Supplementation of prebiotics and probiotics in autistic children: integrative review
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , |
Tipo de documento: | preprint |
Idioma: | por |
Título da fonte: | SciELO Preprints |
Texto Completo: | https://preprints.scielo.org/index.php/scielo/preprint/view/2672 |
Resumo: | Objective: To evaluate the use of probiotics and prebiotics supplementation in autistic children. Data source: Articles were identified in the PubMed and SciELO databases. In order to locate the studies, descriptors in English obtained from the Health Sciences Descriptors (DeCS), were used: Prebiotics. Probiotics. Autism Spectrum Disorder. Gut microbiota. Bifidobacterium. The search was limited to articles in Portuguese and English and comprised the years of publication between 2015-2021. Data synthesis: A total of 6 clinical trials conducted on children with autism have been systematically reviewed. Regarding the types of supplements used, there were 3 studies that used probiotics, 2 that used prebiotics and probiotics and 1 that made only the use of prebiotics. Despite the scarce amount of studies, they have had remarkable results in relation to the supplementation of probiotics and prebiotics in children with ASD. In some studies, it was possible to observe an improvement in the severity of autism and improvements in relation to antisocial behavior, while in others, there was an increase in beneficial bacteria and a decrease in pathogens in the gastrointestinal tract, leading to an improvement in recurrent gastrointestinal symptoms. Conclusions: It is noticeable that the use of prebiotics and probiotics can promote several benefits for people with autism, however studies with a larger number of individuals are necessary and there are standards regarding the intervention regimes. |
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Supplementation of prebiotics and probiotics in autistic children: integrative reviewSuplementação de prebióticos e probióticos em crianças autistas: revisão integrativaautismoprobióticosprebióticossuplementaçãoautismprobioticsprebioticssupplementationObjective: To evaluate the use of probiotics and prebiotics supplementation in autistic children. Data source: Articles were identified in the PubMed and SciELO databases. In order to locate the studies, descriptors in English obtained from the Health Sciences Descriptors (DeCS), were used: Prebiotics. Probiotics. Autism Spectrum Disorder. Gut microbiota. Bifidobacterium. The search was limited to articles in Portuguese and English and comprised the years of publication between 2015-2021. Data synthesis: A total of 6 clinical trials conducted on children with autism have been systematically reviewed. Regarding the types of supplements used, there were 3 studies that used probiotics, 2 that used prebiotics and probiotics and 1 that made only the use of prebiotics. Despite the scarce amount of studies, they have had remarkable results in relation to the supplementation of probiotics and prebiotics in children with ASD. In some studies, it was possible to observe an improvement in the severity of autism and improvements in relation to antisocial behavior, while in others, there was an increase in beneficial bacteria and a decrease in pathogens in the gastrointestinal tract, leading to an improvement in recurrent gastrointestinal symptoms. Conclusions: It is noticeable that the use of prebiotics and probiotics can promote several benefits for people with autism, however studies with a larger number of individuals are necessary and there are standards regarding the intervention regimes.Objetivo: Avaliar o uso da suplementação de probióticos e prebióticos em crianças autistas. Fonte de dados: Foram identificados artigos nas bases de dados PubMed e SciELO. Para a localização dos estudos foram utilizados descritores em inglês cadastrados no Descritores em Ciências da Saúde (DeCS): Prebiotics. Probiotics. Autism Spectrum Disorder. Gut microbiota. Bifidobacterium. A busca limitou-se a artigos em inglês e compreendeu os anos de publicação entre 2015-2021. Síntese de dados: Um total de 6 ensaios clínicos realizados em crianças com autismo foram revisados sistematicamente. Com relação aos tipos de suplementações utilizadas foram 3 estudos que utilizaram probióticos, 2 que utilizaram prebióticos e probióticos e 1 que fez apenas o uso de prebióticos. Apesar da quantidade escassa de estudos, os mesmos tiveram resultados notáveis com relação à suplementação de probióticos e prebióticos em crianças com Transtorno do Espectro Autista. Em alguns estudos foi possível observar a melhora na gravidade do autismo e melhorias com relação ao comportamento antissocial, já em outros houve o aumento de bactérias benéficas e diminuição das patogênicas no trato gastrintestinal levando a melhora de sintomas gastrointestinais recorrentes. Conclusões: É perceptível que o uso de prébióticos e probióticos pode promover diversos benefícios para os portadores de autismo, porém são necessários estudos com um número maior de indivíduos e havendo padrões quanto aos