Detection of GBV-C/HGV RNA in cervico-vaginal smears from healthy individuals

• Autor(a) principal: Watanabe,Maria Angelica Ehara
• Data de Publicação: 2008
• Outros Autores: Miquelão,Ana Karina Melim Benthien, Oliveira,Carlos Eduardo Coral de, Oliveira,Karen Brajão de, Nasser,Thiago Franco, Aoki,Mateus Nóbrega, Suzuki,Patrícia Sayuri, Amarante,Marla Karine, Venâncio,Emerson José, Azevedo,Elbens Marcos Minoreli de
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Brazilian Archives of Biology and Technology
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000500007
• topic: GBV-C/HGV RNA; healthy women; cervicovaginal smears

The purpose of the present study was to evaluate the sexual transmission of GBV-C/HGV, through RNA detection in cervicovaginal smears. Therefore the GBV-C/HGV RNA in cervicovaginal smears from apparently healthy women was investigated using routine proceedings for prophylactic screening to cervical cancer. GBV-C/HGV RNA was detected by reverse transcriptase and polymerase chain reaction (RT-PCR). Only one woman presented co-infection with human papilloma virus (HPV). The GBV-C/HGV RNA was detected in 13/73 (17.57%) healthy women and it's prevalence in participating women between 28-43 years old was 53.85%. No association was found with GBV-C/HGV for the age of first sexual intercourse and number of pregnancies. In GBV-C/HGV RNA positive women, 69.23% were married. In conclusion, the present findings show that cervical and vaginal specimens could contain the GBV-C/HGV RNA.