Thermodynamics of molecular recognitions between antineoplastic drug taxol and phosphatidylcholine

Detalhes bibliográficos
Autor(a) principal: Süleymanoglu,Erhan
Data de Publicação: 2010
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000600011
Resumo: The aim of this study was to study the basic features of Taxol recognition with phospholipids by applying the thermodynamic and spectroscopic measurements. The obtained information could be used further for deductions on its precise cellular and pharmacological mechanisms of action, on improvements of its solubility properties by phospholipids, as well as for designing the novel lipidic carriers for drug delivery.
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spelling Thermodynamics of molecular recognitions between antineoplastic drug taxol and phosphatidylcholineAntineoplastic agentschemotherapyTaxolphoshatidylcholineTaxol-membrane interactionsmembrane fluidityThe aim of this study was to study the basic features of Taxol recognition with phospholipids by applying the thermodynamic and spectroscopic measurements. The obtained information could be used further for deductions on its precise cellular and pharmacological mechanisms of action, on improvements of its solubility properties by phospholipids, as well as for designing the novel lipidic carriers for drug delivery.Instituto de Tecnologia do Paraná - Tecpar2010-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000600011Brazilian Archives of Biology and Technology v.53 n.6 2010reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132010000600011info:eu-repo/semantics/openAccessSüleymanoglu,Erhaneng2011-01-18T00:00:00Zoai:scielo:S1516-89132010000600011Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2011-01-18T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Thermodynamics of molecular recognitions between antineoplastic drug taxol and phosphatidylcholine
title Thermodynamics of molecular recognitions between antineoplastic drug taxol and phosphatidylcholine
spellingShingle Thermodynamics of molecular recognitions between antineoplastic drug taxol and phosphatidylcholine
Süleymanoglu,Erhan
Antineoplastic agents
chemotherapy
Taxol
phoshatidylcholine
Taxol-membrane interactions
membrane fluidity
title_short Thermodynamics of molecular recognitions between antineoplastic drug taxol and phosphatidylcholine
title_full Thermodynamics of molecular recognitions between antineoplastic drug taxol and phosphatidylcholine
title_fullStr Thermodynamics of molecular recognitions between antineoplastic drug taxol and phosphatidylcholine
title_full_unstemmed Thermodynamics of molecular recognitions between antineoplastic drug taxol and phosphatidylcholine
title_sort Thermodynamics of molecular recognitions between antineoplastic drug taxol and phosphatidylcholine
author Süleymanoglu,Erhan
author_facet Süleymanoglu,Erhan
author_role author
dc.contributor.author.fl_str_mv Süleymanoglu,Erhan
dc.subject.por.fl_str_mv Antineoplastic agents
chemotherapy
Taxol
phoshatidylcholine
Taxol-membrane interactions
membrane fluidity
topic Antineoplastic agents
chemotherapy
Taxol
phoshatidylcholine
Taxol-membrane interactions
membrane fluidity
description The aim of this study was to study the basic features of Taxol recognition with phospholipids by applying the thermodynamic and spectroscopic measurements. The obtained information could be used further for deductions on its precise cellular and pharmacological mechanisms of action, on improvements of its solubility properties by phospholipids, as well as for designing the novel lipidic carriers for drug delivery.
publishDate 2010
dc.date.none.fl_str_mv 2010-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000600011
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000600011
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132010000600011
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.53 n.6 2010
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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