Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants

Detalhes bibliográficos
Autor(a) principal: Marquitti, Flavia Maria Darcie
Data de Publicação: 2021
Outros Autores: Coutinho, Renato Mendes, Ferreira, Leonardo Souto, Borges, Marcelo Eduardo, Portella, Tatiana P, Silva, Rafael Lopes Paixão da, Canton, Otavio, Poloni, Silas, Franco, Caroline, Coelho, Verônica, Barberia, Lorena, Bolle, Monica de, Boing, Alexandra Crispim, Donalisio , Maria Rita, Boing, Antonio Fernando, Silva, Antônio Augusto Moura da, Prado, Paulo Inácio, Veras, Maria Amélia de Sousa Mascena, Kraenkel, Roberto
Tipo de documento: preprint
Idioma: por
Título da fonte: SciELO Preprints
Texto Completo: https://preprints.scielo.org/index.php/scielo/preprint/view/2001
Resumo: This letter discusses the epidemic situation of Covid-19 in Brazil, in the face of the emergence of a new strain, called P1, more transmissible and with possible associated reinfection.  Given the collapse of hospital care in Manaus in January 2021 and the results of three recent preprints, all of which found increased transmissibility of the P.1 variant, we propose some urgent actions: the establishment of genomic surveillance based on multi-step diagnostics, starting with RT-PCR type tests  to sequencing; an immediate effort to identify reinfections associated with the new variant, updating its definition protocols; and studies on the efficacy of currently available vaccines in Brazil in respect to the new variant.  We also propose the improvement of the Brazilian health surveillance system, which should be articulated with genomic surveillance, in order to respond more timely to future emergencies. We call on the public agents involved in health surveillance to share data and information regarding the epidemic in a clear, fast and transparent way. Finally, we propose a greater engagement in inter-institutional cooperation of all those involved in the response and production of knowledge about the pandemic in our country.
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spelling Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variantsCarta à Comunidade Científica: o Brasil frente às novas variantes de SARSCoV- 2COVID-19vigilânciap1Covid-19vigilancep1This letter discusses the epidemic situation of Covid-19 in Brazil, in the face of the emergence of a new strain, called P1, more transmissible and with possible associated reinfection.  Given the collapse of hospital care in Manaus in January 2021 and the results of three recent preprints, all of which found increased transmissibility of the P.1 variant, we propose some urgent actions: the establishment of genomic surveillance based on multi-step diagnostics, starting with RT-PCR type tests  to sequencing; an immediate effort to identify reinfections associated with the new variant, updating its definition protocols; and studies on the efficacy of currently available vaccines in Brazil in respect to the new variant.  We also propose the improvement of the Brazilian health surveillance system, which should be articulated with genomic surveillance, in order to respond more timely to future emergencies. We call on the public agents involved in health surveillance to share data and information regarding the epidemic in a clear, fast and transparent way. Finally, we propose a greater engagement in inter-institutional cooperation of all those involved in the response and production of knowledge about the pandemic in our country.Esta carta discute a situação epidêmica da Covid-19 no Brasil frente aoaparecimento de uma nova linhagem, chamada P1, mais transmissível e compossível re-infecção associada. Tendo em vista o colapso do atendimentohospitalar em Manaus em janeiro de 2021 e os resultados de três preprintsrecentes, todos encontrando maior transmissibilidade da variante P.1, propomos algumas ações urgentes: o estabelecimento de uma vigilância genômica baseada em diagnóstico em múltiplos passos, iniciando com os testes do tipo RT-PCR até o sequenciamento; um esforço imediato na identificação de re-infecções associadas à nova variante, atualizando os seus protocolos de definição; e estudos sobre a eficácia das vacinas atualmente disponíveis no Brasil na vigência da nova variante. Propomos, ademais, o aprimoramento do sistema de vigilância em saúde brasileiro, que seja articulado com a vigilância genômica, de forma a responder mais oportunamente a emergências futuras. Chamamos os agentes públicos implicados na vigilância em saúde para que compartilhem dados e informações referentes à epidemia de forma clara, rápida e transparente. Finalmente propomos um maior engajamento na cooperação inter-institucional de todos os envolvidos na resposta e produção de conhecimento sobre a pandemia em nosso país.SciELO PreprintsSciELO PreprintsSciELO Preprints2021-03-23info:eu-repo/semantics/preprintinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://preprints.scielo.org/index.php/scielo/preprint/view/200110.1590/SciELOPreprints.2001porhttps://preprints.scielo.org/index.php/scielo/article/view/2001/3338Copyright (c) 2021 Flavia Maria Darcie Marquitti, Renato Mendes Coutinho, Leonardo Souto Ferreira, Marcelo Eduardo Borges, Tatiana P Portella, Rafael Lopes Paixão da Silva, Otavio Canton, Silas Poloni, Caroline Franco, Verônica Coelho, Lorena Barberia, Monica de Bolle, Alexandra Crispim Boing, Maria Rita Donalisio , Antonio Fernando Boing, Antônio Augusto Moura da Silva, Paulo Inácio Prado, Maria Amélia de Sousa Mascena Veras, Roberto Kraenkelhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMarquitti, Flavia Maria DarcieCoutinho, Renato MendesFerreira, Leonardo SoutoBorges, Marcelo EduardoPortella, Tatiana PSilva, Rafael Lopes Paixão daCanton, OtavioPoloni, SilasFranco, CarolineCoelho, VerônicaBarberia, LorenaBolle, Monica deBoing, Alexandra CrispimDonalisio , Maria RitaBoing, Antonio FernandoSilva, Antônio Augusto Moura daPrado, Paulo InácioVeras, Maria Amélia de Sousa MascenaKraenkel, Robertoreponame:SciELO Preprintsinstname:SciELOinstacron:SCI2021-03-17T21:06:54Zoai:ops.preprints.scielo.org:preprint/2001Servidor de preprintshttps://preprints.scielo.org/index.php/scieloONGhttps://preprints.scielo.org/index.php/scielo/oaiscielo.submission@scielo.orgopendoar:2021-03-17T21:06:54SciELO Preprints - SciELOfalse
dc.title.none.fl_str_mv Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants
Carta à Comunidade Científica: o Brasil frente às novas variantes de SARSCoV- 2
title Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants
spellingShingle Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants
Marquitti, Flavia Maria Darcie
COVID-19
vigilância
p1
Covid-19
vigilance
p1
title_short Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants
title_full Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants
title_fullStr Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants
title_full_unstemmed Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants
title_sort Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants
author Marquitti, Flavia Maria Darcie
author_facet Marquitti, Flavia Maria Darcie
Coutinho, Renato Mendes
Ferreira, Leonardo Souto
Borges, Marcelo Eduardo
Portella, Tatiana P
Silva, Rafael Lopes Paixão da
Canton, Otavio
Poloni, Silas
Franco, Caroline
Coelho, Verônica
Barberia, Lorena
Bolle, Monica de
Boing, Alexandra Crispim
Donalisio , Maria Rita
Boing, Antonio Fernando
Silva, Antônio Augusto Moura da
Prado, Paulo Inácio
Veras, Maria Amélia de Sousa Mascena
Kraenkel, Roberto
author_role author
author2 Coutinho, Renato Mendes
Ferreira, Leonardo Souto
Borges, Marcelo Eduardo
Portella, Tatiana P
Silva, Rafael Lopes Paixão da
Canton, Otavio
Poloni, Silas
Franco, Caroline
Coelho, Verônica
Barberia, Lorena
Bolle, Monica de
Boing, Alexandra Crispim
Donalisio , Maria Rita
Boing, Antonio Fernando
Silva, Antônio Augusto Moura da
Prado, Paulo Inácio
Veras, Maria Amélia de Sousa Mascena
Kraenkel, Roberto
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Marquitti, Flavia Maria Darcie
Coutinho, Renato Mendes
Ferreira, Leonardo Souto
Borges, Marcelo Eduardo
Portella, Tatiana P
Silva, Rafael Lopes Paixão da
Canton, Otavio
Poloni, Silas
Franco, Caroline
Coelho, Verônica
Barberia, Lorena
Bolle, Monica de
Boing, Alexandra Crispim
Donalisio , Maria Rita
Boing, Antonio Fernando
Silva, Antônio Augusto Moura da
Prado, Paulo Inácio
Veras, Maria Amélia de Sousa Mascena
Kraenkel, Roberto
dc.subject.por.fl_str_mv COVID-19
vigilância
p1
Covid-19
vigilance
p1
topic COVID-19
vigilância
p1
Covid-19
vigilance
p1
description This letter discusses the epidemic situation of Covid-19 in Brazil, in the face of the emergence of a new strain, called P1, more transmissible and with possible associated reinfection.  Given the collapse of hospital care in Manaus in January 2021 and the results of three recent preprints, all of which found increased transmissibility of the P.1 variant, we propose some urgent actions: the establishment of genomic surveillance based on multi-step diagnostics, starting with RT-PCR type tests  to sequencing; an immediate effort to identify reinfections associated with the new variant, updating its definition protocols; and studies on the efficacy of currently available vaccines in Brazil in respect to the new variant.  We also propose the improvement of the Brazilian health surveillance system, which should be articulated with genomic surveillance, in order to respond more timely to future emergencies. We call on the public agents involved in health surveillance to share data and information regarding the epidemic in a clear, fast and transparent way. Finally, we propose a greater engagement in inter-institutional cooperation of all those involved in the response and production of knowledge about the pandemic in our country.
publishDate 2021
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identifier_str_mv 10.1590/SciELOPreprints.2001
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dc.relation.none.fl_str_mv https://preprints.scielo.org/index.php/scielo/article/view/2001/3338
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