Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Archives of Biology and Technology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000100303 |
Resumo: | Abstract The use of Wharton's Jelly (WJ) as a biomaterial is currently undergoing an appearance in the regenerative medicine field. The biomaterials applications focus on the aspects of cellular growth or delivery of proteins capable of stimulating cellular response. However, the basic knowledge about Wharton jelly and decellularization processing technology combined with understanding the physical-chemical properties of this biomaterial is necessary for proper application in regenerative medicine. This mini-review article summarizes information on the composition of WJ, application of drug delivery, in medicine and discusses recent developments with a special focus on its use for regenerative medicine. The most successful and stimulating applications are studies in regenerative medicine and tissue engineering, for wound healing to treat burns, tumor treatment, nanoparticle carriers, and drug delivery systems. |
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Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Reviewcell seedingdecellularized Wharton's jelly matrixnatural scaffoldstissue decellularizationWharton's jelly matrix.Abstract The use of Wharton's Jelly (WJ) as a biomaterial is currently undergoing an appearance in the regenerative medicine field. The biomaterials applications focus on the aspects of cellular growth or delivery of proteins capable of stimulating cellular response. However, the basic knowledge about Wharton jelly and decellularization processing technology combined with understanding the physical-chemical properties of this biomaterial is necessary for proper application in regenerative medicine. This mini-review article summarizes information on the composition of WJ, application of drug delivery, in medicine and discusses recent developments with a special focus on its use for regenerative medicine. The most successful and stimulating applications are studies in regenerative medicine and tissue engineering, for wound healing to treat burns, tumor treatment, nanoparticle carriers, and drug delivery systems.Instituto de Tecnologia do Paraná - Tecpar2023-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000100303Brazilian Archives of Biology and Technology v.66 2023reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/1678-4324-2023220292info:eu-repo/semantics/openAccessGamba,Luize KremerRibeiro,Victoria Stadler TascaSimeoni,Rossana BaggioGamba,Laiza KremerGraf,Elis Cristine BevianDenk,Marcos AntônioAlmeida,Meila Bastos deSimeoni,Paulo Ricardo BaggioBarbosa,Carlos de AlmeidaFrancisco,Julio CesarGuarita-Souza,Luiz Cesareng2022-09-13T00:00:00Zoai:scielo:S1516-89132023000100303Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2022-09-13T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false |
dc.title.none.fl_str_mv |
Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review |
title |
Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review |
spellingShingle |
Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review Gamba,Luize Kremer cell seeding decellularized Wharton's jelly matrix natural scaffolds tissue decellularization Wharton's jelly matrix. |
title_short |
Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review |
title_full |
Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review |
title_fullStr |
Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review |
title_full_unstemmed |
Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review |
title_sort |
Decellularized Wharton’s Jelly: Biomaterial Potential for Regenerative Medicine Applications - A Mini-Review |
author |
Gamba,Luize Kremer |
author_facet |
Gamba,Luize Kremer Ribeiro,Victoria Stadler Tasca Simeoni,Rossana Baggio Gamba,Laiza Kremer Graf,Elis Cristine Bevian Denk,Marcos Antônio Almeida,Meila Bastos de Simeoni,Paulo Ricardo Baggio Barbosa,Carlos de Almeida Francisco,Julio Cesar Guarita-Souza,Luiz Cesar |
author_role |
author |
author2 |
Ribeiro,Victoria Stadler Tasca Simeoni,Rossana Baggio Gamba,Laiza Kremer Graf,Elis Cristine Bevian Denk,Marcos Antônio Almeida,Meila Bastos de Simeoni,Paulo Ricardo Baggio Barbosa,Carlos de Almeida Francisco,Julio Cesar Guarita-Souza,Luiz Cesar |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Gamba,Luize Kremer Ribeiro,Victoria Stadler Tasca Simeoni,Rossana Baggio Gamba,Laiza Kremer Graf,Elis Cristine Bevian Denk,Marcos Antônio Almeida,Meila Bastos de Simeoni,Paulo Ricardo Baggio Barbosa,Carlos de Almeida Francisco,Julio Cesar Guarita-Souza,Luiz Cesar |
dc.subject.por.fl_str_mv |
cell seeding decellularized Wharton's jelly matrix natural scaffolds tissue decellularization Wharton's jelly matrix. |
topic |
cell seeding decellularized Wharton's jelly matrix natural scaffolds tissue decellularization Wharton's jelly matrix. |
description |
Abstract The use of Wharton's Jelly (WJ) as a biomaterial is currently undergoing an appearance in the regenerative medicine field. The biomaterials applications focus on the aspects of cellular growth or delivery of proteins capable of stimulating cellular response. However, the basic knowledge about Wharton jelly and decellularization processing technology combined with understanding the physical-chemical properties of this biomaterial is necessary for proper application in regenerative medicine. This mini-review article summarizes information on the composition of WJ, application of drug delivery, in medicine and discusses recent developments with a special focus on its use for regenerative medicine. The most successful and stimulating applications are studies in regenerative medicine and tissue engineering, for wound healing to treat burns, tumor treatment, nanoparticle carriers, and drug delivery systems. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000100303 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000100303 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1678-4324-2023220292 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
dc.source.none.fl_str_mv |
Brazilian Archives of Biology and Technology v.66 2023 reponame:Brazilian Archives of Biology and Technology instname:Instituto de Tecnologia do Paraná (Tecpar) instacron:TECPAR |
instname_str |
Instituto de Tecnologia do Paraná (Tecpar) |
instacron_str |
TECPAR |
institution |
TECPAR |
reponame_str |
Brazilian Archives of Biology and Technology |
collection |
Brazilian Archives of Biology and Technology |
repository.name.fl_str_mv |
Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar) |
repository.mail.fl_str_mv |
babt@tecpar.br||babt@tecpar.br |
_version_ |
1750318281726623744 |