Vitamin E and Solid Lipid Nanoparticles (NLSs): partners in the diabetic wound healing.
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Revista Enfermagem Atual In Derme |
Texto Completo: | https://revistaenfermagematual.com/index.php/revista/article/view/786 |
Resumo: | Diabetic foot affects 4 to 10% of diabetic patients per year and has a high rate of amputation and mortality (39-80%). Diabetes Mellitus (DM) is among the chronic diseases that increase reactive oxygen molecular species (ROS) generation by glucose oxidation. Antioxidants-associated lipid nanocarriers is a promising tool in the diabetic healing treatment. The mini-review aim is to introduce the pathophysiological and how vitamin E-mechanism could be to prevent and treat this diabetic wound, as well as the solid lipid nanocarriers (SLN), which can help accelerate the impaired diabetic wound healing process when associated with vitamin E. |
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Vitamin E and Solid Lipid Nanoparticles (NLSs): partners in the diabetic wound healing.Vitamina E e Nanopartículas Lipídicas Sólidas (NLSs): parceiras na cicatrização da ferida diabética.DiabetesFeridasVitamina ENanocarreadores Lipídicos Sólidos (NLS)Estresse OxidativoDiabetesWoundVitamin ESolid Lipid Nanocarriers (SLN)Oxidative StressDiabetic foot affects 4 to 10% of diabetic patients per year and has a high rate of amputation and mortality (39-80%). Diabetes Mellitus (DM) is among the chronic diseases that increase reactive oxygen molecular species (ROS) generation by glucose oxidation. Antioxidants-associated lipid nanocarriers is a promising tool in the diabetic healing treatment. The mini-review aim is to introduce the pathophysiological and how vitamin E-mechanism could be to prevent and treat this diabetic wound, as well as the solid lipid nanocarriers (SLN), which can help accelerate the impaired diabetic wound healing process when associated with vitamin E. O pé diabético acomete de 4 a 10% dos pacientes diabéticos por ano, e apresenta um alto índice de amputação e mortalidade (39-80%). O diabetes mellius (DM) está dentre as doenças crônicas que aumentam a geração das espécies moleculares reativas de oxigênio (EROs) pela oxidação da glicose. O uso de antioxidantes associados a nanocarreadores lipídicos é uma ferramenta promissora no tratamento da cicatrização diabética deficiente. O objetivo dessa mini-review é apresentar o mecanismo fisiopatológico e como a vitamina E atua na prevenção e tratamento da ferida diabética, assim como os nanocarreadores lipídicos sólidos (NLS) associados a vitamina E podem auxiliar acelerando o processo de cicatrização deficiente da ferida diabética. SOBENFeE2021-02-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdftext/plaintext/plainhttps://revistaenfermagematual.com/index.php/revista/article/view/78610.31011/reaid-2021-v.95-n.33-art.786Journal Enfermagem Atual In Derme; Vol. 95 No. 33 (2021): Jan. Fev. Mar.; e-021023Revista Enfermagem Atual In Derme; v. 95 n. 33 (2021): Jan. Fev. Mar.; e-0210232447-2034reponame:Revista Enfermagem Atual In Dermeinstname:Sociedade Brasileira de Enfermagem em Feridas e Estética (SOBENFeE)instacron:SOBENFeEporenghttps://revistaenfermagematual.com/index.php/revista/article/view/786/825https://revistaenfermagematual.com/index.php/revista/article/view/786/835https://revistaenfermagematual.com/index.php/revista/article/view/786/1117https://revistaenfermagematual.com/index.php/revista/article/view/786/1121Copyright (c) 2021 Revista Enfermagem Atual In Dermeinfo:eu-repo/semantics/openAccessPessoa, Ana Flavia MarçalAmaral, Bruna Karla DoBlanck, Maria Da Conceição Baldini BenevidesSilva, Silvia Sousa dePedrosa, Adelso AparecidoMartins, Camila SafranskiOtoch, José Pinhata2023-12-26T12:53:29Zoai:revistae_ojs.revistaenfermagematual.a2hosted.com:article/786Revistahttps://revistaenfermagematual.com/index.php/revista/indexONGhttps://revistaenfermagematual.com/index.php/revista/oaikatia.simoes@gmail.com || contato@revistaenfermagematual.com.br2447-20342447-2034opendoar:2023-12-26T12:53:29Revista Enfermagem Atual In Derme - Sociedade Brasileira de Enfermagem em Feridas e Estética (SOBENFeE)false |
dc.title.none.fl_str_mv |
Vitamin E and Solid Lipid Nanoparticles (NLSs): partners in the diabetic wound healing. Vitamina E e Nanopartículas Lipídicas Sólidas (NLSs): parceiras na cicatrização da ferida diabética. |
title |
Vitamin E and Solid Lipid Nanoparticles (NLSs): partners in the diabetic wound healing. |
