Effects of Endurance Training with or without Rosehip Fruits (Rosa canina L) Extraction and D-galactose Solution on Plasmatic Liver Enzymes, Lipid Profiles, Selected Biochemical Variables in Male Rats
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Archives of Biology and Technology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132022000100420 |
Resumo: | Abstract The aims of the present study were to examine the effects of D-galactose (DG) supplementation on plasma aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), creatinine, albumin, urea, bilirubin, cholesterol, and triglyceride. We also investigated the effects of Rosehip (Rosa canina L) fruit extraction and endurance exercise training on DG-induced changes in the aforementioned variables in male rats. Eighty-six male rats were randomly assigned to 8 groups 1) Control Saline 2) Training Saline 3) Control D-galactose 4) Training D-galactose 5) Control Rosehip 6) Training Rosehip 7) Control combined group and 8) Training combined group. Animals received experiments on the base of groups’ names (eight weeks and five times per week). Seventy-two hours after the last training or control session plasma was collected. The results showed that endurance training significantly increased plasma albumin while reducing ALT and creatinine. Rosehip significantly reduced plasma AST, creatinine, urea, cholesterol, and triglyceride, and increased bilirubin. A combination of training and Rosehip causes an additive effect compared to each intervention alone on AST. The use of DG increased ALT, AST, ALP, creatinine, urea, bilirubin, cholesterol, and triglyceride, while decreasing albumin. The use of Rosehip in combination with DG was able to minimize DG-induced abnormal elevation on some variables. In conclusion, using a high dose of D-galactose solution or high galactose content foods could make a precondition background for the non-alcoholic fatty liver which could be attenuated by crud Rosehip extraction. Thus, it seems that the Rosehip can be considered a hepatoprotective herb. |
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Brazilian Archives of Biology and Technology |
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Effects of Endurance Training with or without Rosehip Fruits (Rosa canina L) Extraction and D-galactose Solution on Plasmatic Liver Enzymes, Lipid Profiles, Selected Biochemical Variables in Male RatsAlbuminaminotransferase (AST)bilirubincholesterolcreatinineurea.Abstract The aims of the present study were to examine the effects of D-galactose (DG) supplementation on plasma aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), creatinine, albumin, urea, bilirubin, cholesterol, and triglyceride. We also investigated the effects of Rosehip (Rosa canina L) fruit extraction and endurance exercise training on DG-induced changes in the aforementioned variables in male rats. Eighty-six male rats were randomly assigned to 8 groups 1) Control Saline 2) Training Saline 3) Control D-galactose 4) Training D-galactose 5) Control Rosehip 6) Training Rosehip 7) Control combined group and 8) Training combined group. Animals received experiments on the base of groups’ names (eight weeks and five times per week). Seventy-two hours after the last training or control session plasma was collected. The results showed that endurance training significantly increased plasma albumin while reducing ALT and creatinine. Rosehip significantly reduced plasma AST, creatinine, urea, cholesterol, and triglyceride, and increased bilirubin. A combination of training and Rosehip causes an additive effect compared to each intervention alone on AST. The use of DG increased ALT, AST, ALP, creatinine, urea, bilirubin, cholesterol, and triglyceride, while decreasing albumin. The use of Rosehip in combination with DG was able to minimize DG-induced abnormal elevation on some variables. In conclusion, using a high dose of D-galactose solution or high galactose content foods could make a precondition background for the non-alcoholic fatty liver which could be attenuated by crud Rosehip extraction. Thus, it seems that the Rosehip can be considered a hepatoprotective herb.Instituto de Tecnologia do Paraná - Tecpar2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132022000100420Brazilian Archives of Biology and Technology v.65 2022reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/1678-4324-2022210460info:eu-repo/semantics/openAccessGhanbari-Niaki,AbbassRahmati-Ahmadabad,SalehBroom,David RobertKolbadinejad,Ali-AkbarNikbakht,JamalHofmeister,Martineng2022-10-21T00:00:00Zoai:scielo:S1516-89132022000100420Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2022-10-21T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false |
dc.title.none.fl_str_mv |
Effects of Endurance Training with or without Rosehip Fruits (Rosa canina L) Extraction and D-galactose Solution on Plasmatic Liver Enzymes, Lipid Profiles, Selected Biochemical Variables in Male Rats |
