Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , , , , , , , , |
Tipo de documento: | preprint |
Idioma: | por |
Título da fonte: | SciELO Preprints |
Texto Completo: | https://preprints.scielo.org/index.php/scielo/preprint/view/2001 |
Resumo: | This letter discusses the epidemic situation of Covid-19 in Brazil, in the face of the emergence of a new strain, called P1, more transmissible and with possible associated reinfection. Given the collapse of hospital care in Manaus in January 2021 and the results of three recent preprints, all of which found increased transmissibility of the P.1 variant, we propose some urgent actions: the establishment of genomic surveillance based on multi-step diagnostics, starting with RT-PCR type tests to sequencing; an immediate effort to identify reinfections associated with the new variant, updating its definition protocols; and studies on the efficacy of currently available vaccines in Brazil in respect to the new variant. We also propose the improvement of the Brazilian health surveillance system, which should be articulated with genomic surveillance, in order to respond more timely to future emergencies. We call on the public agents involved in health surveillance to share data and information regarding the epidemic in a clear, fast and transparent way. Finally, we propose a greater engagement in inter-institutional cooperation of all those involved in the response and production of knowledge about the pandemic in our country. |
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Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variantsCarta à Comunidade Científica: o Brasil frente às novas variantes de SARSCoV- 2COVID-19vigilânciap1Covid-19vigilancep1This letter discusses the epidemic situation of Covid-19 in Brazil, in the face of the emergence of a new strain, called P1, more transmissible and with possible associated reinfection. Given the collapse of hospital care in Manaus in January 2021 and the results of three recent preprints, all of which found increased transmissibility of the P.1 variant, we propose some urgent actions: the establishment of genomic surveillance based on multi-step diagnostics, starting with RT-PCR type tests to sequencing; an immediate effort to identify reinfections associated with the new variant, updating its definition protocols; and studies on the efficacy of currently available vaccines in Brazil in respect to the new variant. We also propose the improvement of the Brazilian health surveillance system, which should be articulated with genomic surveillance, in order to respond more timely to future emergencies. We call on the public agents involved in health surveillance to share data and information regarding the epidemic in a clear, fast and transparent way. Finally, we propose a greater engagement in inter-institutional cooperation of all those involved in the response and production of knowledge about the pandemic in our country.Esta carta discute a situação epidêmica da Covid-19 no Brasil frente aoaparecimento de uma nova linhagem, chamada P1, mais transmissível e compossível re-infecção associada. Tendo em vista o colapso do atendimentohospitalar em Manaus em janeiro de 2021 e os resultados de três preprintsrecentes, todos encontrando maior transmissibilidade da variante P.1, propomos algumas ações urgentes: o estabelecimento de uma vigilância genômica baseada em diagnóstico em múltiplos passos, iniciando com os testes do tipo RT-PCR até o sequenciamento; um esforço imediato na identificação de re-infecções associadas à nova variante, atualizando os seus protocolos de definição; e estudos sobre a eficácia das vacinas atualmente disponíveis no Brasil na vigência da nova variante. Propomos, ademais, o aprimoramento do sistema de vigilância em saúde brasileiro, que seja articulado com a vigilância genômica, de forma a responder mais oportunamente a emergências futuras. Chamamos os agentes públicos implicados na vigilância em saúde para que compartilhem dados e informações referentes à epidemia de forma clara, rápida e transparente. Finalmente propomos um maior engajamento na cooperação inter-institucional de todos os envolvidos na resposta e produção de conhecimento sobre a pandemia em nosso país.SciELO PreprintsSciELO PreprintsSciELO Preprints2021-03-23info:eu-repo/semantics/preprintinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://preprints.scielo.org/index.php/scielo/preprint/view/200110.1590/SciELOPreprints.2001porhttps://preprints.scielo.org/index.php/scielo/article/view/2001/3338Copyright (c) 2021 Flavia Maria Darcie Marquitti, Renato Mendes Coutinho, Leonardo Souto Ferreira, Marcelo Eduardo Borges, Tatiana P Portella, Rafael Lopes Paixão da Silva, Otavio Canton, Silas Poloni, Caroline Franco, Verônica Coelho, Lorena Barberia, Monica de Bolle, Alexandra Crispim Boing, Maria Rita Donalisio , Antonio Fernando Boing, Antônio Augusto Moura da Silva, Paulo Inácio Prado, Maria Amélia de Sousa Mascena Veras, Roberto Kraenkelhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMarquitti, Flavia Maria DarcieCoutinho, Renato MendesFerreira, Leonardo SoutoBorges, Marcelo EduardoPortella, Tatiana PSilva, Rafael Lopes Paixão daCanton, OtavioPoloni, SilasFranco, CarolineCoelho, VerônicaBarberia, LorenaBolle, Monica deBoing, Alexandra CrispimDonalisio , Maria RitaBoing, Antonio FernandoSilva, Antônio Augusto Moura daPrado, Paulo InácioVeras, Maria Amélia de Sousa MascenaKraenkel, Robertoreponame:SciELO Preprintsinstname:SciELOinstacron:SCI2021-03-17T21:06:54Zoai:ops.preprints.scielo.org:preprint/2001Servidor de preprintshttps://preprints.scielo.org/index.php/scieloONGhttps://preprints.scielo.org/index.php/scielo/oaiscielo.submission@scielo.orgopendoar:2021-03-17T21:06:54SciELO Preprints - SciELOfalse |