regimes de intervenção.SciELO PreprintsSciELO PreprintsSciELO Preprints2022-01-03info:eu-repo/semantics/preprintinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://preprints.scielo.org/index.php/scielo/preprint/view/267210.1590/SciELOPreprints.2672porhttps://preprints.scielo.org/index.php/scielo/article/view/2672/6052Copyright (c) 2021 Thaynara Lays Sales Brandão, Júlia Carolina Lopes Silva, Jakeline Olindina Francelinohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBrandão, Thaynara Lays SalesSilva, Júlia Carolina LopesFrancelino, Jakeline Olindinareponame:SciELO Preprintsinstname:SciELOinstacron:SCI2021-07-20T22:16:51Zoai:ops.preprints.scielo.org:preprint/2672Servidor de preprintshttps://preprints.scielo.org/index.php/scieloONGhttps://preprints.scielo.org/index.php/scielo/oaiscielo.submission@scielo.orgopendoar:2021-07-20T22:16:51SciELO Preprints - SciELOfalse |
dc.title.none.fl_str_mv |
Supplementation of prebiotics and probiotics in autistic children: integrative review Suplementação de prebióticos e probióticos em crianças autistas: revisão integrativa |
title |
Supplementation of prebiotics and probiotics in autistic children: integrative review |
spellingShingle |
Supplementation of prebiotics and probiotics in autistic children: integrative review Brandão, Thaynara Lays Sales autismo probióticos prebióticos suplementação autism probiotics prebiotics supplementation |
title_short |
Supplementation of prebiotics and probiotics in autistic children: integrative review |
title_full |
Supplementation of prebiotics and probiotics in autistic children: integrative review |
title_fullStr |
Supplementation of prebiotics and probiotics in autistic children: integrative review |
title_full_unstemmed |
Supplementation of prebiotics and probiotics in autistic children: integrative review |
title_sort |
Supplementation of prebiotics and probiotics in autistic children: integrative review |
author |
Brandão, Thaynara Lays Sales |
author_facet |
Brandão, Thaynara Lays Sales Silva, Júlia Carolina Lopes Francelino, Jakeline Olindina |
author_role |
author |
author2 |
Silva, Júlia Carolina Lopes Francelino, Jakeline Olindina |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Brandão, Thaynara Lays Sales Silva, Júlia Carolina Lopes Francelino, Jakeline Olindina |
dc.subject.por.fl_str_mv |
autismo probióticos prebióticos suplementação autism probiotics prebiotics supplementation |
topic |
autismo probióticos prebióticos suplementação autism probiotics prebiotics supplementation |
description |
Objective: To evaluate the use of probiotics and prebiotics supplementation in autistic children. Data source: Articles were identified in the PubMed and SciELO databases. In order to locate the studies, descriptors in English obtained from the Health Sciences Descriptors (DeCS), were used: Prebiotics. Probiotics. Autism Spectrum Disorder. Gut microbiota. Bifidobacterium. The search was limited to articles in Portuguese and English and comprised the years of publication between 2015-2021. Data synthesis: A total of 6 clinical trials conducted on children with autism have been systematically reviewed. Regarding the types of supplements used, there were 3 studies that used probiotics, 2 that used prebiotics and probiotics and 1 that made only the use of prebiotics. Despite the scarce amount of studies, they have had remarkable results in relation to the supplementation of probiotics and prebiotics in children with ASD. In some studies, it was possible to observe an improvement in the severity of autism and improvements in relation to antisocial behavior, while in others, there was an increase in beneficial bacteria and a decrease in pathogens in the gastrointestinal tract, leading to an improvement in recurrent gastrointestinal symptoms. Conclusions: It is noticeable that the use of prebiotics and probiotics can promote several benefits for people with autism, however studies with a larger number of individuals are necessary and there are standards regarding the intervention regimes. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-03 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/preprint info:eu-repo/semantics/publishedVersion |
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preprint |
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publishedVersion |
dc.identifier.uri.fl_str_mv |
https://preprints.scielo.org/index.php/scielo/preprint/view/2672 10.1590/SciELOPreprints.2672 |
url |
https://preprints.scielo.org/index.php/scielo/preprint/view/2672 |
identifier_str_mv |
10.1590/SciELOPreprints.2672 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://preprints.scielo.org/index.php/scielo/article/view/2672/6052 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
SciELO Preprints SciELO Preprints SciELO Preprints |
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SciELO Preprints SciELO Preprints SciELO Preprints |
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SciELO |
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SciELO Preprints - SciELO |
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