spellingShingle |
Vitamin E and Solid Lipid Nanoparticles (NLSs): partners in the diabetic wound healing. Pessoa, Ana Flavia Marçal Diabetes Feridas Vitamina E Nanocarreadores Lipídicos Sólidos (NLS) Estresse Oxidativo Diabetes Wound Vitamin E Solid Lipid Nanocarriers (SLN) Oxidative Stress |
title_short |
Vitamin E and Solid Lipid Nanoparticles (NLSs): partners in the diabetic wound healing. |
title_full |
Vitamin E and Solid Lipid Nanoparticles (NLSs): partners in the diabetic wound healing. |
title_fullStr |
Vitamin E and Solid Lipid Nanoparticles (NLSs): partners in the diabetic wound healing. |
title_full_unstemmed |
Vitamin E and Solid Lipid Nanoparticles (NLSs): partners in the diabetic wound healing. |
title_sort |
Vitamin E and Solid Lipid Nanoparticles (NLSs): partners in the diabetic wound healing. |
author |
Pessoa, Ana Flavia Marçal |
author_facet |
Pessoa, Ana Flavia Marçal Amaral, Bruna Karla Do Blanck, Maria Da Conceição Baldini Benevides Silva, Silvia Sousa de Pedrosa, Adelso Aparecido Martins, Camila Safranski Otoch, José Pinhata |
author_role |
author |
author2 |
Amaral, Bruna Karla Do Blanck, Maria Da Conceição Baldini Benevides Silva, Silvia Sousa de Pedrosa, Adelso Aparecido Martins, Camila Safranski Otoch, José Pinhata |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Pessoa, Ana Flavia Marçal Amaral, Bruna Karla Do Blanck, Maria Da Conceição Baldini Benevides Silva, Silvia Sousa de Pedrosa, Adelso Aparecido Martins, Camila Safranski Otoch, José Pinhata |
dc.subject.por.fl_str_mv |
Diabetes Feridas Vitamina E Nanocarreadores Lipídicos Sólidos (NLS) Estresse Oxidativo Diabetes Wound Vitamin E Solid Lipid Nanocarriers (SLN) Oxidative Stress |
topic |
Diabetes Feridas Vitamina E Nanocarreadores Lipídicos Sólidos (NLS) Estresse Oxidativo Diabetes Wound Vitamin E Solid Lipid Nanocarriers (SLN) Oxidative Stress |
description |
Diabetic foot affects 4 to 10% of diabetic patients per year and has a high rate of amputation and mortality (39-80%). Diabetes Mellitus (DM) is among the chronic diseases that increase reactive oxygen molecular species (ROS) generation by glucose oxidation. Antioxidants-associated lipid nanocarriers is a promising tool in the diabetic healing treatment. The mini-review aim is to introduce the pathophysiological and how vitamin E-mechanism could be to prevent and treat this diabetic wound, as well as the solid lipid nanocarriers (SLN), which can help accelerate the impaired diabetic wound healing process when associated with vitamin E. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-02-04 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistaenfermagematual.com/index.php/revista/article/view/786 10.31011/reaid-2021-v.95-n.33-art.786 |
url |
https://revistaenfermagematual.com/index.php/revista/article/view/786 |
identifier_str_mv |
10.31011/reaid-2021-v.95-n.33-art.786 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://revistaenfermagematual.com/index.php/revista/article/view/786/825 https://revistaenfermagematual.com/index.php/revista/article/view/786/835 https://revistaenfermagematual.com/index.php/revista/article/view/786/1117 https://revistaenfermagematual.com/index.php/revista/article/view/786/1121 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2021 Revista Enfermagem Atual In Derme info:eu-repo/semantics/openAccess |
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Copyright (c) 2021 Revista Enfermagem Atual In Derme |
eu_rights_str_mv |
openAccess |
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application/pdf application/pdf text/plain text/plain |
dc.publisher.none.fl_str_mv |
SOBENFeE |
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Journal Enfermagem Atual In Derme; Vol. 95 No. 33 (2021): Jan. Fev. Mar.; e-021023 Revista Enfermagem Atual In Derme; v. 95 n. 33 (2021): Jan. Fev. Mar.; e-021023 2447-2034 reponame:Revista Enfermagem Atual In Derme instname:Sociedade Brasileira de Enfermagem em Feridas e Estética (SOBENFeE) instacron:SOBENFeE |
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Sociedade Brasileira de Enfermagem em Feridas e Estética (SOBENFeE) |
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Revista Enfermagem Atual In Derme |
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Revista Enfermagem Atual In Derme - Sociedade Brasileira de Enfermagem em Feridas e Estética (SOBENFeE) |
repository.mail.fl_str_mv |
katia.simoes@gmail.com || contato@revistaenfermagematual.com.br |
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