dc.title.none.fl_str_mv |
Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants Carta à Comunidade Científica: o Brasil frente às novas variantes de SARSCoV- 2 |
title |
Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants |
spellingShingle |
Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants Marquitti, Flavia Maria Darcie COVID-19 vigilância p1 Covid-19 vigilance p1 |
title_short |
Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants |
title_full |
Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants |
title_fullStr |
Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants |
title_full_unstemmed |
Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants |
title_sort |
Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants |
author |
Marquitti, Flavia Maria Darcie |
author_facet |
Marquitti, Flavia Maria Darcie Coutinho, Renato Mendes Ferreira, Leonardo Souto Borges, Marcelo Eduardo Portella, Tatiana P Silva, Rafael Lopes Paixão da Canton, Otavio Poloni, Silas Franco, Caroline Coelho, Verônica Barberia, Lorena Bolle, Monica de Boing, Alexandra Crispim Donalisio , Maria Rita Boing, Antonio Fernando Silva, Antônio Augusto Moura da Prado, Paulo Inácio Veras, Maria Amélia de Sousa Mascena Kraenkel, Roberto |
author_role |
author |
author2 |
Coutinho, Renato Mendes Ferreira, Leonardo Souto Borges, Marcelo Eduardo Portella, Tatiana P Silva, Rafael Lopes Paixão da Canton, Otavio Poloni, Silas Franco, Caroline Coelho, Verônica Barberia, Lorena Bolle, Monica de Boing, Alexandra Crispim Donalisio , Maria Rita Boing, Antonio Fernando Silva, Antônio Augusto Moura da Prado, Paulo Inácio Veras, Maria Amélia de Sousa Mascena Kraenkel, Roberto |
author2_role |
author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Marquitti, Flavia Maria Darcie Coutinho, Renato Mendes Ferreira, Leonardo Souto Borges, Marcelo Eduardo Portella, Tatiana P Silva, Rafael Lopes Paixão da Canton, Otavio Poloni, Silas Franco, Caroline Coelho, Verônica Barberia, Lorena Bolle, Monica de Boing, Alexandra Crispim Donalisio , Maria Rita Boing, Antonio Fernando Silva, Antônio Augusto Moura da Prado, Paulo Inácio Veras, Maria Amélia de Sousa Mascena Kraenkel, Roberto |
dc.subject.por.fl_str_mv |
COVID-19 vigilância p1 Covid-19 vigilance p1 |
topic |
COVID-19 vigilância p1 Covid-19 vigilance p1 |
description |
This letter discusses the epidemic situation of Covid-19 in Brazil, in the face of the emergence of a new strain, called P1, more transmissible and with possible associated reinfection. Given the collapse of hospital care in Manaus in January 2021 and the results of three recent preprints, all of which found increased transmissibility of the P.1 variant, we propose some urgent actions: the establishment of genomic surveillance based on multi-step diagnostics, starting with RT-PCR type tests to sequencing; an immediate effort to identify reinfections associated with the new variant, updating its definition protocols; and studies on the efficacy of currently available vaccines in Brazil in respect to the new variant. We also propose the improvement of the Brazilian health surveillance system, which should be articulated with genomic surveillance, in order to respond more timely to future emergencies. We call on the public agents involved in health surveillance to share data and information regarding the epidemic in a clear, fast and transparent way. Finally, we propose a greater engagement in inter-institutional cooperation of all those involved in the response and production of knowledge about the pandemic in our country. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-03-23 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/preprint info:eu-repo/semantics/publishedVersion |
format |
preprint |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://preprints.scielo.org/index.php/scielo/preprint/view/2001 10.1590/SciELOPreprints.2001 |
url |
https://preprints.scielo.org/index.php/scielo/preprint/view/2001 |
identifier_str_mv |
10.1590/SciELOPreprints.2001 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://preprints.scielo.org/index.php/scielo/article/view/2001/3338 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
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application/pdf |
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SciELO Preprints SciELO Preprints SciELO Preprints |
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SciELO Preprints SciELO Preprints SciELO Preprints |
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SciELO Preprints - SciELO |
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