Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352012000600001 |
Resumo: | This study aimed to determine the power of the serum aspartate aminotransferase (AST) and gamma-glutamyltransferasase (GGT) activities and of the albumin and cholesterol dosages for detecting hepatic histopathological injuries. A total of 220 healthy male Nelore cattle that had been extensively bred were evaluated. Blood and liver samples were collected on the day of slaughter for biochemical and histopathological tests. The results showed that the sensitivity to AST, GGT, albumin, and cholesterol tests were respectively 22.4%, 22.4%, 36%, and 37.2%. The specificity of AST, GGT, albumin, and cholesterol tests was respectively 78.8%, 90.4%, 75.6%, and 68.3%. In short, the detection of minor liver injuries through biochemical tests is limited; however, the high specificity of the GGT allows its use as an indicator of hepatic chronic injuries in cattle herds. |
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Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
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Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signsbeef cattlealbuminASTcholesterolclinical biochemistryGGTThis study aimed to determine the power of the serum aspartate aminotransferase (AST) and gamma-glutamyltransferasase (GGT) activities and of the albumin and cholesterol dosages for detecting hepatic histopathological injuries. A total of 220 healthy male Nelore cattle that had been extensively bred were evaluated. Blood and liver samples were collected on the day of slaughter for biochemical and histopathological tests. The results showed that the sensitivity to AST, GGT, albumin, and cholesterol tests were respectively 22.4%, 22.4%, 36%, and 37.2%. The specificity of AST, GGT, albumin, and cholesterol tests was respectively 78.8%, 90.4%, 75.6%, and 68.3%. In short, the detection of minor liver injuries through biochemical tests is limited; however, the high specificity of the GGT allows its use as an indicator of hepatic chronic injuries in cattle herds.Universidade Federal de Minas Gerais, Escola de Veterinária2012-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352012000600001Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.64 n.6 2012reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)instname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG10.1590/S0102-09352012000600001info:eu-repo/semantics/openAccessMoreira,C.N.Souza,S.N.Barini,A.C.Araújo,E.G.Fioravanti,M.C.S.eng2013-01-10T00:00:00Zoai:scielo:S0102-09352012000600001Revistahttps://www.scielo.br/j/abmvz/PUBhttps://old.scielo.br/oai/scielo-oai.phpjournal@vet.ufmg.br||abmvz.artigo@abmvz.org.br1678-41620102-0935opendoar:2013-01-10T00:00Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)false |
dc.title.none.fl_str_mv |
Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs |
title |
Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs |
spellingShingle |
Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs Moreira,C.N. beef cattle albumin AST cholesterol clinical biochemistry GGT |
title_short |
Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs |
title_full |
Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs |
title_fullStr |
Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs |
title_full_unstemmed |
Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs |
title_sort |
Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs |
author |
Moreira,C.N. |
author_facet |
Moreira,C.N. Souza,S.N. Barini,A.C. Araújo,E.G. Fioravanti,M.C.S. |
author_role |
author |
author2 |
Souza,S.N. Barini,A.C. Araújo,E.G. Fioravanti,M.C.S. |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Moreira,C.N. Souza,S.N. Barini,A.C. Araújo,E.G. Fioravanti,M.C.S. |
dc.subject.por.fl_str_mv |
beef cattle albumin AST cholesterol clinical biochemistry GGT |
topic |
beef cattle albumin AST cholesterol clinical biochemistry GGT |
description |
This study aimed to determine the power of the serum aspartate aminotransferase (AST) and gamma-glutamyltransferasase (GGT) activities and of the albumin and cholesterol dosages for detecting hepatic histopathological injuries. A total of 220 healthy male Nelore cattle that had been extensively bred were evaluated. Blood and liver samples were collected on the day of slaughter for biochemical and histopathological tests. The results showed that the sensitivity to AST, GGT, albumin, and cholesterol tests were respectively 22.4%, 22.4%, 36%, and 37.2%. The specificity of AST, GGT, albumin, and cholesterol tests was respectively 78.8%, 90.4%, 75.6%, and 68.3%. In short, the detection of minor liver injuries through biochemical tests is limited; however, the high specificity of the GGT allows its use as an indicator of hepatic chronic injuries in cattle herds. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352012000600001 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352012000600001 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0102-09352012000600001 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais, Escola de Veterinária |
publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais, Escola de Veterinária |
dc.source.none.fl_str_mv |
Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.64 n.6 2012 reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online) instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
instname_str |
Universidade Federal de Minas Gerais (UFMG) |
instacron_str |
UFMG |
institution |
UFMG |
reponame_str |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
collection |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
repository.name.fl_str_mv |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG) |
repository.mail.fl_str_mv |
journal@vet.ufmg.br||abmvz.artigo@abmvz.org.br |
_version_ |
1750220885849014272 |