Radiolabelled cytokines for imaging chronic inflammation

Detalhes bibliográficos
Autor(a) principal: Signore,Alberto
Data de Publicação: 2002
Outros Autores: D'Alessandria,Calogero, Annovazzi,Alessio, Scopinaro,Francesco
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132002000500004
Resumo: Diagnosis and particularly follow-up of chronic inflammatory disorders could be often difficult in clinical practice. Indeed, traditional radiological techniques reveal only structural tissue alterations and are not able to monitor functional changes occurring in tissues affected by chronic inflammation. The continuous advances in the knowledge of the pathophysioloy of chronic disorders, combined with the progress of radiochemistry, led to the development of new specific radiolabelled agents for the imaging of chronic diseases. In this scenario, cytokines, due to their pivotal role in such diseases, represent good candidates as radiopharmaceuticals.
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spelling Radiolabelled cytokines for imaging chronic inflammationRadiolabelled cytokineschronic inflammationimagingDiagnosis and particularly follow-up of chronic inflammatory disorders could be often difficult in clinical practice. Indeed, traditional radiological techniques reveal only structural tissue alterations and are not able to monitor functional changes occurring in tissues affected by chronic inflammation. The continuous advances in the knowledge of the pathophysioloy of chronic disorders, combined with the progress of radiochemistry, led to the development of new specific radiolabelled agents for the imaging of chronic diseases. In this scenario, cytokines, due to their pivotal role in such diseases, represent good candidates as radiopharmaceuticals.Instituto de Tecnologia do Paraná - Tecpar2002-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132002000500004Brazilian Archives of Biology and Technology v.45 n.spe 2002reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132002000500004info:eu-repo/semantics/openAccessSignore,AlbertoD'Alessandria,CalogeroAnnovazzi,AlessioScopinaro,Francescoeng2002-10-18T00:00:00Zoai:scielo:S1516-89132002000500004Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2002-10-18T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Radiolabelled cytokines for imaging chronic inflammation
title Radiolabelled cytokines for imaging chronic inflammation
spellingShingle Radiolabelled cytokines for imaging chronic inflammation
Signore,Alberto
Radiolabelled cytokines
chronic inflammation
imaging
title_short Radiolabelled cytokines for imaging chronic inflammation
title_full Radiolabelled cytokines for imaging chronic inflammation
title_fullStr Radiolabelled cytokines for imaging chronic inflammation
title_full_unstemmed Radiolabelled cytokines for imaging chronic inflammation
title_sort Radiolabelled cytokines for imaging chronic inflammation
author Signore,Alberto
author_facet Signore,Alberto
D'Alessandria,Calogero
Annovazzi,Alessio
Scopinaro,Francesco
author_role author
author2 D'Alessandria,Calogero
Annovazzi,Alessio
Scopinaro,Francesco
author2_role author
author
author
dc.contributor.author.fl_str_mv Signore,Alberto
D'Alessandria,Calogero
Annovazzi,Alessio
Scopinaro,Francesco
dc.subject.por.fl_str_mv Radiolabelled cytokines
chronic inflammation
imaging
topic Radiolabelled cytokines
chronic inflammation
imaging
description Diagnosis and particularly follow-up of chronic inflammatory disorders could be often difficult in clinical practice. Indeed, traditional radiological techniques reveal only structural tissue alterations and are not able to monitor functional changes occurring in tissues affected by chronic inflammation. The continuous advances in the knowledge of the pathophysioloy of chronic disorders, combined with the progress of radiochemistry, led to the development of new specific radiolabelled agents for the imaging of chronic diseases. In this scenario, cytokines, due to their pivotal role in such diseases, represent good candidates as radiopharmaceuticals.
publishDate 2002
dc.date.none.fl_str_mv 2002-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132002000500004
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132002000500004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132002000500004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.45 n.spe 2002
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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