The Relationship between Functional and Evolutionary Correlations of Enzyme Reactions in Metabolic Network Evolution

Detalhes bibliográficos
Autor(a) principal: Luo,Hao
Data de Publicação: 2021
Outros Autores: Shen,Tie, Xie,Xiaoyao
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132021000100605
Resumo: Abstract The evolution of species is inevitably accompanied by the evolution of metabolic networks to adapt to different environments. The metabolic networks of different species were collected from the Kyoto Encyclopedia of Genes and Genomes (KEGG) website, and some enzyme reactions with the highest occurrence frequency in all species were found and are reported in this paper. The correlation coefficients of whether the enzyme reactions appear in all species were calculated, and the corresponding evolutionary correlation connection networks were calculated according to different correlation coefficient thresholds. These studies show that, as the evolutionary correlation of enzyme reactions increases, the weighted average of the mean functional concentration ratios of the enzyme reactions also increases, indicating that the functional concentration ratio of enzyme reactions has a certain correlation with the evolutionary correlation. The work presented in this paper enhances our understanding of the characteristics and general rules of metabolic network evolution.
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spelling The Relationship between Functional and Evolutionary Correlations of Enzyme Reactions in Metabolic Network Evolutionmetabolic networkpan-metabolic networkmetabolic network evolutionconnected componentenzyme reactionAbstract The evolution of species is inevitably accompanied by the evolution of metabolic networks to adapt to different environments. The metabolic networks of different species were collected from the Kyoto Encyclopedia of Genes and Genomes (KEGG) website, and some enzyme reactions with the highest occurrence frequency in all species were found and are reported in this paper. The correlation coefficients of whether the enzyme reactions appear in all species were calculated, and the corresponding evolutionary correlation connection networks were calculated according to different correlation coefficient thresholds. These studies show that, as the evolutionary correlation of enzyme reactions increases, the weighted average of the mean functional concentration ratios of the enzyme reactions also increases, indicating that the functional concentration ratio of enzyme reactions has a certain correlation with the evolutionary correlation. The work presented in this paper enhances our understanding of the characteristics and general rules of metabolic network evolution.Instituto de Tecnologia do Paraná - Tecpar2021-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132021000100605Brazilian Archives of Biology and Technology v.64 2021reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/1678-4324-2021190480info:eu-repo/semantics/openAccessLuo,HaoShen,TieXie,Xiaoyaoeng2021-07-02T00:00:00Zoai:scielo:S1516-89132021000100605Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2021-07-02T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv The Relationship between Functional and Evolutionary Correlations of Enzyme Reactions in Metabolic Network Evolution
title The Relationship between Functional and Evolutionary Correlations of Enzyme Reactions in Metabolic Network Evolution
spellingShingle The Relationship between Functional and Evolutionary Correlations of Enzyme Reactions in Metabolic Network Evolution
Luo,Hao
metabolic network
pan-metabolic network
metabolic network evolution
connected component
enzyme reaction
title_short The Relationship between Functional and Evolutionary Correlations of Enzyme Reactions in Metabolic Network Evolution
title_full The Relationship between Functional and Evolutionary Correlations of Enzyme Reactions in Metabolic Network Evolution
title_fullStr The Relationship between Functional and Evolutionary Correlations of Enzyme Reactions in Metabolic Network Evolution
title_full_unstemmed The Relationship between Functional and Evolutionary Correlations of Enzyme Reactions in Metabolic Network Evolution
title_sort The Relationship between Functional and Evolutionary Correlations of Enzyme Reactions in Metabolic Network Evolution
author Luo,Hao
author_facet Luo,Hao
Shen,Tie
Xie,Xiaoyao
author_role author
author2 Shen,Tie
Xie,Xiaoyao
author2_role author
author
dc.contributor.author.fl_str_mv Luo,Hao
Shen,Tie
Xie,Xiaoyao
dc.subject.por.fl_str_mv metabolic network
pan-metabolic network
metabolic network evolution
connected component
enzyme reaction
topic metabolic network
pan-metabolic network
metabolic network evolution
connected component
enzyme reaction
description Abstract The evolution of species is inevitably accompanied by the evolution of metabolic networks to adapt to different environments. The metabolic networks of different species were collected from the Kyoto Encyclopedia of Genes and Genomes (KEGG) website, and some enzyme reactions with the highest occurrence frequency in all species were found and are reported in this paper. The correlation coefficients of whether the enzyme reactions appear in all species were calculated, and the corresponding evolutionary correlation connection networks were calculated according to different correlation coefficient thresholds. These studies show that, as the evolutionary correlation of enzyme reactions increases, the weighted average of the mean functional concentration ratios of the enzyme reactions also increases, indicating that the functional concentration ratio of enzyme reactions has a certain correlation with the evolutionary correlation. The work presented in this paper enhances our understanding of the characteristics and general rules of metabolic network evolution.
publishDate 2021
dc.date.none.fl_str_mv 2021-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132021000100605
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132021000100605
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-4324-2021190480
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.64 2021
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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