Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review

Detalhes bibliográficos
Autor(a) principal: Gamba,Luize Kremer
Data de Publicação: 2023
Outros Autores: Ribeiro,Victoria Stadler Tasca, Simeoni,Rossana Baggio, Gamba,Laiza Kremer, Graf,Elis Cristine Bevian, Denk,Marcos Antônio, Almeida,Meila Bastos de, Simeoni,Paulo Ricardo Baggio, Barbosa,Carlos de Almeida, Francisco,Julio Cesar, Guarita-Souza,Luiz Cesar
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000100303
Resumo: Abstract The use of Wharton's Jelly (WJ) as a biomaterial is currently undergoing an appearance in the regenerative medicine field. The biomaterials applications focus on the aspects of cellular growth or delivery of proteins capable of stimulating cellular response. However, the basic knowledge about Wharton jelly and decellularization processing technology combined with understanding the physical-chemical properties of this biomaterial is necessary for proper application in regenerative medicine. This mini-review article summarizes information on the composition of WJ, application of drug delivery, in medicine and discusses recent developments with a special focus on its use for regenerative medicine. The most successful and stimulating applications are studies in regenerative medicine and tissue engineering, for wound healing to treat burns, tumor treatment, nanoparticle carriers, and drug delivery systems.
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spelling Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Reviewcell seedingdecellularized Wharton's jelly matrixnatural scaffoldstissue decellularizationWharton's jelly matrix.Abstract The use of Wharton's Jelly (WJ) as a biomaterial is currently undergoing an appearance in the regenerative medicine field. The biomaterials applications focus on the aspects of cellular growth or delivery of proteins capable of stimulating cellular response. However, the basic knowledge about Wharton jelly and decellularization processing technology combined with understanding the physical-chemical properties of this biomaterial is necessary for proper application in regenerative medicine. This mini-review article summarizes information on the composition of WJ, application of drug delivery, in medicine and discusses recent developments with a special focus on its use for regenerative medicine. The most successful and stimulating applications are studies in regenerative medicine and tissue engineering, for wound healing to treat burns, tumor treatment, nanoparticle carriers, and drug delivery systems.Instituto de Tecnologia do Paraná - Tecpar2023-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000100303Brazilian Archives of Biology and Technology v.66 2023reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/1678-4324-2023220292info:eu-repo/semantics/openAccessGamba,Luize KremerRibeiro,Victoria Stadler TascaSimeoni,Rossana BaggioGamba,Laiza KremerGraf,Elis Cristine BevianDenk,Marcos AntônioAlmeida,Meila Bastos deSimeoni,Paulo Ricardo BaggioBarbosa,Carlos de AlmeidaFrancisco,Julio CesarGuarita-Souza,Luiz Cesareng2022-09-13T00:00:00Zoai:scielo:S1516-89132023000100303Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2022-09-13T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review
title Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review
spellingShingle Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review
Gamba,Luize Kremer
cell seeding
decellularized Wharton's jelly matrix
natural scaffolds
tissue decellularization
Wharton's jelly matrix.
title_short Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review
title_full Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review
title_fullStr Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review
title_full_unstemmed Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review
title_sort Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review
author Gamba,Luize Kremer
author_facet Gamba,Luize Kremer
Ribeiro,Victoria Stadler Tasca
Simeoni,Rossana Baggio
Gamba,Laiza Kremer
Graf,Elis Cristine Bevian
Denk,Marcos Antônio
Almeida,Meila Bastos de
Simeoni,Paulo Ricardo Baggio
Barbosa,Carlos de Almeida
Francisco,Julio Cesar
Guarita-Souza,Luiz Cesar
author_role author
author2 Ribeiro,Victoria Stadler Tasca
Simeoni,Rossana Baggio
Gamba,Laiza Kremer
Graf,Elis Cristine Bevian
Denk,Marcos Antônio
Almeida,Meila Bastos de
Simeoni,Paulo Ricardo Baggio
Barbosa,Carlos de Almeida
Francisco,Julio Cesar
Guarita-Souza,Luiz Cesar
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gamba,Luize Kremer
Ribeiro,Victoria Stadler Tasca
Simeoni,Rossana Baggio
Gamba,Laiza Kremer
Graf,Elis Cristine Bevian
Denk,Marcos Antônio
Almeida,Meila Bastos de
Simeoni,Paulo Ricardo Baggio
Barbosa,Carlos de Almeida
Francisco,Julio Cesar
Guarita-Souza,Luiz Cesar
dc.subject.por.fl_str_mv cell seeding
decellularized Wharton's jelly matrix
natural scaffolds
tissue decellularization
Wharton's jelly matrix.
topic cell seeding
decellularized Wharton's jelly matrix
natural scaffolds
tissue decellularization
Wharton's jelly matrix.
description Abstract The use of Wharton's Jelly (WJ) as a biomaterial is currently undergoing an appearance in the regenerative medicine field. The biomaterials applications focus on the aspects of cellular growth or delivery of proteins capable of stimulating cellular response. However, the basic knowledge about Wharton jelly and decellularization processing technology combined with understanding the physical-chemical properties of this biomaterial is necessary for proper application in regenerative medicine. This mini-review article summarizes information on the composition of WJ, application of drug delivery, in medicine and discusses recent developments with a special focus on its use for regenerative medicine. The most successful and stimulating applications are studies in regenerative medicine and tissue engineering, for wound healing to treat burns, tumor treatment, nanoparticle carriers, and drug delivery systems.
publishDate 2023
dc.date.none.fl_str_mv 2023-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000100303
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000100303
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-4324-2023220292
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.66 2023
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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