Radiopharmaceuticals for imaging chronic lymphocytic inflammation

Detalhes bibliográficos
Autor(a) principal: Malviya,Gaurav
Data de Publicação: 2007
Outros Autores: Vries,Erik F.J. de, Dierckx,Rudi A., Signore,Alberto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600002
Resumo: In the last few decades, a number of radiopharmaceuticals for imaging inflammation have been proposed that differ in their specificity and mechanism of uptake in inflamed foci as compared to the traditional inflammation imaging agents. Radiolabelled cytokines represent a reliable tool for the preclinical diagnosis of chronic inflammatory processes, even before anatomical and functional changes occur in affected tissues. Moreover, the introduction of radiolabelled monoclonal antibodies and sophisticated technique like PET/CT now make the field of inflammation imaging highly specific and accurate. In this review, different approaches of the established and experimental radiopharmaceuticals for imaging of chronic inflammation are discussed.
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spelling Radiopharmaceuticals for imaging chronic lymphocytic inflammationRadiopharmaceuticalsInflammationMolecular ImagingIn the last few decades, a number of radiopharmaceuticals for imaging inflammation have been proposed that differ in their specificity and mechanism of uptake in inflamed foci as compared to the traditional inflammation imaging agents. Radiolabelled cytokines represent a reliable tool for the preclinical diagnosis of chronic inflammatory processes, even before anatomical and functional changes occur in affected tissues. Moreover, the introduction of radiolabelled monoclonal antibodies and sophisticated technique like PET/CT now make the field of inflammation imaging highly specific and accurate. In this review, different approaches of the established and experimental radiopharmaceuticals for imaging of chronic inflammation are discussed.Instituto de Tecnologia do Paraná - Tecpar2007-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600002Brazilian Archives of Biology and Technology v.50 n.spe 2007reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132007000600002info:eu-repo/semantics/openAccessMalviya,GauravVries,Erik F.J. deDierckx,Rudi A.Signore,Albertoeng2008-03-12T00:00:00Zoai:scielo:S1516-89132007000600002Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2008-03-12T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Radiopharmaceuticals for imaging chronic lymphocytic inflammation
title Radiopharmaceuticals for imaging chronic lymphocytic inflammation
spellingShingle Radiopharmaceuticals for imaging chronic lymphocytic inflammation
Malviya,Gaurav
Radiopharmaceuticals
Inflammation
Molecular Imaging
title_short Radiopharmaceuticals for imaging chronic lymphocytic inflammation
title_full Radiopharmaceuticals for imaging chronic lymphocytic inflammation
title_fullStr Radiopharmaceuticals for imaging chronic lymphocytic inflammation
title_full_unstemmed Radiopharmaceuticals for imaging chronic lymphocytic inflammation
title_sort Radiopharmaceuticals for imaging chronic lymphocytic inflammation
author Malviya,Gaurav
author_facet Malviya,Gaurav
Vries,Erik F.J. de
Dierckx,Rudi A.
Signore,Alberto
author_role author
author2 Vries,Erik F.J. de
Dierckx,Rudi A.
Signore,Alberto
author2_role author
author
author
dc.contributor.author.fl_str_mv Malviya,Gaurav
Vries,Erik F.J. de
Dierckx,Rudi A.
Signore,Alberto
dc.subject.por.fl_str_mv Radiopharmaceuticals
Inflammation
Molecular Imaging
topic Radiopharmaceuticals
Inflammation
Molecular Imaging
description In the last few decades, a number of radiopharmaceuticals for imaging inflammation have been proposed that differ in their specificity and mechanism of uptake in inflamed foci as compared to the traditional inflammation imaging agents. Radiolabelled cytokines represent a reliable tool for the preclinical diagnosis of chronic inflammatory processes, even before anatomical and functional changes occur in affected tissues. Moreover, the introduction of radiolabelled monoclonal antibodies and sophisticated technique like PET/CT now make the field of inflammation imaging highly specific and accurate. In this review, different approaches of the established and experimental radiopharmaceuticals for imaging of chronic inflammation are discussed.
publishDate 2007
dc.date.none.fl_str_mv 2007-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132007000600002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.50 n.spe 2007
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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