a mean age of 30 years, with 33 years among cases and 25 years among controls. There was a predominance of females both among cases and controls. Biological (age), pre-existing diseases (congestive heart failure, respiratory disease, and diabetes mellitus), and care factors (ICU admission) associated with death from Influenza A(H1N1) were identified. Conclusion: The risk factors identified in this investigation allowed subsidizing the elaboration of clinical conducts, but also indicate important aspects for facing “new” influenza epidemics that are likely to occur in our country.SciELO PreprintsSciELO PreprintsSciELO Preprints2023-09-15info:eu-repo/semantics/preprintinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://preprints.scielo.org/index.php/scielo/preprint/view/669610.1590/SciELOPreprints.6696enghttps://preprints.scielo.org/index.php/scielo/article/view/6696/12849Copyright (c) 2023 Jose Ueleres Braga, Ana Freitas Ribeirohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBraga, Jose UeleresRibeiro, Ana Freitasreponame:SciELO Preprintsinstname:Scientific Electronic Library Online (SCIELO)instacron:SCI2023-09-11T18:24:22Zoai:ops.preprints.scielo.org:preprint/6696Servidor de preprintshttps://preprints.scielo.org/index.php/scieloONGhttps://preprints.scielo.org/index.php/scielo/oaiscielo.submission@scielo.orgopendoar:2023-09-11T18:24:22SciELO Preprints - Scientific Electronic Library Online (SCIELO)false |
dc.title.none.fl_str_mv |
Biological, social, and healthcare factors associated with death due to influenza A(H1N1) during the 2009 epidemic in Brazil |
title |
Biological, social, and healthcare factors associated with death due to influenza A(H1N1) during the 2009 epidemic in Brazil |
spellingShingle |
Biological, social, and healthcare factors associated with death due to influenza A(H1N1) during the 2009 epidemic in Brazil Braga, Jose Ueleres influenza a virus, h1n1 subtype Disease outbreak risk factors case-control studies |
title_short |
Biological, social, and healthcare factors associated with death due to influenza A(H1N1) during the 2009 epidemic in Brazil |
title_full |
Biological, social, and healthcare factors associated with death due to influenza A(H1N1) during the 2009 epidemic in Brazil |
title_fullStr |
Biological, social, and healthcare factors associated with death due to influenza A(H1N1) during the 2009 epidemic in Brazil |
title_full_unstemmed |
Biological, social, and healthcare factors associated with death due to influenza A(H1N1) during the 2009 epidemic in Brazil |
title_sort |
Biological, social, and healthcare factors associated with death due to influenza A(H1N1) during the 2009 epidemic in Brazil |
author |
Braga, Jose Ueleres |
author_facet |
Braga, Jose Ueleres Ribeiro, Ana Freitas |
author_role |
author |
author2 |
Ribeiro, Ana Freitas |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Braga, Jose Ueleres Ribeiro, Ana Freitas |
dc.subject.por.fl_str_mv |
influenza a virus, h1n1 subtype Disease outbreak risk factors case-control studies |
topic |
influenza a virus, h1n1 subtype Disease outbreak risk factors case-control studies |
description |
Background: In June 2009, the World Health Organization (WHO) raised the global alert level for the A(H1N1)pdm09 influenza pandemic and at that time sustained transmission in Brazil was established. It was urgent to carry out studies that evaluated possible risk factors for death from Influenza A(H1N1) to improve case management strategies to reduce the lethality of the disease. This study aimed to identify risk factors for death from Influenza A(H1N1), including the effectiveness of the vaccine against influenza A(H1N1) concerning mortality. Methods: A case-control of incident cases of influenza A(H1N1) reported in the Epidemiological Information Systems of the states of São Paulo, Paraná, Pará, Amazonas, and Rio Grande do Sul was conducted. Results: 305 participants were included, 70 of them cases and 235 controls, distributed as follows: Amazonas – 9 cases/10 controls, Pará – 22 cases/77 controls, São Paulo – 19 cases/49 controls, Paraná – 10 cases/54 controls, Rio Grande do Sul – 10 cases/45 controls. These participants had a mean age of 30 years, with 33 years among cases and 25 years among controls. There was a predominance of females both among cases and controls. Biological (age), pre-existing diseases (congestive heart failure, respiratory disease, and diabetes mellitus), and care factors (ICU admission) associated with death from Influenza A(H1N1) were identified. Conclusion: The risk factors identified in this investigation allowed subsidizing the elaboration of clinical conducts, but also indicate important aspects for facing “new” influenza epidemics that are likely to occur in our country. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-09-15 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/preprint info:eu-repo/semantics/publishedVersion |
format |
preprint |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://preprints.scielo.org/index.php/scielo/preprint/view/6696 10.1590/SciELOPreprints.6696 |
url |
https://preprints.scielo.org/index.php/scielo/preprint/view/6696 |
identifier_str_mv |
10.1590/SciELOPreprints.6696 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://preprints.scielo.org/index.php/scielo/article/view/6696/12849 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2023 Jose Ueleres Braga, Ana Freitas Ribeiro https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2023 Jose Ueleres Braga, Ana Freitas Ribeiro https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
SciELO Preprints SciELO Preprints SciELO Preprints |
publisher.none.fl_str_mv |
SciELO Preprints SciELO Preprints SciELO Preprints |
dc.source.none.fl_str_mv |
reponame:SciELO Preprints instname:Scientific Electronic Library Online (SCIELO) instacron:SCI |
instname_str |
Scientific Electronic Library Online (SCIELO) |
instacron_str |
SCI |
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SCI |
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SciELO Preprints |
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SciELO Preprints |
repository.name.fl_str_mv |
SciELO Preprints - Scientific Electronic Library Online (SCIELO) |
repository.mail.fl_str_mv |
scielo.submission@scielo.org |
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1797047812828954624 |