title |
Effects of Endurance Training with or without Rosehip Fruits (Rosa canina L) Extraction and D-galactose Solution on Plasmatic Liver Enzymes, Lipid Profiles, Selected Biochemical Variables in Male Rats |
spellingShingle |
Effects of Endurance Training with or without Rosehip Fruits (Rosa canina L) Extraction and D-galactose Solution on Plasmatic Liver Enzymes, Lipid Profiles, Selected Biochemical Variables in Male Rats Ghanbari-Niaki,Abbass Albumin aminotransferase (AST) bilirubin cholesterol creatinine urea. |
title_short |
Effects of Endurance Training with or without Rosehip Fruits (Rosa canina L) Extraction and D-galactose Solution on Plasmatic Liver Enzymes, Lipid Profiles, Selected Biochemical Variables in Male Rats |
title_full |
Effects of Endurance Training with or without Rosehip Fruits (Rosa canina L) Extraction and D-galactose Solution on Plasmatic Liver Enzymes, Lipid Profiles, Selected Biochemical Variables in Male Rats |
title_fullStr |
Effects of Endurance Training with or without Rosehip Fruits (Rosa canina L) Extraction and D-galactose Solution on Plasmatic Liver Enzymes, Lipid Profiles, Selected Biochemical Variables in Male Rats |
title_full_unstemmed |
Effects of Endurance Training with or without Rosehip Fruits (Rosa canina L) Extraction and D-galactose Solution on Plasmatic Liver Enzymes, Lipid Profiles, Selected Biochemical Variables in Male Rats |
title_sort |
Effects of Endurance Training with or without Rosehip Fruits (Rosa canina L) Extraction and D-galactose Solution on Plasmatic Liver Enzymes, Lipid Profiles, Selected Biochemical Variables in Male Rats |
author |
Ghanbari-Niaki,Abbass |
author_facet |
Ghanbari-Niaki,Abbass Rahmati-Ahmadabad,Saleh Broom,David Robert Kolbadinejad,Ali-Akbar Nikbakht,Jamal Hofmeister,Martin |
author_role |
author |
author2 |
Rahmati-Ahmadabad,Saleh Broom,David Robert Kolbadinejad,Ali-Akbar Nikbakht,Jamal Hofmeister,Martin |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Ghanbari-Niaki,Abbass Rahmati-Ahmadabad,Saleh Broom,David Robert Kolbadinejad,Ali-Akbar Nikbakht,Jamal Hofmeister,Martin |
dc.subject.por.fl_str_mv |
Albumin aminotransferase (AST) bilirubin cholesterol creatinine urea. |
topic |
Albumin aminotransferase (AST) bilirubin cholesterol creatinine urea. |
description |
Abstract The aims of the present study were to examine the effects of D-galactose (DG) supplementation on plasma aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), creatinine, albumin, urea, bilirubin, cholesterol, and triglyceride. We also investigated the effects of Rosehip (Rosa canina L) fruit extraction and endurance exercise training on DG-induced changes in the aforementioned variables in male rats. Eighty-six male rats were randomly assigned to 8 groups 1) Control Saline 2) Training Saline 3) Control D-galactose 4) Training D-galactose 5) Control Rosehip 6) Training Rosehip 7) Control combined group and 8) Training combined group. Animals received experiments on the base of groups’ names (eight weeks and five times per week). Seventy-two hours after the last training or control session plasma was collected. The results showed that endurance training significantly increased plasma albumin while reducing ALT and creatinine. Rosehip significantly reduced plasma AST, creatinine, urea, cholesterol, and triglyceride, and increased bilirubin. A combination of training and Rosehip causes an additive effect compared to each intervention alone on AST. The use of DG increased ALT, AST, ALP, creatinine, urea, bilirubin, cholesterol, and triglyceride, while decreasing albumin. The use of Rosehip in combination with DG was able to minimize DG-induced abnormal elevation on some variables. In conclusion, using a high dose of D-galactose solution or high galactose content foods could make a precondition background for the non-alcoholic fatty liver which could be attenuated by crud Rosehip extraction. Thus, it seems that the Rosehip can be considered a hepatoprotective herb. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132022000100420 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132022000100420 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1678-4324-2022210460 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
dc.source.none.fl_str_mv |
Brazilian Archives of Biology and Technology v.65 2022 reponame:Brazilian Archives of Biology and Technology instname:Instituto de Tecnologia do Paraná (Tecpar) instacron:TECPAR |
instname_str |
Instituto de Tecnologia do Paraná (Tecpar) |
instacron_str |
TECPAR |
institution |
TECPAR |
reponame_str |
Brazilian Archives of Biology and Technology |
collection |
Brazilian Archives of Biology and Technology |
repository.name.fl_str_mv |
Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar) |
repository.mail.fl_str_mv |
babt@tecpar.br||babt@tecpar.br |
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1750318281441411072 |