Comparison of chemical constituents of Chamomilla recutita (L.) rauschert essential oil and its anti-chemotactic activity
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Archives of Biology and Technology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000600005 |
Resumo: | Several essential oil samples from dried flower-heads of Chamomilla recutita (L.) Rauschert, grown and commercially available around Curitiba metropolitan area, South of Brazil, were analyzed by GC-MS and the chemical constituents were compared with an Egyptian sample obtained under similar conditions and used as a control. The local grown herbs showed levels of essential oil below the standards recommended by the Brazilian Pharmacopoeia. Also, differences in their composition as well as in the quantity of several components were found such as the unexpected inversion of the relative constitution of the A and B alpha-bisabolol oxides. Of particular interest was the striking effect of the chamomile extracts upon human leukocyte chemotaxis, a biological anti-inflammatory activity not reported before, in which cell migration was in vitro inhibited at the same level as showed by dexamethasone. |
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Comparison of chemical constituents of Chamomilla recutita (L.) rauschert essential oil and its anti-chemotactic activityChamomilla recutitaAsteraceaeessential oilchemotaxisbisabolol oxideSeveral essential oil samples from dried flower-heads of Chamomilla recutita (L.) Rauschert, grown and commercially available around Curitiba metropolitan area, South of Brazil, were analyzed by GC-MS and the chemical constituents were compared with an Egyptian sample obtained under similar conditions and used as a control. The local grown herbs showed levels of essential oil below the standards recommended by the Brazilian Pharmacopoeia. Also, differences in their composition as well as in the quantity of several components were found such as the unexpected inversion of the relative constitution of the A and B alpha-bisabolol oxides. Of particular interest was the striking effect of the chamomile extracts upon human leukocyte chemotaxis, a biological anti-inflammatory activity not reported before, in which cell migration was in vitro inhibited at the same level as showed by dexamethasone.Instituto de Tecnologia do Paraná - Tecpar2006-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000600005Brazilian Archives of Biology and Technology v.49 n.5 2006reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132006000600005info:eu-repo/semantics/openAccessPresibella,Mayra MarinhoVillas-Bôas,Larissa De BiaggiBelletti,Klézia Morais da SilvaSantos,Cid Aimbiré de MoraesWeffort-Santos,Almeriane Mariaeng2007-02-26T00:00:00Zoai:scielo:S1516-89132006000600005Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2007-02-26T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false |
dc.title.none.fl_str_mv |
Comparison of chemical constituents of Chamomilla recutita (L.) rauschert essential oil and its anti-chemotactic activity |
title |
Comparison of chemical constituents of Chamomilla recutita (L.) rauschert essential oil and its anti-chemotactic activity |
spellingShingle |
Comparison of chemical constituents of Chamomilla recutita (L.) rauschert essential oil and its anti-chemotactic activity Presibella,Mayra Marinho Chamomilla recutita Asteraceae essential oil chemotaxis bisabolol oxide |
title_short |
Comparison of chemical constituents of Chamomilla recutita (L.) rauschert essential oil and its anti-chemotactic activity |
title_full |
Comparison of chemical constituents of Chamomilla recutita (L.) rauschert essential oil and its anti-chemotactic activity |
title_fullStr |
Comparison of chemical constituents of Chamomilla recutita (L.) rauschert essential oil and its anti-chemotactic activity |
title_full_unstemmed |
Comparison of chemical constituents of Chamomilla recutita (L.) rauschert essential oil and its anti-chemotactic activity |
title_sort |
Comparison of chemical constituents of Chamomilla recutita (L.) rauschert essential oil and its anti-chemotactic activity |
author |
Presibella,Mayra Marinho |
author_facet |
Presibella,Mayra Marinho Villas-Bôas,Larissa De Biaggi Belletti,Klézia Morais da Silva Santos,Cid Aimbiré de Moraes Weffort-Santos,Almeriane Maria |
author_role |
author |
author2 |
Villas-Bôas,Larissa De Biaggi Belletti,Klézia Morais da Silva Santos,Cid Aimbiré de Moraes Weffort-Santos,Almeriane Maria |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Presibella,Mayra Marinho Villas-Bôas,Larissa De Biaggi Belletti,Klézia Morais da Silva Santos,Cid Aimbiré de Moraes Weffort-Santos,Almeriane Maria |
dc.subject.por.fl_str_mv |
Chamomilla recutita Asteraceae essential oil chemotaxis bisabolol oxide |
topic |
Chamomilla recutita Asteraceae essential oil chemotaxis bisabolol oxide |
description |
Several essential oil samples from dried flower-heads of Chamomilla recutita (L.) Rauschert, grown and commercially available around Curitiba metropolitan area, South of Brazil, were analyzed by GC-MS and the chemical constituents were compared with an Egyptian sample obtained under similar conditions and used as a control. The local grown herbs showed levels of essential oil below the standards recommended by the Brazilian Pharmacopoeia. Also, differences in their composition as well as in the quantity of several components were found such as the unexpected inversion of the relative constitution of the A and B alpha-bisabolol oxides. Of particular interest was the striking effect of the chamomile extracts upon human leukocyte chemotaxis, a biological anti-inflammatory activity not reported before, in which cell migration was in vitro inhibited at the same level as showed by dexamethasone. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000600005 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000600005 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1516-89132006000600005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
dc.source.none.fl_str_mv |
Brazilian Archives of Biology and Technology v.49 n.5 2006 reponame:Brazilian Archives of Biology and Technology instname:Instituto de Tecnologia do Paraná (Tecpar) instacron:TECPAR |
instname_str |
Instituto de Tecnologia do Paraná (Tecpar) |
instacron_str |
TECPAR |
institution |
TECPAR |
reponame_str |
Brazilian Archives of Biology and Technology |
collection |
Brazilian Archives of Biology and Technology |
repository.name.fl_str_mv |
Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar) |
repository.mail.fl_str_mv |
babt@tecpar.br||babt@tecpar.br |
_version_ |
1750318271127617536 |