Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake

Detalhes bibliográficos
Autor(a) principal: Cespedes,Isabel Cristina
Data de Publicação: 2018
Outros Autores: Assis,Livia, Thomaz,Rafael Moraes, Panfilio,Carlos Eduardo, Gonçalves,Luis, Muniz,Ana Claudia Renno
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100319
Resumo: ABSTRACT This study aimed to investigate the effects of low-level laser therapy (LLLT) on muscle repair in rats with chronic alcohol intake. Thirty male Wistar rats were distributed into three groups: injured tibialis anterior (TA) muscle without treatment (IC); chronic ingestion of alcohol plus injured TA muscle (AI); and chronic ingestion of alcohol plus injured TA plus LLLT (AIL). Each group was divided into two different subgroups, and rats were sacrificed on days 3 and 7 post-injury. Morphological features in the injured areas were similar with or without alcohol intake (IC and AI); however, LLLT promoted a decrease in the number of inflammatory cells and destroyed zones, as well as improved tissue organization (AIL). In general, alcohol intake caused a decrease in myogenic regulatory factors (MyoD and myogenin) and vascular endothelial growth factor in the AI group. Moreover, LLLT promoted recovery of these factors to the same level as in animals without alcohol intake (IC and AIL). LLLT was able to increase the expression of myogenic and vascular growth factors and stimulate skeletal muscle regeneration in rats with chronic alcohol intake.
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spelling Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol IntakeLow-level laser therapyalcohol intakemuscle repairABSTRACT This study aimed to investigate the effects of low-level laser therapy (LLLT) on muscle repair in rats with chronic alcohol intake. Thirty male Wistar rats were distributed into three groups: injured tibialis anterior (TA) muscle without treatment (IC); chronic ingestion of alcohol plus injured TA muscle (AI); and chronic ingestion of alcohol plus injured TA plus LLLT (AIL). Each group was divided into two different subgroups, and rats were sacrificed on days 3 and 7 post-injury. Morphological features in the injured areas were similar with or without alcohol intake (IC and AI); however, LLLT promoted a decrease in the number of inflammatory cells and destroyed zones, as well as improved tissue organization (AIL). In general, alcohol intake caused a decrease in myogenic regulatory factors (MyoD and myogenin) and vascular endothelial growth factor in the AI group. Moreover, LLLT promoted recovery of these factors to the same level as in animals without alcohol intake (IC and AIL). LLLT was able to increase the expression of myogenic and vascular growth factors and stimulate skeletal muscle regeneration in rats with chronic alcohol intake.Instituto de Tecnologia do Paraná - Tecpar2018-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100319Brazilian Archives of Biology and Technology v.61 2018reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/1678-4324-2018161223info:eu-repo/semantics/openAccessCespedes,Isabel CristinaAssis,LiviaThomaz,Rafael MoraesPanfilio,Carlos EduardoGonçalves,LuisMuniz,Ana Claudia Rennoeng2018-11-09T00:00:00Zoai:scielo:S1516-89132018000100319Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2018-11-09T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake
title Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake
spellingShingle Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake
Cespedes,Isabel Cristina
Low-level laser therapy
alcohol intake
muscle repair
title_short Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake
title_full Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake
title_fullStr Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake
title_full_unstemmed Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake
title_sort Effects of Low-level Laser Therapy on Muscle Repair in Rats with Chronic Alcohol Intake
author Cespedes,Isabel Cristina
author_facet Cespedes,Isabel Cristina
Assis,Livia
Thomaz,Rafael Moraes
Panfilio,Carlos Eduardo
Gonçalves,Luis
Muniz,Ana Claudia Renno
author_role author
author2 Assis,Livia
Thomaz,Rafael Moraes
Panfilio,Carlos Eduardo
Gonçalves,Luis
Muniz,Ana Claudia Renno
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Cespedes,Isabel Cristina
Assis,Livia
Thomaz,Rafael Moraes
Panfilio,Carlos Eduardo
Gonçalves,Luis
Muniz,Ana Claudia Renno
dc.subject.por.fl_str_mv Low-level laser therapy
alcohol intake
muscle repair
topic Low-level laser therapy
alcohol intake
muscle repair
description ABSTRACT This study aimed to investigate the effects of low-level laser therapy (LLLT) on muscle repair in rats with chronic alcohol intake. Thirty male Wistar rats were distributed into three groups: injured tibialis anterior (TA) muscle without treatment (IC); chronic ingestion of alcohol plus injured TA muscle (AI); and chronic ingestion of alcohol plus injured TA plus LLLT (AIL). Each group was divided into two different subgroups, and rats were sacrificed on days 3 and 7 post-injury. Morphological features in the injured areas were similar with or without alcohol intake (IC and AI); however, LLLT promoted a decrease in the number of inflammatory cells and destroyed zones, as well as improved tissue organization (AIL). In general, alcohol intake caused a decrease in myogenic regulatory factors (MyoD and myogenin) and vascular endothelial growth factor in the AI group. Moreover, LLLT promoted recovery of these factors to the same level as in animals without alcohol intake (IC and AIL). LLLT was able to increase the expression of myogenic and vascular growth factors and stimulate skeletal muscle regeneration in rats with chronic alcohol intake.
publishDate 2018
dc.date.none.fl_str_mv 2018-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100319
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100319
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-4324-2018161223
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.61 2018
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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