The effects of low level laser therapy on injured skeletal muscle

Detalhes bibliográficos
Autor(a) principal: Renno,Ana Claudia Muniz
Data de Publicação: 2014
Outros Autores: Assis,Lívia, Peres,Beatriz, Rodrigues,Natalia Camargo, Brunelli,Roberta de Matos, Toma,Renata Luri, Medalha,Carla Christina, Ribeiro,Daniel Araki
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000100008
Resumo: The main purpose of the present study was to investigate the effects of low-level laser therapy (LLLT) used in two different fluencies on injured skeletal muscle after cryolesion by means of histopathological analysis and immunohistochemistry for COX-2. A total of sixty male Wistar rats were randomly distributed into three groups: injured animals without any treatment; 808 nm laser treated group, at 10 J/cm² and 808 nm laser treated group, at 50 J/cm². Each group was divided into two different subgroups (n=10) on days 6 and 13 post-injury. The results showed that the animals irradiated with laser at 10 J/cm² or 50 J/cm² presented the areas with cell infiltrate and pointed out to minor and mild areas with destroyed zones compared with the control group. Also, a COX-2 downregulation was noticed in the groups exposed to laser at two fluences evaluated in this study. Significant statistically differences (p<0.05) were noticed to collagen deposition in the laser treated animals, with the fluence of 50 J/cm² when compared to the other groups on day 13 post-surgery. Taken together, these results suggested that laser therapy could have positive effects on muscle repair in the rats after cryolesion.
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spelling The effects of low level laser therapy on injured skeletal musclelow level laser therapyratmuscle repairCOX-2The main purpose of the present study was to investigate the effects of low-level laser therapy (LLLT) used in two different fluencies on injured skeletal muscle after cryolesion by means of histopathological analysis and immunohistochemistry for COX-2. A total of sixty male Wistar rats were randomly distributed into three groups: injured animals without any treatment; 808 nm laser treated group, at 10 J/cm² and 808 nm laser treated group, at 50 J/cm². Each group was divided into two different subgroups (n=10) on days 6 and 13 post-injury. The results showed that the animals irradiated with laser at 10 J/cm² or 50 J/cm² presented the areas with cell infiltrate and pointed out to minor and mild areas with destroyed zones compared with the control group. Also, a COX-2 downregulation was noticed in the groups exposed to laser at two fluences evaluated in this study. Significant statistically differences (p<0.05) were noticed to collagen deposition in the laser treated animals, with the fluence of 50 J/cm² when compared to the other groups on day 13 post-surgery. Taken together, these results suggested that laser therapy could have positive effects on muscle repair in the rats after cryolesion.Instituto de Tecnologia do Paraná - Tecpar2014-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000100008Brazilian Archives of Biology and Technology v.57 n.1 2014reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132014000100008info:eu-repo/semantics/openAccessRenno,Ana Claudia MunizAssis,LíviaPeres,BeatrizRodrigues,Natalia CamargoBrunelli,Roberta de MatosToma,Renata LuriMedalha,Carla ChristinaRibeiro,Daniel Arakieng2014-02-24T00:00:00Zoai:scielo:S1516-89132014000100008Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2014-02-24T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv The effects of low level laser therapy on injured skeletal muscle
title The effects of low level laser therapy on injured skeletal muscle
spellingShingle The effects of low level laser therapy on injured skeletal muscle
Renno,Ana Claudia Muniz
low level laser therapy
rat
muscle repair
COX-2
title_short The effects of low level laser therapy on injured skeletal muscle
title_full The effects of low level laser therapy on injured skeletal muscle
title_fullStr The effects of low level laser therapy on injured skeletal muscle
title_full_unstemmed The effects of low level laser therapy on injured skeletal muscle
title_sort The effects of low level laser therapy on injured skeletal muscle
author Renno,Ana Claudia Muniz
author_facet Renno,Ana Claudia Muniz
Assis,Lívia
Peres,Beatriz
Rodrigues,Natalia Camargo
Brunelli,Roberta de Matos
Toma,Renata Luri
Medalha,Carla Christina
Ribeiro,Daniel Araki
author_role author
author2 Assis,Lívia
Peres,Beatriz
Rodrigues,Natalia Camargo
Brunelli,Roberta de Matos
Toma,Renata Luri
Medalha,Carla Christina
Ribeiro,Daniel Araki
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Renno,Ana Claudia Muniz
Assis,Lívia
Peres,Beatriz
Rodrigues,Natalia Camargo
Brunelli,Roberta de Matos
Toma,Renata Luri
Medalha,Carla Christina
Ribeiro,Daniel Araki
dc.subject.por.fl_str_mv low level laser therapy
rat
muscle repair
COX-2
topic low level laser therapy
rat
muscle repair
COX-2
description The main purpose of the present study was to investigate the effects of low-level laser therapy (LLLT) used in two different fluencies on injured skeletal muscle after cryolesion by means of histopathological analysis and immunohistochemistry for COX-2. A total of sixty male Wistar rats were randomly distributed into three groups: injured animals without any treatment; 808 nm laser treated group, at 10 J/cm² and 808 nm laser treated group, at 50 J/cm². Each group was divided into two different subgroups (n=10) on days 6 and 13 post-injury. The results showed that the animals irradiated with laser at 10 J/cm² or 50 J/cm² presented the areas with cell infiltrate and pointed out to minor and mild areas with destroyed zones compared with the control group. Also, a COX-2 downregulation was noticed in the groups exposed to laser at two fluences evaluated in this study. Significant statistically differences (p<0.05) were noticed to collagen deposition in the laser treated animals, with the fluence of 50 J/cm² when compared to the other groups on day 13 post-surgery. Taken together, these results suggested that laser therapy could have positive effects on muscle repair in the rats after cryolesion.
publishDate 2014
dc.date.none.fl_str_mv 2014-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000100008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000100008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132014000100008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.57 n.1 2014
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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