Current evaluation of the clinical utility of Fluoromethylcholine-(18F) PET/CT in Prostate Cancer
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Archives of Biology and Technology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700012 |
Resumo: | This short review is dedicated to the current status of the assessment of a new PET radiopharmaceutical, fluoromethylcholine-(18F) or FCH, which is taken-up by prostate cancer tissue, in contrary to fluorodeoxyglucose-(18F) or FDG. It seems that FCH could become "the FDG of prostate cancer", with the same type of achievements (detection of distant metastases and of occult recurrences, restaging prior to invasive treatments), and the same drawbacks (false negative results in case of small lesions, in particular lymph nodes metastases, and false positive results in case of infection/inflammation, in particular prostatitis). Current evidence is summarised and discussed for each of the potential settings of FCH PET/CT imaging in prostate cancer. The perspectives for granting a marketing authorisation to a FCH preparation are briefly analysed. |
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Current evaluation of the clinical utility of Fluoromethylcholine-(18F) PET/CT in Prostate CancerFluoromethylcholine-(18F)PET/CTprostate cancerevaluation of radiopharmaceuticalsThis short review is dedicated to the current status of the assessment of a new PET radiopharmaceutical, fluoromethylcholine-(18F) or FCH, which is taken-up by prostate cancer tissue, in contrary to fluorodeoxyglucose-(18F) or FDG. It seems that FCH could become "the FDG of prostate cancer", with the same type of achievements (detection of distant metastases and of occult recurrences, restaging prior to invasive treatments), and the same drawbacks (false negative results in case of small lesions, in particular lymph nodes metastases, and false positive results in case of infection/inflammation, in particular prostatitis). Current evidence is summarised and discussed for each of the potential settings of FCH PET/CT imaging in prostate cancer. The perspectives for granting a marketing authorisation to a FCH preparation are briefly analysed.Instituto de Tecnologia do Paraná - Tecpar2008-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700012Brazilian Archives of Biology and Technology v.51 n.spe 2008reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132008000700012info:eu-repo/semantics/openAccessTalbot,Jean-NöelChevalme,Yanna-Marinaeng2009-02-20T00:00:00Zoai:scielo:S1516-89132008000700012Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2009-02-20T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false |
dc.title.none.fl_str_mv |
Current evaluation of the clinical utility of Fluoromethylcholine-(18F) PET/CT in Prostate Cancer |
title |
Current evaluation of the clinical utility of Fluoromethylcholine-(18F) PET/CT in Prostate Cancer |
spellingShingle |
Current evaluation of the clinical utility of Fluoromethylcholine-(18F) PET/CT in Prostate Cancer Talbot,Jean-Nöel Fluoromethylcholine-(18F) PET/CT prostate cancer evaluation of radiopharmaceuticals |
title_short |
Current evaluation of the clinical utility of Fluoromethylcholine-(18F) PET/CT in Prostate Cancer |
title_full |
Current evaluation of the clinical utility of Fluoromethylcholine-(18F) PET/CT in Prostate Cancer |
title_fullStr |
Current evaluation of the clinical utility of Fluoromethylcholine-(18F) PET/CT in Prostate Cancer |
title_full_unstemmed |
Current evaluation of the clinical utility of Fluoromethylcholine-(18F) PET/CT in Prostate Cancer |
title_sort |
Current evaluation of the clinical utility of Fluoromethylcholine-(18F) PET/CT in Prostate Cancer |
author |
Talbot,Jean-Nöel |
author_facet |
Talbot,Jean-Nöel Chevalme,Yanna-Marina |
author_role |
author |
author2 |
Chevalme,Yanna-Marina |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Talbot,Jean-Nöel Chevalme,Yanna-Marina |
dc.subject.por.fl_str_mv |
Fluoromethylcholine-(18F) PET/CT prostate cancer evaluation of radiopharmaceuticals |
topic |
Fluoromethylcholine-(18F) PET/CT prostate cancer evaluation of radiopharmaceuticals |
description |
This short review is dedicated to the current status of the assessment of a new PET radiopharmaceutical, fluoromethylcholine-(18F) or FCH, which is taken-up by prostate cancer tissue, in contrary to fluorodeoxyglucose-(18F) or FDG. It seems that FCH could become "the FDG of prostate cancer", with the same type of achievements (detection of distant metastases and of occult recurrences, restaging prior to invasive treatments), and the same drawbacks (false negative results in case of small lesions, in particular lymph nodes metastases, and false positive results in case of infection/inflammation, in particular prostatitis). Current evidence is summarised and discussed for each of the potential settings of FCH PET/CT imaging in prostate cancer. The perspectives for granting a marketing authorisation to a FCH preparation are briefly analysed. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700012 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700012 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1516-89132008000700012 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
dc.source.none.fl_str_mv |
Brazilian Archives of Biology and Technology v.51 n.spe 2008 reponame:Brazilian Archives of Biology and Technology instname:Instituto de Tecnologia do Paraná (Tecpar) instacron:TECPAR |
instname_str |
Instituto de Tecnologia do Paraná (Tecpar) |
instacron_str |
TECPAR |
institution |
TECPAR |
reponame_str |
Brazilian Archives of Biology and Technology |
collection |
Brazilian Archives of Biology and Technology |
repository.name.fl_str_mv |
Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar) |
repository.mail.fl_str_mv |
babt@tecpar.br||babt@tecpar.br |
_version_ |
1750318272669024256 |