Comparisons between continuous and batch processing to produce clavulanic acid by Streptomyces clavuligerus

Detalhes bibliográficos
Autor(a) principal: Baptista-Neto,Álvaro
Data de Publicação: 2005
Outros Autores: Teodoro,Juliana Conceição, Cassiano Filho,Luiz Claudio Macedo, Badino,Alberto Colli, Hokka,Carlos Osamu
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000400012
Resumo: The aim of the present work was to compare CA production in continuous culture with and without cell recycling and in batch process by Streptomyces clavuligerus. Continuous cultivations with high cell concentration using cell recycling were performed utilizing a hollow fiber ultrafiltration module to separate cells from the filtrate broth. The continuous cultures without cell recycling and the batch cultivations were performed conventionally. The highest productivity was attained in the continuous cultivation with cell recycling (22.2 mg.L-1.h-1). The highest CA concentration was obtained in the batch process (470 mg.L-1.h-1).
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spelling Comparisons between continuous and batch processing to produce clavulanic acid by Streptomyces clavuligerusClavulanic acidStreptomyces clavuligeruscontinuous cultureThe aim of the present work was to compare CA production in continuous culture with and without cell recycling and in batch process by Streptomyces clavuligerus. Continuous cultivations with high cell concentration using cell recycling were performed utilizing a hollow fiber ultrafiltration module to separate cells from the filtrate broth. The continuous cultures without cell recycling and the batch cultivations were performed conventionally. The highest productivity was attained in the continuous cultivation with cell recycling (22.2 mg.L-1.h-1). The highest CA concentration was obtained in the batch process (470 mg.L-1.h-1).Instituto de Tecnologia do Paraná - Tecpar2005-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000400012Brazilian Archives of Biology and Technology v.48 n.spe 2005reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132005000400012info:eu-repo/semantics/openAccessBaptista-Neto,ÁlvaroTeodoro,Juliana ConceiçãoCassiano Filho,Luiz Claudio MacedoBadino,Alberto ColliHokka,Carlos Osamueng2005-08-15T00:00:00Zoai:scielo:S1516-89132005000400012Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2005-08-15T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Comparisons between continuous and batch processing to produce clavulanic acid by Streptomyces clavuligerus
title Comparisons between continuous and batch processing to produce clavulanic acid by Streptomyces clavuligerus
spellingShingle Comparisons between continuous and batch processing to produce clavulanic acid by Streptomyces clavuligerus
Baptista-Neto,Álvaro
Clavulanic acid
Streptomyces clavuligerus
continuous culture
title_short Comparisons between continuous and batch processing to produce clavulanic acid by Streptomyces clavuligerus
title_full Comparisons between continuous and batch processing to produce clavulanic acid by Streptomyces clavuligerus
title_fullStr Comparisons between continuous and batch processing to produce clavulanic acid by Streptomyces clavuligerus
title_full_unstemmed Comparisons between continuous and batch processing to produce clavulanic acid by Streptomyces clavuligerus
title_sort Comparisons between continuous and batch processing to produce clavulanic acid by Streptomyces clavuligerus
author Baptista-Neto,Álvaro
author_facet Baptista-Neto,Álvaro
Teodoro,Juliana Conceição
Cassiano Filho,Luiz Claudio Macedo
Badino,Alberto Colli
Hokka,Carlos Osamu
author_role author
author2 Teodoro,Juliana Conceição
Cassiano Filho,Luiz Claudio Macedo
Badino,Alberto Colli
Hokka,Carlos Osamu
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Baptista-Neto,Álvaro
Teodoro,Juliana Conceição
Cassiano Filho,Luiz Claudio Macedo
Badino,Alberto Colli
Hokka,Carlos Osamu
dc.subject.por.fl_str_mv Clavulanic acid
Streptomyces clavuligerus
continuous culture
topic Clavulanic acid
Streptomyces clavuligerus
continuous culture
description The aim of the present work was to compare CA production in continuous culture with and without cell recycling and in batch process by Streptomyces clavuligerus. Continuous cultivations with high cell concentration using cell recycling were performed utilizing a hollow fiber ultrafiltration module to separate cells from the filtrate broth. The continuous cultures without cell recycling and the batch cultivations were performed conventionally. The highest productivity was attained in the continuous cultivation with cell recycling (22.2 mg.L-1.h-1). The highest CA concentration was obtained in the batch process (470 mg.L-1.h-1).
publishDate 2005
dc.date.none.fl_str_mv 2005-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000400012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000400012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132005000400012
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.48 n.spe 2005
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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