Incorporation of n-3 fatty acids by the liver of mice fed linseed oil as a function of feeding duration

Detalhes bibliográficos
Autor(a) principal: Perini,João Angelo Lima
Data de Publicação: 2011
Outros Autores: Stevanato,Flávia Braidotti, Visentainer,Jeane Eliete Laguila, Sargi,Sheisa Cyléia, Oliveira,Marcia Machado, Souza,Nilson Evelázio, Matsushita,Makoto, Visentainer,Jesuí Vergílio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000200012
Resumo: The objective of this study was to evaluate the incorporation of omega-3 fatty acids (n-3 FA) on male Swiss mice livers receiving diets based on linseed oil (LO) for up to 56 days. The mice were sacrificed at 7, 14, 28, 42, 56 days and FA concentration was analyzed by gas chromatography. A total of 13 FA were identified on LO feeds presenting alpha-linolenic acid (LNA) contents of 26.97 %. A total 22 FA were identified in the livers of the mice. Part of the LNA was converted into n-3 FA (20:3n-3, eicosapentaenoic acid-EPA, 22:5n-3, and docosahexaenoic acid-DHA), and some of the LNA was stored in the liver. LNA, EPA and DHA concentrations (mg/g total lipids ) from 0 days for up 56 days increased from 1.29 to 18.90 (LNA), 0.20 to 18.90 (EPA) and 41.26 to 99.17 (DHA).The concentration of n-3 FA in the livers varied with the duration of the LO diet. During LO feed, n-6 FA concentration fell and n-3 FA concentration rose through the experimental period.
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spelling Incorporation of n-3 fatty acids by the liver of mice fed linseed oil as a function of feeding durationpolyunsaturated fatty acidsmiceliverlinseed oilThe objective of this study was to evaluate the incorporation of omega-3 fatty acids (n-3 FA) on male Swiss mice livers receiving diets based on linseed oil (LO) for up to 56 days. The mice were sacrificed at 7, 14, 28, 42, 56 days and FA concentration was analyzed by gas chromatography. A total of 13 FA were identified on LO feeds presenting alpha-linolenic acid (LNA) contents of 26.97 %. A total 22 FA were identified in the livers of the mice. Part of the LNA was converted into n-3 FA (20:3n-3, eicosapentaenoic acid-EPA, 22:5n-3, and docosahexaenoic acid-DHA), and some of the LNA was stored in the liver. LNA, EPA and DHA concentrations (mg/g total lipids ) from 0 days for up 56 days increased from 1.29 to 18.90 (LNA), 0.20 to 18.90 (EPA) and 41.26 to 99.17 (DHA).The concentration of n-3 FA in the livers varied with the duration of the LO diet. During LO feed, n-6 FA concentration fell and n-3 FA concentration rose through the experimental period.Instituto de Tecnologia do Paraná - Tecpar2011-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000200012Brazilian Archives of Biology and Technology v.54 n.2 2011reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132011000200012info:eu-repo/semantics/openAccessPerini,João Angelo LimaStevanato,Flávia BraidottiVisentainer,Jeane Eliete LaguilaSargi,Sheisa CyléiaOliveira,Marcia MachadoSouza,Nilson EvelázioMatsushita,MakotoVisentainer,Jesuí Vergílioeng2011-04-15T00:00:00Zoai:scielo:S1516-89132011000200012Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2011-04-15T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Incorporation of n-3 fatty acids by the liver of mice fed linseed oil as a function of feeding duration
title Incorporation of n-3 fatty acids by the liver of mice fed linseed oil as a function of feeding duration
spellingShingle Incorporation of n-3 fatty acids by the liver of mice fed linseed oil as a function of feeding duration
Perini,João Angelo Lima
polyunsaturated fatty acids
mice
liver
linseed oil
title_short Incorporation of n-3 fatty acids by the liver of mice fed linseed oil as a function of feeding duration
title_full Incorporation of n-3 fatty acids by the liver of mice fed linseed oil as a function of feeding duration
title_fullStr Incorporation of n-3 fatty acids by the liver of mice fed linseed oil as a function of feeding duration
title_full_unstemmed Incorporation of n-3 fatty acids by the liver of mice fed linseed oil as a function of feeding duration
title_sort Incorporation of n-3 fatty acids by the liver of mice fed linseed oil as a function of feeding duration
author Perini,João Angelo Lima
author_facet Perini,João Angelo Lima
Stevanato,Flávia Braidotti
Visentainer,Jeane Eliete Laguila
Sargi,Sheisa Cyléia
Oliveira,Marcia Machado
Souza,Nilson Evelázio
Matsushita,Makoto
Visentainer,Jesuí Vergílio
author_role author
author2 Stevanato,Flávia Braidotti
Visentainer,Jeane Eliete Laguila
Sargi,Sheisa Cyléia
Oliveira,Marcia Machado
Souza,Nilson Evelázio
Matsushita,Makoto
Visentainer,Jesuí Vergílio
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Perini,João Angelo Lima
Stevanato,Flávia Braidotti
Visentainer,Jeane Eliete Laguila
Sargi,Sheisa Cyléia
Oliveira,Marcia Machado
Souza,Nilson Evelázio
Matsushita,Makoto
Visentainer,Jesuí Vergílio
dc.subject.por.fl_str_mv polyunsaturated fatty acids
mice
liver
linseed oil
topic polyunsaturated fatty acids
mice
liver
linseed oil
description The objective of this study was to evaluate the incorporation of omega-3 fatty acids (n-3 FA) on male Swiss mice livers receiving diets based on linseed oil (LO) for up to 56 days. The mice were sacrificed at 7, 14, 28, 42, 56 days and FA concentration was analyzed by gas chromatography. A total of 13 FA were identified on LO feeds presenting alpha-linolenic acid (LNA) contents of 26.97 %. A total 22 FA were identified in the livers of the mice. Part of the LNA was converted into n-3 FA (20:3n-3, eicosapentaenoic acid-EPA, 22:5n-3, and docosahexaenoic acid-DHA), and some of the LNA was stored in the liver. LNA, EPA and DHA concentrations (mg/g total lipids ) from 0 days for up 56 days increased from 1.29 to 18.90 (LNA), 0.20 to 18.90 (EPA) and 41.26 to 99.17 (DHA).The concentration of n-3 FA in the livers varied with the duration of the LO diet. During LO feed, n-6 FA concentration fell and n-3 FA concentration rose through the experimental period.
publishDate 2011
dc.date.none.fl_str_mv 2011-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000200012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000200012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132011000200012
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.54 n.2 2011
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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